Catastrophic secondary antiphospholipid syndrome with peripheral nervous system involvement: a case report.

A 34-year-old woman was admitted to our emergency room with a high fever, abdominal pain, dyspnea and confusion. High fever and abdominal pain had first occured after a cystocele operation 5 months earlier. Later, congestive heart failure with mural thrombus formation, peripheral polyneuropathy and ischemic cerebrovascular accident were identified in clinical follow-ups, and multiple arterial and venous thromboses were seen on cranial and abdominal magnetic resonance imaging angiography. The patient's symptoms improved with anticoagulant treatment. Antiphospholipid syndrome with elevated serum anticardiolipin IgG levels was diagnosed, and ischemic peripheral polyneuropathy with axonal degeneration was determined by sural nerve biopsy. In antiphospholipid syndrome, elevated anticardiolipin antibodies appear to be the most common acquired blood protein defect causing thrombosis. Disseminated vascular thrombosis in catastrophic antiphospholipid syndrome can result in multiorgan failure with increased morbidity and mortality. It rarely occurs secondary to various infections as in the case of our patient, who suffered postoperative intraabdominal infection. It is important to note that peripheral nervous system involvement is rare in antiphospholipid syndrome.</p

Logical Classification of Carbs of Mind Boggling in a Biomolecule

International audienc

Techniques which generally used to concentrate on Protein Design and Capability Incorporate Immunohistochemistry

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Quintic B-spline Collocation Method for Numerical Solutions of the RLW Equation

Quintic B-spline collocation schemes for numerical solution of the regularized long wave (RLW) equation have been proposed. The schemes are based on the Crank–Nicolson formulation for time integration and quintic B-spline functions for space integration. The quintic B-spline collocation method over finite intervals is also applied to the time-split RLW equation and space-split RLW equation. After stability analysis is applied to all the schemes, the results of the three algorithms are compared by studying the propagation of the solitary wave, interaction of two solitary waves and wave undulation. doi:10.1017/S144618110800007

Metastatic Gastric Melanoma: A Challenging Diagnosis

Background. The stomach is regarded as a rare site for metastasis. When a gastric mass is observed macroscopically, the presumed diagnosis is usually a primary gastric carcinoma. However, the stomach may be involved in metastatic malignant melanoma. Besides a possible macroscopical misdiagnosis, metastatic gastric melanoma may also be misdiagnosed microscopically as adenocarcinoma due to its protean histological characteristics. These features make metastatic gastric melanoma a challenging diagnosis in some cases