Assessment and Management of Scabies in Primary Care Settings

Scabies is an overlooked tropical illness that yet has significant worldwide effects and lasting health repercussions. The condition is caused by the mite Sarcoptes scabei var. hominis, which is a parasitic organism that dwells on the outer layer of the human skin. Scabies is prevalent in impoverished neighborhoods as a result of the high population density in locations such as nursing homes, correctional facilities, and among homeless and displaced children. Nevertheless, modern nations are also prone to scabies infestations, particularly in cases of institutional outbreaks or mini epidemics occurring after conflict or natural calamities. Scabies diagnosis can be aided by both invasive and noninvasive techniques. This paper reviews assessment diagnosis, and management of scabies in primary health care settings

Heat Stroke in Emergency Department: Diagnosis and Management

Background: Heat stroke is a severe health concern with the potential for multi-organ failure, necessitating rapid and effective management. With rising global temperatures, there is increasing concern regarding the vulnerability of populations in high-heat areas, notably in Saudi Arabia, especially during the annual Hajj pilgrimage. Objective: This paper aims to review the epidemiology, evaluation and management techniques of heat stroke, emphasizing the situation during Hajj pilgrimages in Saudi Arabia, and to outline the best practices for emergency management. Methodology: A comprehensive review of literature and studies related to heat stroke, both globally and specific to Saudi Arabia, was undertaken. An in-depth analysis of emergency management, including initial assessment, cooling methods, organ support, medication, and prevention strategies, was conducted. Results: Heat stroke remains a significant cause of emergency department visits, with specific groups, such as men and the elderly, being more susceptible. During the Hajj in 2016, 267 patients were diagnosed with heat-related illnesses, with heatstroke accounting for 29% of these cases. With the threat of global warming, studies indicate a potential tenfold increase in heat stroke risk with a 2°C rise in temperatures. Swift and comprehensive cooling is pivotal for recovery. Management emphasizes rapid recognition, assessment, and varied cooling methods, along with targeted treatments for organ dysfunctions. Prevention strategies play a vital role, given the higher efficacy and practicality over treating organ dysfunctions. Conclusion: Heat stroke is a pressing health challenge, particularly in high-risk environments like Saudi Arabia during the Hajj pilgrimage. While effective emergency management protocols exist, an emphasis on prevention is crucial. It is imperative to incorporate a comprehensive approach to address both the immediate threat and long-term risks of heat stroke, especially with the looming challenge of global warming

Implantable collamer lens for the correction of post-keratoplasty myopia and astigmatism

AIM: To evaluate the safety, refractive outcomes and vision after phakic posterior chamber implantable collamer lens(ICL)after keratoplasty(KP).METHODS: This retrospective single center study evaluated 32(35 eyes)patients who received an ICL for myopia and/or astigmatism after keratoplasty. Patients underwent ICL surgery if they were unable to wear glasses or contact lenses and excimer laser surgery was contraindicated. Data were collected on uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA), refraction and complications. Data were analyzed for the preoperative and last postoperative visits(16.7±13mo)(PRESULTS: Preoperatively, spherical equivalent(SE)ranged from -4.00 to -20.00 D and cylinder from -2.00 to -9.00 D. The mean SE decreased statistically significantly from -11.41±3.62 D preoperatively to -1.95±1.78 D postoperatively(PPCONCLUSION: Posterior chamber phakic intraocular lens implantation is a safe and effective treatment for post-keratoplasty myopia and astigmatism in patients who are unable to wear spectacles or contact lenses and where corneal refractive surgery is contraindicated

Optimization through the Levenberg—Marquardt Backpropagation Method for a Magnetohydrodynamic Squeezing Flow System

