Application of activated carbon impregnated composite ceramic filters in cassava mill effluent treatment: prospects and limitations

Disposal of poorly managed cassava mill effluent often results in serious environmental degradation. A low-cost treatment option was developed to alleviate this rising concern prevalent among third world processors. Frustum-shaped ceramic filters produced by mixing different proportions of sawdust and activated carbon with equal amounts of clay, kaolin and sherds powder and sintered at 850°C was assessed in this study. The results indicated pollutant removal efficiency ranging from 6.5 to 98.1% with the best removal efficiency obtained for chemical oxygen demand (COD) [97.9 - 98.1%] closely followed by biochemical oxygen demand (BOD) [71.24 - 77.14%] while (24.13 - 30.72%) and (6.5 - 71.7%) were obtained for turbidity and hydrogen cyanide respectively. The filter with 12.8% of sawdust, 5.1% of activated carbon, 7.13% of kaolin, 3.6% of sherds powder and 71.3% of clay gave the best removal efficiency. A maximum flow rate of 0.0035 L/H (LPH) was recorded with a corresponding time of first drop of 216 minutes. The high removal efficiency observed for some parameters, locally available construction materials and wastewater reuse options makes this a viable option for cassava mill effluent treatment, however, further study is required to optimize this technique to meet wastewater permissible limits

Design and Preliminary Evaluation of a Dry Cowpea Dehuller

Cowpea dehulling is an important operation in the processing of cowpea. Traditional cowpea dehulling methods recognize the soaking of cowpea in water for a significant amount of time before manual abrasion is carried out either through the use of mortar and pestle, hands, or legs. Existing mechanical alternatives also require prolonged soaking of cowpea before dehulling occurs in addition to being expensive and beyond the reach of many rural populations. This study designed and fabricated a dry cowpea dehulling machine using engineering principles and with locally available materials. Components of the machine include the hopper, power transmission drive, dehulling chamber, polishing chamber, sieves, discharge chute, and agitator. Dry cowpea varieties of Brown Drum (15%Mc dB) and Oloyin (17.5%Mc dB) cowpea weighing 500 g each were fed into the machine at a constant speed of 358 rpm. Preliminary tests showed the “Brown Drum” cowpea variety recorded a maximum dehulling efficiency of 97.44% in 7 minutes while the Oloyin variety was completely dehulled in 7 minutes at 98.75% efficiency. The throughput capacity recorded was 450kg/hr and this machine raises the possibility of producing dry dehulled cowpea for domestic and industrial end-users

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Comparative study on the use of Moringa oleifera as natural coagulant and aluminium sulphate in restaurant wastewater treatment

The enormous amount of wastewater generated by restaurants often require some level of treatment before disposal. This is partly achieved by using synthetic coagulants with its attendant environmental risk. This study is aimed at investigating the use of Aluminium Sulphate (AS) and Moringa oleifera (MO) for treating restaurant wastewater (RW). Different doses (0, 50, 100, and 150 mg/l) of the prepared stock solution of AS and MO were applied to 1000 ml of RW collected from a University restaurant. The result showed that the treated sample pH reduced from 7.55 to 6.86 and 7.0 at an optimum dose of 150 and 50 ml for AS and MO while conductivity increased from 1.03 to 2.22 mg/l and 1.74 mg/l for AS and MO, respectively. Turbidity reduced from 44.73 mg/l to 5.20 mg/l for MO and 5.77 mg/l for AS; dissolved oxygen increased from 0.35 to 0.51 mg/l and 0.70 mg/l for MO and AS; Magnesium reduced from 21.11 to 14.77 mg/l for MO, but increased to 29.07 mg/l for AS; Zinc increased from 1.19 to 6.15 mg/l for MO and 7.10 mg/l for AS, while Calcium increased from 2.02 mg/l to 5.09 mg/l for MO, and 3.09 mg/l for AS. The MO seed extract achieved a better reduction of pH and turbidity at higher dose while no distinct trend was observed in all the parameters when AS was applied. Doses of MO seed extract can be further optimized and applied as a low cost option for RW treatment

Adaptation of the Wound Healing Questionnaire universal-reporter outcome measure for use in global surgery trials (TALON-1 study): mixed-methods study and Rasch analysis

BackgroundThe Bluebelle Wound Healing Questionnaire (WHQ) is a universal-reporter outcome measure developed in the UK for remote detection of surgical-site infection after abdominal surgery. This study aimed to explore cross-cultural equivalence, acceptability, and content validity of the WHQ for use across low- and middle-income countries, and to make recommendations for its adaptation.MethodsThis was a mixed-methods study within a trial (SWAT) embedded in an international randomized trial, conducted according to best practice guidelines, and co-produced with community and patient partners (TALON-1). Structured interviews and focus groups were used to gather data regarding cross-cultural, cross-contextual equivalence of the individual items and scale, and conduct a translatability assessment. Translation was completed into five languages in accordance with Mapi recommendations. Next, data from a prospective cohort (SWAT) were interpreted using Rasch analysis to explore scaling and measurement properties of the WHQ. Finally, qualitative and quantitative data were triangulated using a modified, exploratory, instrumental design model.ResultsIn the qualitative phase, 10 structured interviews and six focus groups took place with a total of 47 investigators across six countries. Themes related to comprehension, response mapping, retrieval, and judgement were identified with rich cross-cultural insights. In the quantitative phase, an exploratory Rasch model was fitted to data from 537 patients (369 excluding extremes). Owing to the number of extreme (floor) values, the overall level of power was low. The single WHQ scale satisfied tests of unidimensionality, indicating validity of the ordinal total WHQ score. There was significant overall model misfit of five items (5, 9, 14, 15, 16) and local dependency in 11 item pairs. The person separation index was estimated as 0.48 suggesting weak discrimination between classes, whereas Cronbach's α was high at 0.86. Triangulation of qualitative data with the Rasch analysis supported recommendations for cross-cultural adaptation of the WHQ items 1 (redness), 3 (clear fluid), 7 (deep wound opening), 10 (pain), 11 (fever), 15 (antibiotics), 16 (debridement), 18 (drainage), and 19 (reoperation). Changes to three item response categories (1, not at all; 2, a little; 3, a lot) were adopted for symptom items 1 to 10, and two categories (0, no; 1, yes) for item 11 (fever).ConclusionThis study made recommendations for cross-cultural adaptation of the WHQ for use in global surgical research and practice, using co-produced mixed-methods data from three continents. Translations are now available for implementation into remote wound assessment pathways