Factors Influencing High Yielding Wheat Varieties Adoption by Smallholder Farmers in Ethiopia

Wheat yield is low in Ethiopia. Adoption of high yielding wheat varieties is one of the measures presumed to enhance wheat yield in the country. However, there are several socio-economic and institutional factors that limit the adoption of high yielding wheat varieties. The main objective of this study was to analyze factors affecting adoption of high yielding wheat varieties by small holder farmers in Ethiopia. The study used cross-sectional data collected from sample of 174 farm households selected through two-stage stratified random sampling techniques. Descriptive statistics and econometric models were used to analyze the data. Probit model was employed for adoption analyze of high yielding wheat varieties. The probit model result depicted that land holding size, tropical livestock unit, access to agricultural information, frequency of extension contacts, off-farm income and perception of farmers toward attributes of high yielding wheat varieties affected the likelihood of adoption of high yielding wheat varieties positively and significantly. But, sex of household heads and affiliation to organizations had negative and significant effect on the adoption of high yielding wheat varieties. The finding suggest that the government and stakeholders should need to focus on improving farm land and livestock productivity, strengthening frequency of extension visits, encouraging participation in non-farm activities, creating reliable information and awareness towards farmers’ perceptions in the area. Finally, further support of high yielding wheat varieties adoption should be given due attention for smallholders. Keywords: Adoption, High yielding wheat varieties, Smallholder, Binary probi

In vitro antibacterial activity of leaf extracts of Zehneria scabra and Ricinus communis against Escherichia coli and methicillin resistance Staphylococcus aureus

ABSTRACTObjectiveTo evaluate the antibacterial activities of the crude leaves extracts of Zehneria scabra (Z. scabra) and Ricinus communis (R. communis) against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus) and methicillin resistance S. aureus.MethodsThe crude powdered leaves of Z. scabra and R. communis were extracted successively by organic solvents in increasing polarity [benzene, chloroform:acetone (1:1), 70% alcohol and distilled water]. The antibacterial susceptibility of the crude leaves extracts of were tested against standard strains of E. coli (ATCC 25922) and S. aureus (ATCC 2923) and clinical isolates of E. coli, S. aureus and methicillin resistance S. aureus using agar well diffusion method.ResultsIn Z. scabra and R. communis leaf extracts, the most sensitive standard strain was S. aureus with an inhibition zone of (14.00±1.20) mm and (15.90±2.13) mm, respectively. The minimum inhibitory concentration (MIC) values of Z. scabra extracts against test organisms ranged from 1.95 mg/mL for extract 3 in clinical and standard strains of S. aureus to 250 mg/mL for extract 1 and 4 in clinical and standard strains of E. coli. The MIC values of R. communis extracts against test organisms ranged from 1.95 mg/mL for extract 2 and 3 standard strains of S. aureus to 250 mg/mL for extract 1 in clinical isolate of E. coli. Most of the minimum bactericidal concentration and MIC values of plant extracts were almost similar particularly in R. communis, or minimum bactericidal concentration equal to one dilution factor less than MIC value of the extracts mainly in Z. scabra.ConclusionsThe potency of plant extracts against test organisms were depend on different organic solvents used. Clinical isolate of bacterial pathogens showed less zones of diameter compared to the standard strains. Gram-positive had wide inhibition zones than Gram-negative bacteria. Further studies should be carried out to isolate the pure compounds and standardization of the methods of plant extracts for an in vitro testing

Postpartum anemia and its determinant factors among postnatal women in two selected health institutes in Gondar, Northwest Ethiopia: A facility-based, cross-sectional study

