5,553 research outputs found
Methodological Framework for Analysing Cascading Effects from Flood Events: The Case of Sukhumvit Area, Bangkok, Thailand
This is the final version of the article. Available from MDPI via the DOI in this record.Impacts from floods in urban areas can be diverse and wide ranging. These can include the loss of human life, infrastructure and property damages, as well as other kinds of nuisance and inconvenience to urban life. Hence, the ability to identify and quantify wider ranging effects from floods is of the utmost importance to urban flood managers and infrastructure operators. The present work provides a contribution in this direction and describes a methodological framework for analysing cascading effects from floods that has been applied for the Sukhumvit area in Bangkok (Thailand). It demonstrates that the effects from floods can be much broader in their reach and magnitude than the sole impacts incurred from direct and immediate losses. In Sukhumvit, these include loss of critical services, assets and goods, traffic congestion and delays in transportation, loss of business and income, disturbances and discomfort to the residents, and all these can be traced with the careful analysis of cascading effects. The present work explored the use of different visualization options to present the findings. These include a casual loop diagram, a HAZUR resilience map, a tree diagram and GIS maps.The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007–2013) under Grant Agreement No. 603663 for the research project PEARL (Preparing for Extreme and Rare events in coastaL regions). The authors are grateful to Opticits for providing the HAZUR software licence, within the collaboration of the EU H2020 research project RESCCUE (RESilience to cope with Climate Change in Urban arEas—a multisectorial approach focusing on water) Grant Agreement 700174
Age effect on retina and optic disc normal values
Purpose:
To investigate retinal thickness and optic disc parameters by the Retinal Thickness Analyzer (RTA) glaucoma program in older normal subjects and to determine any age effect.
Methods:
Subjects over 40 years of age without any prior history of eye diseases were recruited. Only subjects completely normal on clinical ophthalmologic examination and on visual field testing by Humphrey Field Analyzer (HFA) using the SITA 24-2 program were included. A total of 74 eyes from 74 subjects with even age distribution over the decades were enrolled and underwent topographic measurements of the posterior pole and of the optic disc by RTA. The `glaucoma full' program in software version 4.11B was applied.
Results:
Mean patient age was 59.9 +/- 10.3 years with a range from 40 to 80 years. The only parameter intraocular pressure (IOP) correlated with was retinal posterior pole asymmetry (r=0.27, p=0.02). IOP itself increased significantly with age (r=0.341, p=0.003). Mean defect and pattern standard deviation of the HFA did not correlate with any of the retinal or optic disc measurements. Increasing age correlated significantly with some of the morphologic measurements of the RTA: decreasing perifoveal minimum thickness (r=-0.258, p=0.026), increased cup-to-disc area ratio (r=0.302, p=0.016) and increased cup area (r=0.338 p=0.007).
Conclusions:
An age effect exists for some of the retina and optic disc measurements obtained by the RTA. Copyright (C) 2005 S. Karger AG, Basel
Functional redundancy between flavodiiron proteins and NDH-1 in Synechocystis sp. PCC 6803
In oxygenic photosynthetic organisms, excluding angiosperms, flavodiiron proteins (FDPs) catalyze light-dependent reduction of O(2)to H2O. This alleviates electron pressure on the photosynthetic apparatus and protects it from photodamage. InSynechocystissp. PCC 6803, four FDP isoforms function as hetero-oligomers of Flv1 and Flv3 and/or Flv2 and Flv4. An alternative electron transport pathway mediated by the NAD(P)H dehydrogenase-like complex (NDH-1) also contributes to redox hemostasis and the photoprotection of photosynthesis. Four NDH-1 types have been characterized in cyanobacteria: NDH-1(1)and NDH-1(2), which function in respiration; and NDH-1(3)and NDH-1(4), which function in CO(2)uptake. All four types are involved in cyclic electron transport. Along with single FDP mutants ( increment flv1and Delta flv3) and the double NDH-1 mutants ( increment d1d2, which is deficient in NDH-1(1,2)and increment d3d4, which is deficient in NDH-1(3,4)), we studied triple mutants lacking one of Flv1 or Flv3, and NDH-1(1,2)or NDH-1(3,4). We show that the presence of either Flv1/3 or NDH-1(1,2), but not NDH-1(3,4), is indispensable for survival during changes in growth conditions from high CO2/moderate light to low CO2/high light. Our results show functional redundancy between FDPs and NDH-1(1,2)under the studied conditions. We suggest that ferredoxin probably functions as a primary electron donor to both Flv1/3 and NDH-1(1,2), allowing their functions to be dynamically coordinated for efficient oxidation of photosystem I and for photoprotection under variable CO(2)and light availability
Shoulder pain due to cervical radiculopathy: an underestimated long-term complication of herpes zoster virus reactivation?
Purpose
To evaluate if herpes zoster virus (HZV) reactivation may be considered in the aetiology of cervical radiculopathy.
Methods
The study group was composed of 110 patients (52 M-58F;mean age ± SD:46.5 ± 6.12; range:40-73) with a clinical diagnosis of cervical radiculopathy. Patients with signs of chronic damage on neurophysiological studies were submitted to an X-ray and to an MRI of the cervical spine in order to clarify the cause of the cervical radiculopathy and were investigated for a possible reactivation of HZV; HZV reactivation was considered as “recent” or “antique” if it occurs within or after 24 months from the onset of symptoms, respectively. Data were submitted to statistics.
