1,345 research outputs found
Assessment of Design Procedures for Vertical Borehole Heat Exchangers
The use of ground source energy systems is a well-established method to provide low cost heating to buildings, diversify the energy mix and help meeting increasingly stricter sustainability targets. However, considerable uncertainties remain over their efficient design, with several standards, guidelines and manuals being proposed over the last few years. This paper aims at providing insight into the implications to the design of a vertical borehole heat exchanger of the adoption of different design procedures. The hypothetical case of a typical dwelling located in London, UK, is analysed in order to highlight the impact on the final design of the chosen methodology. Moreover, a parametric study using an analytical design procedure was performed to point out the influence of various factors, such as borehole characteristics and thermal properties of the ground. It is shown that there are considerable discrepancies between design methods and that uncertainties in some input parameters, such as the thermal properties of the ground, which for relatively small systems are often selected from tables rather than measured in situ, may have a substantial influence on the length of borehole required
Modelling workplace contact networks: the effects of organizational structure, architecture, and reporting errors on epidemic predictions
Face-to-face social contacts are potentially important transmission routes
for acute respiratory infections, and understanding the contact network can
improve our ability to predict, contain, and control epidemics. Although
workplaces are important settings for infectious disease transmission, few
studies have collected workplace contact data and estimated workplace contact
networks. We use contact diaries, architectural distance measures, and
institutional structures to estimate social contact networks within a Swiss
research institute. Some contact reports were inconsistent, indicating
reporting errors. We adjust for this with a latent variable model, jointly
estimating the true (unobserved) network of contacts and duration-specific
reporting probabilities. We find that contact probability decreases with
distance, and research group membership, role, and shared projects are strongly
predictive of contact patterns. Estimated reporting probabilities were low only
for 0-5 minute contacts. Adjusting for reporting error changed the estimate of
the duration distribution, but did not change the estimates of covariate
effects and had little effect on epidemic predictions. Our epidemic simulation
study indicates that inclusion of network structure based on architectural and
organizational structure data can improve the accuracy of epidemic forecasting
models.Comment: 36 pages, 4 figure
Blow Flies (Calliphoridae) in Alaska
Several blow fly collections were made in the vicinity of Fairbanks between May 28 and June 14, 1948, and one large collection at Anchorage on August 9, 1948. All flies were caught in screen-wire fly traps baited with liver or dead salmon. The material was identified by D. G. Hall, Bureau of Entomology and Plant Quarantine, who also generously provided information concerning the possible importance of the various species of Alaskan blow flie
"The Drier the Land, The Higher the Chance?: An Examination of the Relationship Between Water Availability and Civil Conflict and Its U.S. National Security Implications"
This thesis uses quantitative and qualitative methods to examine the relationship between water availability and civil conflict through an ethnic conflict lens. It further applies the trends observed in this relationship to United States National Security concerns to provide real-world applications of the knowledge gained. Consisting of quantitative and qualitative parts, this thesis uses logit analysis of data to test for significance in the water-conflict relationship then conducts a case study on Israel and Palestine, Darfur, and ISIS in Iraq to examine how water impacts conflict in true situations.
This thesis posits that increased measures of ethnic divisiveness, monopolization of power, autocratic rule, and shorter period of peace will inform the relationship that greater supply, demand, or structurally induced water scarcity will increase the likelihood of violent or nonviolent conflict onset. Although no reliable significant relationships were found, this result indicates that water is more likely an indirect contributor to conflict through the social processes it initiates than a consistently measurable cause of conflict. Through the case studies, this thesis finds that hydrological factors, lack of adaptation ability to environmental changes, information problems, and social processes triggered by water issues are indications that water may be contributing to conflict potential in real cases.