The present study introduced the unsteady squeezing flow of two-dimensional viscous fluid with nanoparticles between two disks by using the Levenberg–Marquardt backpropagated neural network (LMB-NN). Conversion of the partial differential equations (PDEs) into equivalent ordinary differential equations (ODEs) is performed by suitable similarity transformation. The data collection for suggested (LMB-NN) is made for various magnetohydrodynamic squeezing flow (MHDSF) scenarios in terms of the squeezing parameter, Prandtl number, Brownian motion parameter, and the thermophoresis parameter by employing the Runge–Kutta technique with the help of Mathematica software. The worth of the proposed methodology has been established for the proposed solver (LMB-NN) with different scenarios and cases, and the outcomes are compared through the effectiveness and reliability of mean square error (MSE) for the squeezing flow problem MHDSF. Moreover, the state transition, Fitness outline, histogram error, and regression presentation also endorse the strength and reliability of the solver LMB-NN. The high convergence between the reference solutions and the solutions obtained by incorporating the efficacy of a designed solver LMB-NN indicates the strength of the proposed methodology, where the accuracy level is achieved in the ranges from 10−6 to 10−12

Management of Diabetes Insipidus following Surgery for Pituitary and Suprasellar Tumors

Central diabetes insipidus (CDI) is a common complication of pituitary surgery. However, it is most frequently transient. It is defined by the excretion of an abnormally large volume of dilute urine with increasing serum osmolality. The reported incidence of CDI after pituitary surgery is variable; ranging from 0-90 %. Large tumor size, gross total resection, and intraoperative cerebrospinal fluid (CSF) leak usually have an increased risk of CDI as also seen with craniopharyngioma and Rathke’s cleft cysts. It can be associated with high morbidities and mortality if not promptly recognized and treated on time. It is essential to rule out other causes of postoperative polyuria to avoid unnecessary pharmacotherapy and iatrogenic hyponatremia. Once the diagnosis of CDI is established, close monitoring is required to evaluate the response to treatment and to determine whether the CDI is transient or permanent. This review outlines the evaluation and management of patients with CDI after pituitary and suprasellar tumors surgery to help recognize the diagnosis, consider the differential diagnosis, initiate therapeutic interventions, guide monitoring, and long-term management. Keywords: Central diabetes insipidus (CDI), polydipsia, polyuria, pituitary adenoma, preoperative risk factor, and pituitary surgery, arginine vasopressin, desmopressin, and treatment

Photocatalytic and Antibacterial Activity of CoFe₂O₄ Nanoparticles from <i>Hibiscus rosa-sinensis</i> Plant Extract

Biogenic CoFe2O4 nanoparticles were prepared by co-precipitation and Hibiscus rosa sinensis plant leaf was used as a bio-reductant of the nanoparticle productions. The biosynthesized CoFe2O4 nanoparticles were characterized by XRD, FTIR, UV, VSM, and SEM via EDX analysis. The cubic phase of biosynthesized CoFe2O4 nanoparticles and their crystallite size was determined by XRD. The Co-Fe-O bonding and cation displacement was confirmed by FTIR spectroscopy. The presence of spherically-shaped biosynthesized CoFe2O4 nanoparticles and their material were confirmed by SEM and TEM via EDX. The super-paramagnetic behaviour of the biosynthesized CoFe2O4 nanoparticles and magnetic pulse was established by VSM analysis. Organic and bacterial pollutants were eradicated using the biosynthesized CoFe2O4 nanoparticles. The spinel ferrite biosynthesized CoFe2O4 nanoparticles generate radical and superoxide ions, which degrade toxic organic and bacterial pollutants in the environment

Gap coupled symmetric split ring resonator based near zero index ENG metamaterial for gain improvement of monopole antenna

