Encephalopathy and encephalitis during acute SARS-CoV-2 infection. Spanish Society of Neurology COVID-19 Registry

Objectives: Since the beginning of the COVID-19 pandemic, the Spanish Society of Neurology has run a registry of patients with neurological involvement for the purpose of informing clinical neurologists. Encephatopathy and encephalitis were among the most frequently reported complications. In this study, we analyse the characteristics of these complications. Patients and methods: We conducted a retrospective, descriptive, observational, multicentre study of patients with symptoms compatible with encephalitis or encephalopathy, entered in the Spanish Society of Neurology''s COVID-19 Registry from 17 March to 6 June 2020. Results: A total of 232 patients with neurological symptoms were registered, including 51 cases of encephalopathy or encephalitis (21.9%). None of these patients were healthcare professionals. The most frequent syndromes were mild or moderate confusion (33%) and severe encephalopathy or coma (9.8%). The mean time between onset of infection and onset of neurological symptoms was 8.02 days. Lumbar puncture was performed in 60.8% of patients, with positive PCR results for SARS-CoV-2 in only one case. Brain MRI studies were performed in 47% of patients, with alterations detected in 7.8% of these. EEG studies were performed in 41.3% of cases, detecting alterations in 61.9%. Conclusions: Encephalopathy and encephalitis are among the complications most frequently reported in the registry. More than one-third of patients presented mild or moderate confusional syndrome. The mean time from onset of infection to onset of neurological symptoms was 8 days (up to 24 hours earlier in women than in men). EEG was the most sensitive test in these patients, with very few cases presenting alterations in neuroimaging studies. All patients treated with boluses of corticosteroids or immunoglobulins progressed favourably. (C) 2021 Sociedad Espanola de Neurologia. Published by Elsevier Espana, S.L.U

Variabilidade espacial de propriedades de Latossolo e da produção de café em diferentes superfícies geomórficas Spatial variability of Latosol properties in different geomorphic surfaces of coffee cultivation

Com o objetivo de avaliar a variabilidade espacial de propriedades do solo e produção de café em diferentes Superfícies Geomórficas (SG) na região do Alto Paranaíba, MG, instalaram-se duas malhas de 200 x 850 m com intervalos regulares de 50 m, com 68 pontos amostrais cada uma, sob cultivo de café. As amostras de solo foram coletadas na profundidade de 0-0,20 m, nos pontos de intercessão dessas malhas. A produção de café foi avaliada em duas colheitas de grãos em coco das plantas mais próximas da intercessão de linhas das malhas. Calcularam-se as estatísticas descritivas e realizou-se a análise geoestatística de propriedades do solo e produção da cultura de café. As propriedades químicas e granulométricas de solos intensamente manejados, possuem dependência do relevo, mesmo de pequena expressão. A produção de café apresentou dependência espacial em ambas as superfícies e maior variabilidade na SG II. Os limites entre as superfícies geomórficas podem representar limites de locais específicos de manejo.<br>With the objective to evaluate the spatial variability of the soil properties and coffee production in different geomorphic surfaces (GS) in the region of the high Paranaíba, MG, two regular grids of 200 x 850 m with intervals of 50 m were installed with 68 sampling points under coffee crop. The soil samples were collected at 0-0.20 m depth at the intersection points of these grids. The coffee production was evaluated in plants closer to the intersection of the grid point. Descriptive statistics and geostatistics analysis of the soil properties and production of coffee crop were performed. The chemical and textural properties of soil intensely managed possess dependence of the relief, even for small expression. The coffee production presented spatial dependence in both surfaces and largest variability in GS II. The limits between the geomorphic surfaces can represent limits of specific places of management