Therefore, this thesis concludes that although statistical relationships between water scarcity and conflict outcomes eluded the analysis, there are observable instances in which water issues contributed indirectly to creating conditions favorable for conflict. In terms of United States national security interests, this conclusion necessitates that in order to predict and prevent water-related insecurity and instability, it is essential that the United States take initiative to promote knowledge of future environmental changes, their impacts on water and social stability, and effective adaptations for unclear future conditions
A practical method for calculating thermally-induced stresses in pile foundations used as heat exchangers
Thermo-active piles are capable of providing both structural stability as foundations and low carbon heating and cooling as ground source heat exchangers. When subjected to heating or cooling, the soil surrounding the pile restricts its expansion or contraction, giving rise to thermally-induced axial stresses, which need to be considered during design. Previous numerical studies often assume axisymmetry of the problem and/or a simplification of the heating or cooling mechanism of the pile. To simulate accurately the development of thermallyinduced axial stresses, this paper presents a computational study comprising three dimensional fully coupled thermo-hydro-mechanical finite element analyses conducted using the Imperial College Finite Element Program (ICFEP), where the heating of a thermo-active pile is simulated by prescribing a flow of hot water through the heat exchanger pipes within the pile. The effects of pipe arrangement on thermally-induced axial stresses are investigated by considering three different cases – single U loop, double U-loop and triple U-loop. Since threedimensional analyses are computationally expensive, a simplified method using a combination of two-dimensional analyses is proposed to estimate the thermally-induced axial stresses, which is subsequently validated and shown to yield accurate results
The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models
Activation of the epidermal growth factor receptor (EGFR) signaling pathway promotes the development of hepatocellular adenoma (HCA) and carcinoma (HCC). The selective EGFR inhibitor Gefitinib was found to prevent hepatocarcinogenesis in rat cirrhotic livers. Thus, Gefitinib might reduce progression of pre-neoplastic liver lesions to HCC. In short-and long-term experiments, administration of N-Nitrosomorpholine (NNM) or intrahepatic transplantation of pancreatic islets in diabetic (PTx), thyroid follicles in thyroidectomized (TTx) and ovarian fragments in ovariectomized (OTx) rats was conducted for the induction of foci of altered hepatocytes (FAH). Gefitinib was administered for two weeks (20 mg/kg) or three and nine months (10 mg/kg). In NNM-treated rats, Gefitinib administration decreased the amount of FAH when compared to controls. The amount of HCA and HCC was decreased, but development was not prevented. Upon all transplantation models, proliferative activity of FAH was lower after administration of Gefitinib in short-term experiments. Nevertheless, the burden of HCA and HCC was not changed in later stages. Thus, EGFR inhibition by Gefitinib diminishes chemical and hormonal also induced hepatocarcinogenesis in the initiation stage in the non-cirrhotic liver. However, progression to malignant hepatocellular tumors was not prevented, indicating only a limited relevance of the EGFR signaling cascade in later stages of hepatocarcinogenesis
Finite element modelling of heat transfer in ground source energy systems with heat exchanger pipes
Ground source energy systems (GSES) utilise low enthalpy geothermal energy and have been recognised as an efficient means of providing low carbon space heating and cooling. This study focuses on GSES where the exchange of heat between the ground and the building is achieved by circulating a fluid through heat exchanger pipes. Although numerical analysis is a powerful tool for exploring the performance of such systems, simulating the highly advective flows inside the heat exchanger pipes can be problematic. This paper presents an efficient approach for modelling these systems using the finite element method (FEM). The pipes are discretised with line elements and the conductive-advective heat flux along them is solved using the Petrov-Galerkin FEM instead of the conventional Galerkin FEM. Following extensive numerical studies, a modelling approach for simulating heat exchanger pipes, which employs line elements and a special material with enhanced thermal properties, is developed. The modelling approach is then adopted in three-dimensional simulations of two thermal response tests, with an excellent match between the computed and measured temperatures being obtained
Quantum Hall Resistance Overshoot in 2-Dimensional Electron Gases - Theory and Experiment
We present a systematical experimental investigation of an unusual transport
phenomenon observed in two dimensional electron gases in Si/SiGe
heterostructures under integer quantum Hall effect (IQHE) conditions. This
phenomenon emerges under specific experimental conditions and in different
material systems. It is commonly referred to as Hall resistance overshoot,
however, lacks a consistent explanation so far. Based on our experimental
findings we are able to develop a model that accounts for all of our
observations in the framework of a screening theory for the IQHE. Within this
model the origin of the overshoot is attributed to a transport regime where
current is confined to co-existing evanescent incompressible strips of
different filling factors.Comment: 26 pages, 10 figure
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