Propuesta de Supply Chain Management y Logística para la empresa Cotecmar

En un entorno empresarial cada vez más competitivo y globalizado, la gestión eficiente de la cadena de suministro y la logística se han convertido en elementos cruciales para el éxito de una organización. Una empresa que ha reconocido la importancia de optimizar sus operaciones logísticas es COTECMAR, una reconocida empresa dedicada a la industria naval y de defensa en Colombia. COTECMAR ha demostrado un compromiso constante con la innovación y la mejora continua en sus procesos. Sin embargo, para mantener su posición de liderazgo en el mercado y seguir brindando productos y servicios de alta calidad a sus clientes, es fundamental que la empresa tenga una estrategia integral de Supply Chain Management y logística. La implementación de un enfoque estratégico en la gestión de la cadena de suministro permitirá a COTECMAR optimizar la coordinación de todas las actividades relacionadas con el flujo de materiales, información y dinero, desde la adquisición de materias primas hasta la entrega final de los productos terminados. Además, una gestión eficiente de la logística asegurará que los productos sean entregados de manera oportuna, cumpliendo con los requerimientos de los clientes y minimizando los costos asociados al transporte, almacenamiento y distribución. En esta propuesta, se presentarán algunas estrategias clave para mejorar la gestión de la cadena de suministro y la logística de COTECMAR. Estas estrategias incluirán la implementación de tecnologías avanzadas, la optimización de la planificación y el control de inventarios, la colaboración con proveedores y socios logísticos, así como la implementación de prácticas sostenibles y responsables con el medio ambiente.In an increasingly competitive and globalized business environment, efficient supply chain and logistics management have become crucial elements for the success of an organization. A company that has recognized the importance of optimizing its logistics operations is COTECMAR, a renowned company dedicated to the naval and defense industry in Colombia. COTECMAR has demonstrated a constant commitment to innovation and continuous improvement in its processes. However, to maintain its leadership position in the market and continue to provide high-quality products and services to its customers, it is critical that the company have a comprehensive Supply Chain Management and logistics strategy. The implementation of a strategic approach in supply chain management will allow COTECMAR to optimize the coordination of all activities related to the flow of materials, information and money, from the acquisition of raw materials to the final delivery of finished products. In addition, efficient logistics management will ensure that products are delivered in a timely manner, meeting customer requirements and minimizing costs associated with transportation, storage, and distribution. In this proposal, some key strategies will be presented to improve COTECMAR's supply chain and logistics management. These strategies will include the implementation of advanced technologies, optimization of inventory planning and control, collaboration with suppliers and logistics partners, as well as the implementation of sustainable and environmentally responsible practices

Delayed colorectal cancer care during covid-19 pandemic (decor-19). Global perspective from an international survey

Background The widespread nature of coronavirus disease 2019 (COVID-19) has been unprecedented. We sought to analyze its global impact with a survey on colorectal cancer (CRC) care during the pandemic. Methods The impact of COVID-19 on preoperative assessment, elective surgery, and postoperative management of CRC patients was explored by a 35-item survey, which was distributed worldwide to members of surgical societies with an interest in CRC care. Respondents were divided into two comparator groups: 1) ‘delay’ group: CRC care affected by the pandemic; 2) ‘no delay’ group: unaltered CRC practice. Results A total of 1,051 respondents from 84 countries completed the survey. No substantial differences in demographics were found between the ‘delay’ (745, 70.9%) and ‘no delay’ (306, 29.1%) groups. Suspension of multidisciplinary team meetings, staff members quarantined or relocated to COVID-19 units, units fully dedicated to COVID-19 care, personal protective equipment not readily available were factors significantly associated to delays in endoscopy, radiology, surgery, histopathology and prolonged chemoradiation therapy-to-surgery intervals. In the ‘delay’ group, 48.9% of respondents reported a change in the initial surgical plan and 26.3% reported a shift from elective to urgent operations. Recovery of CRC care was associated with the status of the outbreak. Practicing in COVID-free units, no change in operative slots and staff members not relocated to COVID-19 units were statistically associated with unaltered CRC care in the ‘no delay’ group, while the geographical distribution was not. Conclusions Global changes in diagnostic and therapeutic CRC practices were evident. Changes were associated with differences in health-care delivery systems, hospital’s preparedness, resources availability, and local COVID-19 prevalence rather than geographical factors. Strategic planning is required to optimize CRC care

International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care–associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line–associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U.S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN

Coronal Heating as Determined by the Solar Flare Frequency Distribution Obtained by Aggregating Case Studies

Flare frequency distributions represent a key approach to addressing one of the largest problems in solar and stellar physics: determining the mechanism that counter-intuitively heats coronae to temperatures that are orders of magnitude hotter than the corresponding photospheres. It is widely accepted that the magnetic field is responsible for the heating, but there are two competing mechanisms that could explain it: nanoflares or Alfv\'en waves. To date, neither can be directly observed. Nanoflares are, by definition, extremely small, but their aggregate energy release could represent a substantial heating mechanism, presuming they are sufficiently abundant. One way to test this presumption is via the flare frequency distribution, which describes how often flares of various energies occur. If the slope of the power law fitting the flare frequency distribution is above a critical threshold, $\alpha=2$ as established in prior literature, then there should be a sufficient abundance of nanoflares to explain coronal heating. We performed $>$600 case studies of solar flares, made possible by an unprecedented number of data analysts via three semesters of an undergraduate physics laboratory course. This allowed us to include two crucial, but nontrivial, analysis methods: pre-flare baseline subtraction and computation of the flare energy, which requires determining flare start and stop times. We aggregated the results of these analyses into a statistical study to determine that $\alpha = 1.63 \pm 0.03$. This is below the critical threshold, suggesting that Alfv\'en waves are an important driver of coronal heating.Comment: 1,002 authors, 14 pages, 4 figures, 3 tables, published by The Astrophysical Journal on 2023-05-09, volume 948, page 7