Enantiocontrol in the intermolecular cyclopropanation reaction catalyzed by dirhodium(II) complexes with ortho-metalated aryl phosphine ligands

(P) and (M) dirhodium(II) complexes with ortho-metalated aryl phosphines are assessed as chiral catalysts in the enantioselective cyclopropanation of styrenes by ethyl diazoacetate; enantioselectivities up to 91% and up to 87%, respectively, for cis- and trans-2-arylcyclopropanecarboxylates are observed.Barberis, Mario, [email protected] ; Lahuerta Peña, Pascual, [email protected] ; Perez Prieto, Julia, [email protected] ; Sanau Torrecilla, Mercedes, [email protected]

Enantio- and diastereocontrol in intermolecular cyclopropanation reaction of styrene catalyzed by dirhodium(II) complexes with bulky ortho-metalated aryl phosphines

Enantiomerically pure dirhodium(II) complexes with ortho-metalated p-substituted aryl phosphines have been shown to be enantio- and diastereoselective in the cyclopropanation of styrene by ethyl diazoacetate. Enantioselectivities up to 91% and diastereoselectivities up to 90% are observed for ethyl cis-2-phenylcyclopropanecarboxylate.Estevan Estevan, Francisco, [email protected] ; Lahuerta Peña, Pascual, [email protected] ; Lloret Fillol, Julio, [email protected] ; Sanau Torrecilla, Mercedes, [email protected] ; Ubeda Picot, M Angeles, [email protected] ; Vila Gomez, Jaume Llorenc, [email protected]