Confirmation of the microarray data for the <i>ABCB7</i> gene using real-time quantitative PCR.

<p>Confirmation of the microarray data for the <i>ABCB7</i> gene using real-time quantitative PCR.</p

Frequency of mutations in normal karyotype AML samples.

*<p>One primary AML sample presented concomitant <i>FLT3-ITD</i> and <i>FLT3-TKD</i> mutations.</p

Descriptive statistics of <i>ABCB7</i> expression levels in CD34⁺ cells according to FAB group, in CD34⁺ cells according to percentage of bone marrow ring sideroblasts, and in cultured erythroblasts at day 7.

<p>Descriptive statistics of <i>ABCB7</i> expression levels in CD34⁺ cells according to FAB group, in CD34⁺ cells according to percentage of bone marrow ring sideroblasts, and in cultured erythroblasts at day 7.</p

Concurrence of mutations in 16 genes analyzed in CN-AML samples.

<p>Columns show results for each of the 84 analysed cases. Solid boxes indicate mutated cases. Grey boxes mark unavailable data. <i>FLT3-ITD</i> mutations are indicated with top-half solid boxes and <i>FLT3-TKD</i> with bottom-half solid boxes. Similarly, <i>IDH2-R140Q</i> mutations are shown with top-half solid boxes and <i>IDH2-R172K</i> with bottom-half solid boxes.</p