Data_Sheet_1_Mediating effect of symptom severity on the relationship between aggression, impulsivity and quality of life outcomes among patients with schizophrenia and related psychoses.pdf

AimsAggression and impulsivity among individuals with schizophrenia have been associated with poor clinical outcomes including worsening of symptoms and substance abuse which have been linked to a lower quality of life (QoL). The current study aimed to look at the mediating effect of symptom severity on the relationship between aggression, impulsivity and QoL among outpatients with schizophrenia and related psychoses in a multi-ethnic Asian population.MethodsData (n = 397) were collected from outpatients seeking treatment at the Institute of Mental Health. The World Health Organization quality of life-BREF (WHOQOL-BREF) scale, the symptoms checklist-90 revised (SCL-90-R), Buss Perry aggression questionnaire (BPAQ), and the Barratt impulsiveness scales (BIS) were used to assess subjective well-being, symptom severity, aggression, and impulsivity, respectively. Mediation analysis was performed using the PROCESS macro to understand the mediating effect of symptom severity.ResultsMotor impulsivity (MI) was indirectly associated with both the physical and psychological health domains of QoL while self-control was indirectly associated with the physical, psychological, and environmental health QoL domains through increased symptom severity.ConclusionThe significant indirect effect of symptom severity in our study highlights one potential pathway through which impulsivity impacts the QoL of individuals with schizophrenia and related psychoses. Elucidating other factors besides symptom severity that have an indirect effect on the QoL of individuals provides alternative approaches for treatment through which better clinical outcomes can be achieved.</p

Additional file 1: Table S1. of Body mass index, waist-hip ratio and risk of chronic medical condition in the elderly population: results from the Well-being of the Singapore Elderly (WiSE) Study

Factors associated with missing data. Examination of missing data mechanisms which suggests missing not at random (MNAR). (DOCX 17 kb

Attitudes to Mental Illness and Its Demographic Correlates among General Population in Singapore

<div><p>Background</p><p>Public attitudes to mental illness could influence how the public interact with, provide opportunities for, and help people with mental illness.</p><p>Aims</p><p>This study aims to explore the underlying factors of the Attitudes to Mental Illness questionnaire among the general population in Singapore and the socio-demographic correlates of each factor.</p><p>Methods</p><p>From March 2014 to April 2015, a nation-wide cross-sectional survey on mental health literacy with 3,006 participants was conducted in Singapore.</p><p>Results</p><p>Factor analysis revealed a 4-factor structure for the Attitudes to Mental Illness questionnaire among the Singapore general population, namely social distancing, tolerance/support for community care, social restrictiveness, and prejudice and misconception. Older age, male gender, lower education and socio-economic status were associated with more negative attitudes towards the mentally ill. Chinese showed more negative attitudes than Indians and Malays (except for prejudice and misconception).</p><p>Conclusions</p><p>There is a need for culture-specific interventions, and the associated factors identified in this study should be considered for future attitude campaigns.</p></div

Socio-demographic correlates of Attitudes to Mental Illness questionnaire.

<p>Socio-demographic correlates of Attitudes to Mental Illness questionnaire.</p

Socio-demographic characteristics of the study participants.

<p>Socio-demographic characteristics of the study participants.</p

Factor loadings from EFA analysis on Attitudes to Mental Illness questionnaire (n = 1,503).

<p>Factor loadings from EFA analysis on Attitudes to Mental Illness questionnaire (n = 1,503).</p