Heading towards the Safer Highways: an assessment of the Avahan prevention programme among long distance truck drivers in India

<p>Abstract</p> <p>Background</p> <p>Using data from two rounds of a cross-sectional, national-level survey of long-distance truck drivers, this paper examines the extent and trend of sexual risk behavior, prevalence of STI/HIV, and the linkage between exposure to HIV prevention programs and safe sex behavior.</p> <p>Methods</p> <p>Following the time location cluster sampling approach, major transshipment locations covering the bulk of India’s transport volume along four routes, North-East (NE), North-South (NS), North-West (NW) and South-East (SE) were surveyed. First round of the survey was conducted in 2007 (sample size 2066) whereas the second round was undertaken in 2009-2010 (sample size 2085). Long distance truck drivers were interviewed about their sexual behaviors, condom use practices, exposure to different HIV prevention interventions, and tested for HIV, reactive syphilis serology, <it>Neiserria gonorrhoeae</it> and <it>Chlamydia trachomatis.</it> The key variable of this evaluation study - exposure to HIV prevention interventions was divided into three categories - no exposure, less intensive exposure and intensive exposure. Data were analyzed using multiple logistic regression methods to understand the relationship between risk behavior and exposure to intervention and between program exposure and condom use.</p> <p>Results</p> <p>The proportion of truckers exposed to HIV prevention interventions has increased over time with much significant increase in the intensive exposure across all the four routes (NE: from 14.9% to 28%, P < 0.01; NS: from 20.9% to 38.1%; NW: 11.5% to 39.5%, P < 0.01; SE: 4.7% to 9.7%, P <0.05). Overall, the consistent condom use in sex with non-regular female partners too has increased over the time (paid female partners: from 67.1% to 73.2%, P <0.05; non-paid female partners: from 17.9% to 37.1%, P <0.05). At the aggregate level, the proportion tested HIV positive has declined from 3.2% to 2.5% in (p<0.10) and proportion tested positive for Syphilis too has reduced from 3.2% to 1.7% (p<0.05). Truckers who had sex with paid female partners (men at risk) were significantly more likely to get exposed to intensive program (aOR: 2.6, 95%CI 1.9-3.4) as compared to those who did not have sex with paid partners. Truckers who had sex with paid partners and exposed to intervention program were more likely to use condoms consistently (aOR: 2.1, 95% CI 1.2-3.7). The consistent condom use among respondents who travel through states with targeted interventions towards female sex workers was higher than those who travel through states with less intensive program among FSWs.</p> <p>Conclusions</p> <p>These evaluation study results highlight the ability of intensive program to reach truckers who have sex outside marriage with HIV prevention interventions and promote safe sex behaviors among them. Truckers who practice safe sex behaviors with an exposure to intensive program are less likely to suffer from STIs and HIV, which has implications for HIV prevention program with truckers’ population in India and elsewhere. The simultaneous targeted interventions among female sex workers appeared to have contributed to safe sexual practices among truckers.</p

National, regional, and state-level all-cause and cause-specific under-5 mortality in India in 2000-15: a systematic analysis with implications for the Sustainable Development Goals.

BACKGROUND: India had the largest number of under-5 deaths of all countries in 2015, with substantial subnational disparities. We estimated national and subnational all-cause and cause-specific mortality among children younger than 5 years annually in 2000-15 in India to understand progress made and to consider implications for achieving the Sustainable Development Goal (SDG) child survival targets. METHODS: We used a multicause model to estimate cause-specific mortality proportions in neonates and children aged 1-59 months at the state level, with causes of death grouped into pneumonia, diarrhoea, meningitis, injury, measles, congenital abnormalities, preterm birth complications, intrapartum-related events, and other causes. AIDS and malaria were estimated separately. The model was based on verbal autopsy studies representing more than 100 000 neonatal deaths globally and 16 962 deaths among children aged 1-59 months at the subnational level in India. By applying these proportions to all-cause deaths by state, we estimated cause-specific numbers of deaths and mortality rates at the state, regional, and national levels. FINDINGS: In 2015, there were 25·121 million livebirths in India and 1·201 million under-5 deaths (under-5 mortality rate 47·81 per 1000 livebirths). 0·696 million (57·9%) of these deaths occurred in neonates. There were disparities in child mortality across states (from 9·7 deaths [Goa] to 73·1 deaths [Assam] per 1000 livebirths) and regions (from 29·7 deaths [the south] to 63·8 deaths [the northeast] per 1000 livebirths). Overall, the leading causes of under-5 deaths were preterm birth complications (0·330 million [95% uncertainty range 0·279-0·367]; 27·5% of under-5 deaths), pneumonia (0·191 million [0·168-0·219]; 15·9%), and intrapartum-related events (0·139 million [0·116-0·165]; 11·6%), with cause-of-death distributions varying across states and regions. In states with very high under-5 mortality, infectious-disease-related causes (pneumonia and diarrhoea) were among the three leading causes, whereas the three leading causes were all non-communicable in states with very low mortality. Most states had a slower decline in neonatal mortality than in mortality among children aged 1-59 months. Ten major states must accelerate progress to achieve the SDG under-5 mortality target, while 17 are not on track to meet the neonatal mortality target. INTERPRETATION: Efforts to reduce vaccine-preventable deaths and to reduce geographical disparities should continue to maintain progress achieved in 2000-15. Enhanced policies and programmes are needed to accelerate mortality reduction in high-burden states and among neonates to achieve the SDG child survival targets in India by 2030. FUNDING: Bill & Melinda Gates Foundation