In this article, a symmetric split ring resonator (SRR) based metamaterial (MTM) is presented that exhibits three resonances of transmission coefficient (S21) covering S, C, and X-bands with epsilon negative (ENG) and near zero index properties. The proposed MTM is designed on an FR4 substrate with the copper resonator at one side formed with two square rings and one circular split ring. The two square rings are coupled together around the split gap of the outer ring, whereas two split semicircles are also coupled together near the split gaps. Thus, gap coupled symmetric SRR is formed, which helps to obtain resonances at 2.78 GHz, 7.7 GHz and 10.16 GHz with desired properties of the MTM unit cell. The MTM unit cell's symmetric nature helps reduce the mutual coupling effect among the array elements. Thus, different array of unit cells provides a similar response to the unit cell compared with numerical simulation performed in CST microwave studio and validated by measurement. The equivalent circuit is modelled for the proposed MTM unit cell in Advanced Design System (ADS) software, and circuit validation is accomplished by comparing S21 obtained in ADS with the same of CST. The effective medium ratio (EMR) of 10.7 indicates the compactness of the proposed MTM. A test antenna is designed to observe the effect of the MTM over it. Numerical analysis shows that the proposed MTM have an impact on the antenna when it is used as the superstrate and helps to increase the gain of the antenna by 95% with increased directivity. Thus, compact size, high EMR, negative permittivity, near zero permeability and refractive index makes this MTM suitable for S, C and X band applications, especially for antenna gain with directivity enhancement

Synthesis and Characterization with Computational Studies of Metal Complexes of Methyl 2-((4-cyanophenyl)(hydroxy) methyl)acrylate: A New Biologically Active Multi-Functional Adduct

The title ligand (L&rdquo;x), methyl 2-((4-cyanophenyl)(hydroxy)methyl)acrylate was synthesized following the Morita-Baylis-Hillman reaction scheme. Spectroscopic techniques such as: UV- Visible, FT-IR, ESI-MS, and 1H NMR helped in characterization of the L&rdquo;x. Complexes of Cr3+, Co3+, Ni2+, Mn2+, Cu2+ with L&rdquo;x were prepared and characterized by UV- Visible, FT-IR and powder-XRD. FTIR spectrum of the L&rdquo;x generated through DFT B3LYP method and 6-311++ G (d,p) basis set was found in good agreement with experimental spectrum. Additionally, the semi-empirical PM6 method optimization helped propose the most suitable geometries of the complexes with Cr3+, Co3+ possessing octahedral, Ni2+ square planner, Mn2+ and Cu2+ tetrahedral geometries. Powder-XRD patterns of the complexes have revealed cubic crystal class for Cr3+ and Co3+, whereas hexagonal, orthorhombic, and monoclinic for Ni2+, Mn2+, and Cu2+ complexes were observed, respectively. In addition, the nano-particle size was found in the range of 8.2560&ndash;4.5316 nm for complexes. Antibacterial activity against S. aureus, E. coli, B. pumilis and S. typhi confirmed a substantially high potential, as endorsed by their Molecular docking studies, of Ni2+ and Cu2+ complexes against each bacterial strain. Moreover, all compounds exhibited positive antioxidant activities, but have no antifungal potential except L&rdquo;x. The current study demonstrates the usefulness of these novel transition metal complexes as possible potent antibacterial and antioxidant agents

The outright regarding abdominal wall hernia among adults in Jazan: A cross-sectional study

Background: Hernias are repeatedly encountered in surgical clinics owing to risks such as constipation, weightlifting, gestation, weight gain, and ongoing ailments similar to bronchial asthma and prostatic enlargement. The study intended to examine various viewpoints of the population's knowledge and beliefs concerning hernia and its management. Methods: Individuals in this cross-sectional study were randomly picked from those at greater risk of acquiring abdominal wall hernias (AWHs). To report their awareness levels toward AWH, the data were calculated as frequency, expressed as a percentage, and displayed as tables and figures. Results: Eighty-six percent of the patients did not have a hernia during the study, but all had experienced hernias before the study date. About 36.9% of participants showed a poor level of knowledge regarding AWHs. Participants' knowledge was notably correlated with gender, age, marital status, previous abdominal surgery, presence of interfamilial hernias, and having asthma or chronic cough (P < 0.05). According to 55% of respondents, pain and discomfort after an operation are the most prevalent complications, while 15.1% reported no postoperative complications. According to 41.4% of respondents, laparoscopic surgery was the best treatment option, followed by open surgery and lifestyle modifications in 28% and 24.8%, respectively. Conclusion: Compared to females, males were more likely to suffer from AWHs. Hernia's risk factors, management methods, and surgical complications were not well understood by participants. This may entail holding seminars to raise awareness of AWHs among the community members