BackgroundAnemia is highly prevalent globally and disproportionately affects postnatal women. It is a significant cause of maternal mortality and morbidity globally.ObjectiveThe main aim of this study was to determine the extent of postpartum anemia and associated factors among postnatal women in two selected health facilities in Gondar, Northwest Ethiopia.MethodsA facility-based, cross-sectional study was conducted among 282 postnatal women from March to May 2021. A systematic sampling technique was used to recruit study participants from each institute. Sociodemographic, obstetric, and clinical data were collected through a semi-structured questionnaire. A venous blood sample was collected to determine the red blood cell parameters. A thin blood smear preparation was performed to examine blood morphology. In addition, direct wet mount and formalin-ether sedimentation techniques were used for stool examination to identify intestinal parasites. Data were entered into EpiData and exported to Stata 14 for statistical analysis. Descriptive statistics were presented in text, tables, and figures. A binary logistic regression model was used to identify factors associated with postpartum anemia. A p-value <0.05 was considered statistically significant.ResultsThe proportion of postpartum anemia was 47.16%; 95% CI; 41.30–53.03 with moderate, mild, and severe anemia accounting for 45.11, 42.86, and 12.03%, respectively. The majority of the anemia (94%) was of the normocytic normochromic type. It was associated with postpartum hemorrhage (AOR = 2.23; 95% CI: 1.24–4.01), cesarean section (AOR = 4.10; 95% CI: 2.11–7.78), lack of iron and folate supplementation during pregnancy (AOR = 2.12; 95% CI: 1.17–4.02), and low diet diversity level (AOR = 1.83; 95% CI: 1.05–3.18).ConclusionThe prevalence of anemia was found to be a major public health concern. Iron and folate supplementation during pregnancy, improved management of PPH, an effective cesarean section with post-operative care, and taking a diversified diet will reduce the burden. Therefore, identified factors should be considered to prevent and control postpartum anemia

Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action

Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or “golden rules,” for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice

Water purification and antibacterial efficacy of Moringa oleifera Lam

Abstract Background Plants are rich in secondary metabolites and are being used for the treatment of various ailments in the indigenous system of medicine. Many developing countries are facing illnesses, and deaths among children are caused by germs, which get into the mouth via water and food. In addition, it has been estimated that up to 80% of all disease and sickness in the world is caused by inadequate sanitation, polluted water or unavailability of water. Thus, this study investigates the water purifying property of Moringa oleifera seed powder and determines the role of seed extracts against a few bacterial growths. Methods Water samples were obtained randomly during January and February, 2015, from the Angereb and Shinta rivers, Gondar, Ethiopia. Both sites of water samples were subjected for purification studies and treated with dried seed powder. Treated water samples were subjected to bacteriological analysis using most probable number technique. Results Addition of aluminum sulfate as a coagulant lowered the water pH from 7.2 to 3.66, while the seed extract water pH remained the same. Treatment of 0.016 g/L of M. oleifera decreased water turbidity from 208.3 nephelometric turbidity units (NTU) to 33.66 NTU (83.84%) and from 129 NTU to 16.8 NTU (86.98%) for the Shinta and Angereb river water samples, respectively. The highest microbial load reduction was found with the Angereb (97.17%) and Shinta (97.50%) rivers. The acetone extracts showed maximum antibacterial activity with 19.00 mm against Salmonella typhii (clinical isolate), while Shigella dysenteriae (clinical isolate) was the least sensitive with 7.66 mm on the aqueous extract. The most frequent MIC value was 6.25 mg/mL followed by 12.5 mg/mL. The acetone extract is the most potent in inhibiting and killing the test organisms at a very low concentration for Shigella typhii. Conclusion Taken together, the seed powder exhibits a remarkable reduction in turbidity and coliform count which makes the seed powder a good source for water purification. The acetone extract of seed had a strong antibacterial activity. It reveals that the seed powder and its extract can control and reduce waterborne bacterial diseases. This investigation facilitates benefits to those who cannot afford and or have access to clean drinking water in Ethiopia and elsewhere

Evaluation of Chickpea Varieties and Fungicides for the Management of Chickpea Fusarium Wilt Disease (Fusarium oxysporum f.sp. ciceris) at Adet Sick Plot in Northwest Ethiopia