Gender Disparity Among Indian Library and Information Science Professionals: a 20-year sample of publications from 1999-2018

Gender disparity is present in many research fields including in Library and Information Science (LIS). This paper studied gender disparity among Indian LIS professionals and measure the intellectual output 20 years. The study reviewed 1,195 publications in the LIS field from 1999 to 2018, determining the gender of the first author. An analysis of the publication list determined the yearly contributions of male and female authors, together with the average distributions, yearly citation rates and other metrics, by gender. Across the whole study period, publications first-authored by men outnumbered those by women. Similarly, overall contributions by men were higher than by women. BM Gupta and M Tripathi were the most prolific male and female authors, respectively. India was the most common keyword used by both first author genders. “Bibliometrics”, “Digital Library”, “Scientometrics”, “Academic Libraries”, “E-resources” and “web 2.0” were the core research areas of both men and women. When journals were divided into national and international scope, articles by men outnumbered those by women on both levels. However, 65% of the articles published by women were in international journals, compared to 58% of the articles published by men (59% overall), suggesting that the quality of work produced by women was comparable to or higher than the quality of work published by men. Consequently, gender parity in Indian LIS publications may be some way off. As such, further research is required to highlight and mitigate the issues experienced by women in academia in order to increase productivity in the LIS field in India

Barriers and opportunities for improving childhood immunization coverage in slums: A qualitative study

There is substantial variability in immunization coverage trends across the globe which can be attributed to a number of factors such as demographic profile, socioeconomic characteristics and political environment. Vaccine preventable diseases contribute to severe disease burden when coverage is low, particularly, in slums. Present qualitative study explored barriers, opportunities, and key facilitators of childhood immunization. This was a community based cross-sectional study conducted in the slum areas of Mumbai, India. Data from the observations of immunization sessions and interviews of end users, healthcare service providers, and influencers were collected and analyzed. Lack of time, poor awareness, fear of adverse event, loss of daily income, and migrant population were some of the major reasons to not get immunized. Also, lack of good behavior of staff was another crucial factor perceived by caretakers as barrier in the immunization. Stakeholders agreed that immunization is a shared responsibility involving community, service providers, and policy makers. There was general consensus that immunization practices have improved over the last few years. However, its positive impact is yet to be fully seen in populations that belong to lower socioeconomic strata, thus warranting additional efforts to improve the immunization coverage in slums. Effective communication, process improvement at various levels, active involvement of communities in the immunization activities, building trust and accountability, and constructive feedback are some of the essential elements to strengthen the immunization program. Strategies to improve immunization services in such settings should be based on interactions with stakeholders and understanding their perspectives. Keywords: Immunization, Vaccine, Vaccination, Slums, Qualitative, Indi

Changing epidemiology of HIV in Mumbai: An application of the Asian epidemic model

Background: Mumbai is one of the most populous and high HIV prevalence cities in India. It has witnessed substantial changes in HIV-risk behaviors and a decline in HIV prevalence among high-risk groups during the past decade. Aim: To examine the changing pattern in the number of new HIV infections by transmission routes in Mumbai during 2000–2017. Methods: We used the Asian Epidemic Model by dividing the adult population (aged 15 and above) into seven subgroups: brothel-based and non-brothel based female sex workers (FSWs), heterosexual clients of FSWs, men who have sex with men/transgendered people (MSM), injecting drug users (IDUs), general women and general men. The MSM subgroup included homosexual and bisexual men. Results: New HIV infections among adults reduced by 86% during 2000–2010. The highest decline was among FSWs and their heterosexual clients (95%–98%), followed by MSM (82%), general women (77%), IDUs (51%) and general men (42%). Most new HIV infections during 2011-2017 are expected to occur among general women (1666) and general men (977) followed by MSM (715). Bisexual men were estimated to contribute about 14% of the new HIV infections among general women in 2010 and this proportion was estimated to increase to 19% in 2017. Discussion: HIV prevention programs for MSM and the general population need to be strengthened. Ensuring early detection of HIV, and higher levels of consistent condom use by HIV-infected men and women are essential to prevent new HIV infections in future

