Polybrominated Diphenyl Ethers and Other Persistent Organic Pollutants in Serum Pools from the National Health and Nutrition Examination Survey: 2001–2002

Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and persistent pesticides have been measured in serum pools from participants 3–5, 6–11, 12–19, 20–39, 40–59, and ≥60 years of age from the 2001–2002 National Health and Nutrition Examination Survey. For 2,2′,4,4′-tetrabromodiphenyl ether (PBDE-47), the unweighted (not adjusted for sampling weights) arithmetic mean concentration (±95% confidence interval) was 3.4 times higher in 3–5-year-olds (216 ± 30 ng/g of lipid) than in 12–19-year-olds (64 ± 11 ng/g of lipid), with no apparent change with increasing age for adults ≥20 years of age. By contrast, unweighted arithmetic mean concentrations of traditional persistent organic pollutants (POPs) such as hexachlorobenzene (HCB) and 2,2′,3,3′,4,4′,5,5′-octachlorobiphenyl (PCB194) were 2- and 20-fold higher, respectively, in persons ≥60 years than in 12–19-year-old adolescents. Findings suggest higher exposures to PBDEs but lower exposures to traditional POPs in 3–5-year-old children than in adults

Polybrominated Diphenyl Ethers, Polychlorinated Biphenyls, and Persistent Pesticides in Serum from the National Health and Nutrition Examination Survey: 2003–2008

Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and persistent pesticides have been measured in pooled samples representative of the general noninstitutionalized population of the United States. The pools were made from individual sera from the National Health and Nutrition Examination Survey (NHANES) during 2005/06 and 2007/08. The pooled concentrations have been contrasted to NHANES 2003/04 individual measurements to evaluate changes in concentration over time and within survey period differences among age groups, race/ethnicity groups (Mexican American, non-Hispanic Black, non-Hispanic White), and sex. The arithmetic mean serum concentrations of several PCB congeners decreased from NHANES 2003/04 through 2007/08. Larger percentage reductions were seen for younger subjects (12–19 years) compared with older subjects (≥60 years). For example, the arithmetic mean concentration of 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB-153) was 36% lower in 12–19 year old adolescents when comparing NHANES 2007/08 with 2003/04; while for subjects over the age of 60 a 14% lower concentration was seen, although, the 95% confidence intervals overlapped. Similarly, the arithmetic mean serum concentrations of tri- to hexaBDEs were lower in NHANES 2007/08 than in 2003/04; however, most confidence intervals of the arithmetic means overlapped. These findings suggest that a reduction in PBDE serum concentrations cannot yet be detected following the discontinuation of pentaBDE in 2004

Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring Measurements-0

<p><b>Copyright information:</b></p><p>Taken from "Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring Measurements"</p><p>Environmental Health Perspectives 2004;113(2):192-200.</p><p>Published online 23 Sep 2004</p><p>PMCID:PMC1277864.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p