10,357 research outputs found

    Beyond Ethnicity: Toward a Critique of the Hegemonic Discipline E. San Juan, Jr.

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    With the current vogue of multiculturalism and cultural diversity requirements as panacea for systemic problems, scholars and teachers of Ethnic Studies need to reassess the principles and goals of their discipline. Los Angeles 1992, among other developments, has exposed the serious inadequacies of old paradigms. A review of the racialized history of Asians in U.S. society, a narrative of oppression and opposition now mystified by the model minority myth, allows us to grasp the flaws of the liberal pluralist focus on culture divorced from the political and economic contexts of unequal power relations. Ultimately, for whom is Ethnic Studies designed? By historicizing identity politics and validating the genealogy of resistance, we in the field of Ethnic Studies can refuse to be mere apologists for the status quo and revitalize the critical and emancipatory thrust of Ethnic Studies, a thrust inseparable from the struggle of people of color against white supremacy

    From Chinatown to Gunga Din Highway: Notes on Frank Chin\u27s Writing Strategy

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    Exploring Frank Chin\u27s work, particularly in his latest novel Gunga Din Highway, the essay endeavors to re-situate ethnic writing in the historical specificity of its inscription in the United States as a racial polity. This cognitive remapping of the literary field as reconfigured by multiculturalist liberalism may be accomplished by examining Chin\u27s cultural politics. Chin\u27s mode of strategic writing interrogates the modelminority myth and the premises of cultural nationalism. While it rejects the pluralist resolution of the traditional conflicts in the Chinese diaspora, Chin\u27s satiric impulse proposes a defamiliarization of Asian American common sense adequate to provoke a revaluation of the presumed conjunction of ethnicities, cultures, and nationalities in the current counter-terrorist milieu

    Application of nitroarene dioxygenases in the design of novel strains that degrade chloronitrobenzenes.

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    Widespread application of chloronitrobenzenes as feedstocks for the production of industrial chemicals and pharmaceuticals has resulted in extensive environmental contamination with these toxic compounds, where they pose significant risks to the health of humans and wildlife. While biotreatment in general is an attractive solution for remediation, its effectiveness is limited with chloronitrobenzenes due to the small number of strains that can effectively mineralize these compounds and their ability to degrade only select isomers. To address this need, we created engineered strains with a novel degradation pathway that reduces the total number of steps required to convert chloronitrobenzenes into compounds of central metabolism. We examined the ability of 2-nitrotoluene 2,3-dioxygenase from Acidovorax sp. strain JS42, nitrobenzene 1,2-dioxygenase (NBDO) from Comamonas sp. strain JS765, as well as active-site mutants of NBDO to generate chlorocatechols from chloronitrobenzenes, and identified the most efficient enzymes. Introduction of the wild-type NBDO and the F293Q variant into Ralstonia sp. strain JS705, a strain carrying the modified ortho pathway for chlorocatechol metabolism, resulted in bacterial strains that were able to sustainably grow on all three chloronitrobenzene isomers without addition of co-substrates or co-inducers. These first-generation engineered strains demonstrate the utility of nitroarene dioxygenases in expanding the metabolic capabilities of bacteria and provide new options for improved biotreatment of chloronitrobenzene-contaminated sites
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