Results
Thirty-eight patients (34,5%,16 M-22F) had a history of HZV reactivation: four (2 M-2F) were “recent” and 34 (14 M-20F) were “antique”. In 68 of 110 participants (61,8%,30 M-38F), pathological signs on X-ray and/or MRI of the cervical spine appeared; in the remaining 42 (38,2%,22 M-20F) X-ray and MRI resulted as negative. Among patients with HZV reactivation, seven (18,4%) had a “positive” X-ray-MRI while in 31 (81,6%) the instrumental exams were considered as negative. The prevalence of “antique” HZV reactivations was statistically greater in the group of patients with no pathological signs on X-ray/MRI of the cervical spine with respect to the group with a pathological instrumental exam (p < 0.01).
Conclusions
It may be useful to investigate the presence of a positive history of HZV reactivation and to consider it as a long-term complication of a cervical root inflammation especially in patients in which X-ray and MRI of the cervical spine did not show pathological findings
Laser treatment in diabetic retinopathy
Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries due to macular edema and proliferative diabetic retinopathy (PDR). For both complications laser treatment may offer proven therapy: the Diabetic Retinopathy Study demonstrated that panretinal scatter photocoagulation reduces the risk of severe visual loss by >= 50% in eyes with high-risk characteristics. Pan-retinal scatter coagulation may also be beneficial in other PDR and severe nonproliferative diabetic retinopathy (NPDR) under certain conditions. For clinically significant macular edema the Early Treatment of Diabetic Retinopathy Study could show that immediate focal laser photocoagulation reduces the risk of moderate visual loss by at least 50%. When and how to perform laser treatment is described in detail, offering a proven treatment for many problems associated with diabetic retinopathy based on a high evidence level. Copyright (c) 2007 S. Karger AG, Basel
On-sky experiment of the discrete beam combiner: lessons learned and strategies for improved calibration of the transfer function
Changing insurance company claims handling processes improves some outcomes for people injured in road traffic crashes
<p>Abstract</p> <p>Background</p> <p>Regaining good health and returning to work are important for people injured in road traffic crashes and for society. The handling of claims by insurance companies may play an important role in the rate at which health recovers and return to work is actually attained.</p> <p>Methods</p> <p>A novel approach towards claims handling for people injured in road traffic accidents was compared to the standard approach. The setting was a large insurance company (NRMA Insurance) in the state of New South Wales, Australia. The new approach involved communicating effectively with injured people, early intervention, screening for adverse prognostic factors and focusing on early return to work and usual activities. Demographic and injury data, health outcomes, return to work and usual activities were collected at baseline and 7 months post-injury.</p> <p>Results</p> <p>Significant differences were found 7 months post-injury on 'caseness' of depression (<it>p </it>= 0.04), perceived health limitation on activities (<it>p </it>= 0.03), and self-reported return to usual activities (<it>p </it>= 0.01) with the intervention group scoring better. Baseline general health was a significant predictor for general health at 7 months (OR 11.6, 95% CI 2.7-49.4) and for return to usual activities (OR 4.6, 95% CI 2.3-9.3).</p> <p>Conclusion</p> <p>We found a few positive effects on health from a new claims handling method by a large insurance company. It may be most effective to target people who report low general health and low expectations for their health recovery when they file their claim.</p
Extension of non-minimal derivative coupling theory and Hawking radiation in black-hole spacetime
We study the greybody factor and Hawking radiation with a non-minimal
derivative coupling between the scalar field and the curvature in the
background of the slowly rotating Kerr-Newman black hole.
Our results show that both the absorption probability and luminosity of
Hawking radiation of the scalar field increase with the coupling.
Moreover, we also find that for the weak coupling , the
absorption probability and luminosity of Hawking radiation decrease when the
black hole's Hawking temperature decreases; while for stronger coupling
, the absorption probability and luminosity of Hawking radiation
increase on the contrary when the black hole's Hawking temperature decreases.
This feature is similar to the Hawking radiation in a -dimensional static
spherically-symmetric black hole surrounded by quintessence \cite{chensong}.Comment: 17 pages, 6 figures, 1 table, Title changed, Appendix changed,
accepted by JHE
B-> D* zero-recoil formfactor and the heavy quark expansion in QCD: a systematic study
We present a QCD analysis of heavy quark mesons focussing on the B -> D*
formfactor at zero recoil, F_D*(1). An advanced treatment of the perturbative
corrections in the Wilsonian approach is presented. We estimate the
higher-order power corrections to the OPE sum rule and describe a refined
analysis of the nonresonant continuum contribution. In the framework of a
model-independent approach, we show that the inelastic contribution in the
phenomenological part of the OPE is related to the mQ-dependence of the
hyperfine splitting and conclude that the former is large, lowering the
prediction for F_D*(1) down to about 0.86. This likewise implies an enhanced
yield of radial and D-wave charm excitations in semileptonic B decays and
alleviates the problem with the inclusive yield of the wide excited states. We
also apply the approach to the expectation values of dimension 7 and 8 local
operators and to a few other issues in the heavy quark expansion.Comment: 70 pages, 13 figure
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