Causes of death among HIV-infected adults registered in selected anti-retroviral therapy centers in north-eastern India

Background: Causes of death related studies in HIV infected population are necessary to devise disease specific preventive interventions at both state and national level HIV programs. This study examines the causes of death among HIV-infected individuals registered at selected Anti-Retroviral Therapy (ART) centers in the era of treatment in north-eastern India. Data and Methods: A retrospective chart review of causes of death was undertaken among HIV-infected patients who were treated between January 2006 and November 2012 at three selected ART centers in Assam, a north-eastern state of India. Reported causes of death were coded as per the guidelines of the International Classification of Diseases (ICD-10) to determine the deaths to standard definitions. Results: Among 5612 HIV-infected patients registered over a period of 71 months, 370 deaths have occurred. Tuberculosis (28%) was the leading cause of death followed by death due to AIDS related complex (11%), wasting syndrome and multiple infections (9% each). Deaths due to selected causes were significantly associated with patient’s use of alcohol, WHO clinical stage, CD4 count at the time of diagnosis, presence of opportunistic infections during treatment and ART adherence. Median survival duration was shortest among patients who had CD4 count \u3c 50 at the start of ART (2.9 months) and patients who had multiple opportunistic infections during treatment (2.5 months). Discussion: Majority (67%) of deaths in our study were due to AIDS-related causes. Tuberculosis has remained the leading cause of death among the HIV patients on ART. Strengthening the linkages and referral between the HIV and TB program will be crucial to reduce the AIDS-related deaths attributed to tuberculosis

Contribution of a large-scale HIV prevention program on condom use by long-distance truck drivers in India: A decomposition analysis

Background: This paper examines the impact of the HIV prevention programme among long-distance truck drivers in promoting consistent condom use with paid female partners in India. Methods: The study utilizes data from two rounds of the Integrated Biological and Behavioural Assess met along National Highways (IBBS-NH), 2007 and 2009–10. Using the time location cluster sampling approach, major transshipment locations covering the bulk of India’s transport volume along four route corridors were surveyed. Long-distance truck drivers were interviewed about their sexual behaviour, condom use practices, and exposure to HIV prevention interventions. Results: Consistent condom use with paid female partners was increased by 11% among long distance truck drivers from round 1 to round 2 (Total increase 11%). Truckers exposed to intensive program exposure were two times more likely to use condom consistently with paid partners (OR 2.1; 95% CI 1.4-3.1; p-value \u3c 0.0001). Out of a total increase in consistent condom use with paid partners, truckers who were exposed to the program contributed 58%. Conclusions: This study results highlight the ability of intensive programs to reach truckers who have sex outside marriage with HIV prevention interventions and promote safe sex practices among them

Assessment of effectiveness of targeted intervention program under national AIDS control program among injecting drug users across India

Background: High HIV prevalence among injecting drug users (IDUs) remains a cause of concern and are considered key drivers of concentrated epidemic in India. The present paper aims to assess the effectiveness of the targeted intervention (TI) program on the risk behaviors among IDUs across regions of India. Materials and Methods: This paper used the data from the integrated biological and behavioral surveillance 2014–2015 among the IDUs in India. Descriptive statistics and propensity score matching analysis was carried out to understand the effectiveness of the TI program on the new needle/syringe used and needle/syringe shared in the last injecting episode by accounting for the covariates. Results: The matched samples estimate, i.e., average treatment effect on treated of new needles/syringe used and shared in the last injecting episode by those who received needles/syringes from peer educator or outreach workers (PE/ORWs) and those who did not receive was 2.8% (confidence interval [CI]: 0.05–5.6) increase in the use of new needles/syringes and 6.5% (CI: −9.7–−3.3) decrease in the needles/syringes shared in last injecting episode indicating that IDUs who received new needles/syringes from PE/ORWs are more likely to use new needle/syringe and less likely to share needle/syringes to those who did not receive needles/syringes. The results vary across the different regions of India. Conclusion: TI program proves to be an effective initiative in the behavior change among IDUs as substantiated by use of new needles/syringes and decreased sharing of needles/syringes. TI program coverage varies from region to region and may further be expanded to accelerate the program services to prevent HIV/AIDS