403 research outputs found
Mediating Political and Social Conflicts: The Skokie-Nazi Dispute
In 1978, a mediation team from the Community Relations Service [CRS] of the United States Department of Justice attempted to mediate the dispute between residents of Skokie, the predominantly Jewish suburb of Chicago and the Nazi party members of the National Socialists Party of America. This dispute involved a number of issues of legal and legislative significance. After a series of complicated negotiations, the Nazis canceled the Skokie demonstration
Ethical Dilemmas or Benign Neglect
But, the real message of this study is that guidance for mediators facing ethical dilemmas is long past due. The Florida mediators, as might have been anticipated, are encountering a number of ethical problems that are familiar to mediators elsewhere and that are endemic to practicing in this field. But, as Professor Bush suggests, the interviews indicate that some of the problems confronting Florida mediators result from their being placed in the untenable position of not being provided with: (1) sufficient policy and procedural guidelines; or (2) training to competently mediate cases being referred to them
Thermal expansion and elastic anisotropy in single crystal Al2O3 and SiC reinforcements
In single crystal form, SiC and Al2O3 are attractive reinforcing components for high temperature composites. In this study, the axial coefficients of thermal expansion and single crystal elastic constants of SiC and Al2O3 were used to determine their coefficients of thermal expansion and Young's moduli as a function of crystallographic orientation and temperature. SiC and Al2O3 exhibit a strong variation of Young's modulus with orientation; however, their moduli and anisotropies are weak functions of temperature below 1000 C. The coefficients of thermal expansion exhibit significant temperature dependence, and that of the non-cubic Al2O3 is also a function of crystallographic orientation
Application of Advanced Nondestructive Evaluation Techniques for Cylindrical Composite Test Samples
Two nondestructive methods were applied to composite cylinder samples pressurized to failure in order to determine manufacturing quality and monitor damage progression under load. A unique computed tomography (CT) image processing methodology developed at NASA Glenn Research was used to assess the condition of the as-received samples while acoustic emission (AE) monitoring was used to identify both the extent and location of damage within the samples up to failure. Results show the effectiveness of both of these methods in identifying potentially critical fabrication issues and their resulting impact on performance
Strength, Fatigue, and Fracture Toughness of Ti-6Al-4V Liner from a Composite Over-Wrapped Pressure Vessel
It was demonstrated by way of experiment that Composite Over-wrapped Pressure Vessel (COPV) Ti-6Al-4V liner material can sustain the expected service loads and cycles. The experiments were performed as part of investigations on the residual life of COPV tanks being used in Space Shuttle Orbiters. Measured properties included tensile strength, compressive strength, reversed loading cycles to simulate liner proof strains, and cyclic fatigue loading to demonstrate the ability to sustain 1000 cycles after liner buckling. The liner material came from a salvaged 40 in. Columbia (orbiter 102) tank (SN029), and tensile strength measurements were made on both boss-transition (thick) and membrane regions (thin). The average measured yield strength was 131 ksi in the boss-transition and membrane regions, in good agreement with measurements made on 1970 s vintage forged plate stock. However, Young s modulus was 17.4+/-0.3 Msi, somewhat higher than typical handbook values (approx.16 Msi). The fracture toughness, as estimated from a failed fatigue specimen, was 74 ksi/sq in, in reasonable agreement with standardized measurements made on 1970 s vintage forged plate stock. Low cycle fatigue of a buckled test specimen implied that as-imprinted liners can sustain over 4000 load cycles
Lot-to-lot Variability of BN Grades for Space Electric Propulsion Applications
Historically, several grades of hot pressed hexagonal boron nitride have been used for space electric propulsion applications. This study investigates the material properties of a selection of commercially available boron nitride grades including HP, M26, M, BNXX, and Shapal Hi-M. This work complements data which was presented at JANNAF 2018. The grades selected for this study are of interest because their available billet size is sufficient for space electric propulsion. This research investigates a range of material properties, tailored and focused on enhancing performance, reliability, and economics of electric propulsion thrusters. This work builds upon previous efforts by studying lot-to-lot variability of some of the properties of interest. Coefficient of friction, moisture absorption, moisture sensitivity, hot press directionality, flexural strength, compression strength, elastic modulus, thermal conductivity, thermal emissivity, thermal expansion, density, X-ray diffraction phase, microstructure, and chemical composition were all investigated across two lots of materials to help guide the selection of advanced ceramics. Variability between lots is the critical concern of the study
Inhibition of Interferon-Gamma-Stimulated Melanoma Progression by Targeting Neuronal Nitric Oxide Synthase (nNOS)
Interferon-gamma (IFN-γ) is shown to stimulate melanoma development and progression. However, the underlying mechanism has not been completely defined. Our study aimed to determine the role of neuronal nitric oxide synthase (nNOS)-mediated signaling in IFN-γ-stimulated melanoma progression and the anti-melanoma effects of novel nNOS inhibitors. Our study shows that IFN-γ markedly induced the expression levels of nNOS in melanoma cells associated with increased intracellular nitric oxide (NO) levels. Co-treatment with novel nNOS inhibitors effectively alleviated IFN-γ-activated STAT1/3. Further, reverse phase protein array (RPPA) analysis demonstrated that IFN-γ induced the expression of HIF1α, c-Myc, and programmed death-ligand 1 (PD-L1), in contrast to IFN-α. Blocking the nNOS-mediated signaling pathway using nNOS-selective inhibitors was shown to effectively diminish IFN-γ-induced PD-L1 expression in melanoma cells. Using a human melanoma xenograft mouse model, the in vivo studies revealed that IFN-γ increased tumor growth compared to control, which was inhibited by the co-administration of nNOS inhibitor MAC-3-190. Another nNOS inhibitor, HH044, was shown to effectively inhibit in vivo tumor growth and was associated with reduced PD-L1 expression levels in melanoma xenografts. Our study demonstrates the important role of nNOS-mediated NO signaling in IFN-γ-stimulated melanoma progression. Targeting nNOS using highly selective small molecular inhibitors is a unique and effective strategy to improve melanoma treatment
The Adhesion Strength of Impact Ice Measured Using a Modified Lap Joint Test
Numerous methodologies have been utilized to measure the adhesion strength of impact ice, and the data reported in the literature varies significantly from test to test. In order to initiate an investigation to determine the cause of this disparity, a new test methodology has been developed and utilized in the Icing Research Tunnel at the NASA Glenn Research Center. Data was obtained while varying the temperature, test section velocity, and cloud droplet mean volumetric diameter. The first data set acquired using this new test method is presented. New trends demonstrate the effect of annealing ice samples, with temperature being a key variable. Observations during the test and analysis of the results suggest the presence of large residual stresses in the samples
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