Macrolide-Clarithromycin Task-Force for the Treatment and Prophylaxis of Covid-19 as a Single Agent

SARS-CoV-2 is a novel RNA coronavirus responsible of a deadly pandemic: the clinical illness COVID-19. With only one authorized drug for emergency use in critically ill patients: Remdesivir, there is not any other approved drug or vaccine yet with proven potential to overcome this infection. We exposed here many scientific evidences to support our novel idea that a macrolide, basically Clarithromycin, could be effective as a single agent for treatment and prophylaxis of COVID-19. Clarithromycin could change the history of this pandemic. It could reduce the costs of treatment and the potential adverse effects when combining more than one drug such as with Hydroxychloroquine. Clarithromycin treatment and prophylaxis as a single agent could be much more simple, safe and cheaper as giving Chloroquine or Hydroxychloroquine alone or in combination with Azithromycin as well as other therapeutic options.Fil: Mansilla, Eduardo. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Martínez, Ricardo Rangel. ExomePharma; MéxicoFil: Marin, Gustavo Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Filho, Idiberto Zotarelli. Faceres Medical School; BrasilFil: Rivas, Elsa. Hospital de la Amistad Perú - Corea San Rosa II; PerúFil: Rivas, Jaime. Hospital de la Amistad Perú - Corea San Rosa II; PerúFil: Carvalho, Katherine Athayde Teixeira de. Research Institute Pelé Little Prince; BrasilFil: Dayer, Mohammad Reza. Shahid Chamran University of Ahvaz; IránFil: Samadikuchaksaraei, Alí. Iran University of Medical Sciences; Irá