35 research outputs found

    Somatosensory evoked potentials as an objective assessment of the sensory median nerve blockade after infraclavicular block

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    Purpose: Median nerve somatosensory evoked responses (MnSSER) alterations were compared to clinical tests (cold and pinprick) variations, in 20 ASA I adult patients following infraclavicular block obtained with 40 mL ropivacaine 0.5% to assess first, the difference of time course of the respective electrophysiological and clinical signs, and second, the objectivity and the reproducibility of MnSSER changes. Clinical features: Four MnSSER derivations (Erb's point; cutaneous projection of peripheral end of brachial plexus; posterior neck at C6 level, frontal and controlateral parietal scalp) were monitored and recorded for retrospective analysis. Continuous data acquisition were started before ropivacaine injection (baseline) and maintained for 30 min thereafter. Every three minutes after ropivacaine injection, cold and pinprick tests were performed in the hand median nerve cutaneous supply zone and were assessed using a sensory visual score (varying from 0-10). Data were compared using analysis of variance. Although MnSSER values were stable during baseline period, after ropivacaine administration, severe progressive amplitude depressions of selected MnSSER were detected in every patient. While clinical cold and pinprick tests became positive (score > 8) only 15.8 ± 1.2 min and 20.1 ± 1.8 min respectively after ropivacaine administration, the mean time to observe the earliest MnSSER 20% amplitude decrease at Erb's point derivation was reduced to 5.6 ± 1.1 min (P < 0.01). Conclusion: Selected MnSSER amplitude reduction indicates objectively the onset of median nerve anesthesia following infraclavicular brachial plexus block before the appearance of clinical sign

    Recherche communautaire sur la sécurité dans les charbonnages et les mines de fer 1962-1966

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    info:eu-repo/semantics/publishe

    Myoglobinemia and propofol infusion [4]

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    SCOPUS: le.jFLWINinfo:eu-repo/semantics/publishe

    Safety of parecoxib and valdecoxib after noncardiac surgery: Lack of demonstration [5]

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    SCOPUS: le.jinfo:eu-repo/semantics/publishe

    DĂ©terminants motivationnels et satisfaction au travail

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    Rapport final d'une recherche relative à l'analyse du travail d'agents de l'Agence Bruxelles-Propreté, Région de Bruxelles-Capitaleinfo:eu-repo/semantics/publishe

    How much does pharmacologic prophylaxis reduce postoperative vomiting in children? Calculation of prophylaxis effectiveness and expected incidence of vomiting under treatment using Bayesian Meta-analysis

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    BACKGROUND: The authors calculated the effect size for treatments recommended for the pediatric population in the new Guidelines for the Management of Postoperative Nausea and Vomiting that should be implemented with the help of a new risk scale developed for children. METHODS: Six single-drug therapies and five combination treatments were subjected to a Bayesian analysis, with respect to the outcome reported, in a sequence that parallels their dates of publication. Based on the Bayes theorem, a posterior probability was calculated after inclusion of the data from the successive studies, to update a prior probability existing before inclusion of that study. The posterior for the preceding group of trials served as the prior for the subsequent trial. The final odds ratio with its 95% credibility interval compared with placebo is considered as the results for that treatment, and was transformed into a relative risk whose 95% credibility interval allows the calculation of a most pessimistic and a most optimistic incidence of postoperative vomiting. RESULTS: The most pessimistic expectations with the 5-hydroxytryptamine receptor antagonists and dexamethasone result in a 50-60% relative risk reduction. The results with droperidol offer a decrease of only approximately 40%. With the combinations of a 5-hydroxytryptamine receptor antagonist and dexamethasone, a relative risk reduction of approximately 80% is expected. CONCLUSIONS: The authors' tables list the expected incidence of postoperative vomiting with each treatment for each risk category, and the expected relative risks that can be used with baseline risk values from any source. © 2008, the American Society of Anesthesiologists, Inc.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
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