7 research outputs found
A retrospective evaluation of crown-fractured permanent teeth treated in a pediatric dentistry clinic
No full textOxygen Saturation in the Dental Pulp of Maxillary Premolars in Different Age Groups - Part 1
No full textEvaluation of Nd:YAG laser on partial oxygen saturation of pulpal blood in anterior hypersensitive teeth
No full textSearching in Mother Nature for Anti-Cancer Activity: Anti-Proliferative and Pro-Apoptotic Effect Elicited by Green Barley on Leukemia/Lymphoma Cells
No full textThe enigma of caspase-2: the laymen's view
No full textInternational audienceProteolysis of cellular substrates by caspases (cysteine-dependent aspartate-specific proteases) is one of the hallmarks of apoptotic cell death. Although the activation of apoptotic caspases is considered a 'late-stage' event in apoptosis signaling, past the commitment stage, one caspase family member, caspase-2, splits the cell death community into half-those searching for evidence of an apical initiator function of this molecule and those considering it as an amplifier of the apoptotic caspase cascade, at best, if relevant for apoptosis at all. This review screens past and present biochemical as well as genetic evidence for caspase-2 function in cell death signaling and beyond