A 2-year experiment was conducted at wilt sick plot infested with natural occurring Fusarium oxysporum f.sp. ciceris at Adet Agricultural Research Center in northwestern Ethiopia with an aim to evaluate effective chickpea varieties and fungicides for the management of chickpea fusarium wilt in order to integrate chickpea varieties and fungicides. Four varieties, namely, Shasho, Arerti, Marye, and local, two fungicides, namely, Apron Star and mancozeb, and untreated local chickpea were used as treatments. Treatments were arranged in a factorial combination in randomized complete block design in three replications. There were significant differences at p<0.05 in the overall mean of fusarium wilt disease incidence, area under disease progress curve %-day, yield and yield components among varieties and fungicides treatments. Data were analyzed using SAS system version 9.2. The results indicated that the maximum disease incidence and area under disease progress curve values 65.62% and 578.5%-day, respectively, were recorded from untreated local chickpea, while the minimum disease incidence and area under disease progress curve values 23.41% and 147%-day, respectively, were recorded from Shasho variety treated with Apron Star. The maximum biomass and grain yield of 6.71 t/ha and 4.6 t/ha, respectively, were recorded from Shasho variety treated with Apron Star while the minimum biomass and grain yield of 0.62 t/ha and 0.21 t/ha, respectively, were recorded from untreated local chickpea. Thus, the experiment results suggested that the variety of Shasho treated with fungicide Apron Star caused significant reduction in chickpea fusarium wilt incidence leading to a corresponding increase in grain yield of chickpea

Prevalence of biofilm producing Acinetobacter baumannii clinical isolates: A systematic review and meta-analysis.

BackgroundAcinetobacter baumannii, the first human pathogen to be designated as a "red-alert" pathogen, is on the critical priority list of pathogens requiring new antibiotics. Biofilm-associated diseases are the most common infections caused by the antibiotic-resistant bacteria A. baumannii. Multidrug-resistant strains are more easily transmitted around the world due to A. baumannii's ability to produce biofilms, which allows it to develop antibiotic resistance mechanisms and thrive in healthcare environments. As a result, A. baumannii infections are becoming increasingly common in hospital settings allover the world. As a result, a comprehensive systematic review and meta-analysis were carried out to determine the global prevalence of biofilm-producing A. baumannii clinical isolates.MethodsArticles were extensively searched in bibliographic databases and grey literatures using entry terms or phrases. Studies meeting eligibility criteria were extracted in MS Excel and exported into STATA version 12 software for statistical analysis. A random-effects model was used to compute the pooled prevalence of biofilm-producing A. baumannii clinical isolates. The heterogeneity was quantified by using the I2 value. Publication bias was assessed using a funnel plot and Egger's test. Sensitivity analysis was done to assess the impact of a single study on pooled effect size.ResultOf the 862 studies identified, 26 studies consisted of 2123 A.baumannii clinical isolates of which 1456 were biofilm-producing. The pooled prevalence of biofilm-producing A.baumannii clinical isolates was 65.63% (95% CI = 56.70%-74.56%). There was substantial heterogeneity with an I2 value of 98.1%. Moreover, 41.34%, 33.57%, and 27.63% of isolates of strong, mild, and weak producers of biofilm. Higher prevalence was found in studies published after 2014 (66.31%); Western Pacific region (76.17%); and Asia (66.22%) followed by the African continent (57.29%).ConclusionThe pooled prevalence of biofilm-producing A. baumannii clinical isolates has risen alarmingly, posing a public health risk. This indicates the burden of biofilm-producing A. baumannii infections urges routine screening and appropriate treatment for better management of hospitalized patients, as well as effective controlling of the emergence of drug resistance. Furthermore, this finding is an alert call for the stakeholders to develop strong infection prevention and antibiotics stewardship programs for the prevention and control of biofilm-producing bacterial infections