Nutrigenomics and immune function in fish : new insights from omics technologies

This study was funded by BBSRC grant BB/M026604/1.Peer reviewedPublisher PD

Constraints to the Growth of Native American Gaming

Since the Indian Gaming Regulatory Act was passed in 1988, high-stakes bingo halls and casino operations have spread to reservations across the country and generated millions of dollars in revenues for their respective tribes. While some tribes have been able to exploit their sovereign status and establish high-stakes bingo parlors and casinos on reservations across the country, this study describes how external and internal constraints limit the adoption of gaming ventures by other tribes. Constraints include the location of the reservations, increasing competition, disagreements among tribal members, and opposition from the private and public sectors

Nematic order by elastic interactions and cellular rigidity sensing

We predict spontaneous nematic order in an ensemble of active force generators with elastic interactions as a minimal model for early nematic alignment of short stress fibers in non-motile, adhered cells. Mean-field theory is formally equivalent to Maier-Saupe theory for a nematic liquid. However, the elastic interactions are long-ranged (and thus depend on cell shape and matrix elasticity) and originate in cell activity. Depending on the density of force generators, we find two regimes of cellular rigidity sensing for which orientational, nematic order of stress fibers depends on matrix rigidity either in a step-like manner or with a maximum at an optimal rigidity.Comment: 12 pages, 4 figure

Microscale application of column theory for high resolution force and displacement sensing

We present the design, fabrication and experimental validation of a novel device that exploits the amplification of displacement and attenuation of structural stiffness in the post-buckling deformation of slender columns to obtain pico-Newton force and nanometer displacement resolution even under an optical microscope. The extremely small size, purely mechanical sensing scheme and vacuum compatibility of the instrument makes it compatible with existing visualization tools of nanotechnology. The instrument has a wide variety of potential applications ranging from electro-mechanical characterization of one dimensional solids to single biological cells

Pade Approximants, Optimal Renormalization Scales, and Momentum Flow in Feynman Diagrams

We show that the Pade Approximant (PA) approach for resummation of perturbative series in QCD provides a systematic method for approximating the flow of momentum in Feynman diagrams. In the large-$\beta_0$ limit, diagonal PA's generalize the Brodsky-Lepage-Mackenzie (BLM) scale-setting method to higher orders in a renormalization scale- and scheme-invariant manner, using multiple scales that represent Neubert's concept of the distribution of momentum flow through a virtual gluon. If the distribution is non-negative, the PA's have only real roots, and approximate the distribution function by a sum of delta-functions, whose locations and weights are identical to the optimal choice provided by the Gaussian quadrature method for numerical integration. We show how the first few coefficients in a perturbative series can set rigorous bounds on the all-order momentum distribution function, if it is positive. We illustrate the method with the vacuum polarization function and the Bjorken sum rule computed in the large-$\beta_0$ limit.Comment: 28 pages, LaTeX, including 6 figures requires epsfig.st

Suicide by Bomb, with Decapitation

Suicide by explosion is rare outside of the context of terrorist activities. We present a case of a man with a history of explosives expertise who committed suicide by bomb/decapitation. The case serves to remind forensic pathologists of several important issues when presented with a case involving explosives, such as ensuring the safety of all those involved in the investigation and the importance of interagency cooperation. Potentially invaluable ancillary tests at autopsy include performing radiology, collecting trace evidence, retaining clothing, ensuring the positive identity of the decedent, and recognizing the importance of documenting injury types and patterns