Outcomes after bilateral implantation of AcrySof IQ PanOptix trifocal intraocular lens: a prospective interventional study

Background: Implantation of multifocal intraocular lenses (IOLs) is becoming increasingly popular for the treatment of visual demands at various distances in patients undergoing phacoemulsification cataract surgery. We aimed to assess the visual performance and rates of photic phenomena, posterior capsule opacification (PCO), and spectacle independence in patients with bilateral implantation of the AcrySof® IQ PanOptix® multifocal IOL model TFNT00 at one and six months postoperatively. Methods: This prospective interventional cohort study included adult patients who underwent uneventful phacoemulsification cataract surgery with bilateral implantation of AcrySof® IQ PanOptix® IOL. Uncorrected and corrected visual acuities at far, intermediate, and near distances were measured preoperatively and at the one- and six-month postoperative follow-up examinations. The rates of photic phenomena, postoperative need for near and distance spectacles, and PCO were also recorded. Results: We included 164 eyes of 82 patients with a male-to-female ratio of 38 (46.3%) to 44 (53.7%) and a mean (standard deviation [SD]) age of 52.37 (7.62) years. There were statistically significant improvements in the visual acuities of both eyes across all distances at the one- and six-month follow-up examinations compared to the preoperative values (all P < 0.001), except for corrected near visual acuity in the right eye (P > 0.05) at six-month. We also detected significant postoperative improvements in visual acuities of both eyes across all distances at the six-month follow-up compared to values at the one-month follow-up (all P < 0.05), except for corrected near visual acuity in the right eye (P > 0.05). The photic phenomenon was reported by 12 (14.6%) of the 82 patients at the six-month postoperative follow-up. Five (6.1%) and eight (9.8%) of the 82 patients reported using spectacles for distance and near, respectively. Additionally, PCO developed in 19 (11.6%) of the 164 included eyes, although it was not clinically significant at six months. Conclusions: The AcrySof® IQ PanOptix® IOL model TFNT00 is recommended for use, given its excellent performance in all ranges of vision, a high rate of spectacle independence, and a good safety profile. Future comparative studies with longer follow-up periods are warranted to verify superiority of its performance over that of other available multifocal IOLs

ODFNet: Using orientation distribution functions to characterize 3D point clouds

Learning new representations of 3D point clouds is an active research area in 3D vision, as the order-invariant point cloud structure still presents challenges to the design of neural network architectures. Recent works explored learning either global or local features or both for point clouds, however none of the earlier methods focused on capturing contextual shape information by analysing local orientation distribution of points. In this paper, we leverage on point orientation distributions around a point in order to obtain an expressive local neighborhood representation for point clouds. We achieve this by dividing the spherical neighborhood of a given point into predefined cone volumes, and statistics inside each volume are used as point features. In this way, a local patch can be represented by not only the selected point's nearest neighbors, but also considering a point density distribution defined along multiple orientations around the point. We are then able to construct an orientation distribution function (ODF) neural network that involves an ODFBlock which relies on mlp (multi-layer perceptron) layers. The new ODFNet model achieves state-of the-art accuracy for object classification on ModelNet40 and ScanObjectNN datasets, and segmentation on ShapeNet S3DIS datasets.Comment: The paper is under consideration at Computer Vision and Image Understandin

In situ thrombosis in pulmonary arterial aneurysms due to Behçet’s disease and efficacy of ımmunosuppressive therapy

BehçetDisease (BD) is a systemic vasculitis characterized by recurrent oral and genital ulcers and uveitis, arthritis, and involvement of the gastrointestinal tract, central nervous system and blood vessels. The aneurysms of the pulmonary arteries, with or without thrombosis, are typical manifestation of BD. We report a case with BD, pulmonary arterial aneurysms(PAA) and in situ thrombosis. We aimed to show the effectiveness of immunosuppressive treatment on in situ thrombosis in a case with PAA and BD

Cardiac thrombi in a patient with protein-C and S deficiencies: a case report

We report a case of multiple mobile intra-cardiac thrombi accompanying recurrent pulmonary embolism that has been successfully treated by fibrinolytic therapy. Control transesophageal echocardiographic examination showed that prolonged thrombolytic treatment completely removed the thrombi. Surgical removal of emboli has been validated but cannot be proposed to all patients since it is a high-risk intervention. Fibrinolysis is generally efficient but exposes the patient to risk of migration of the intra-cavity thrombus, with occasionally deleterious evolution. Systemic thrombolytic therapy is usually recommended if (a) it is not contraindicated and (b) the thrombi are demonstrated in more than one cardiac chamber, entailing a higher risk of surgical intervention. However, the infusion rate and duration of thrombolytic therapy are important determinants of successful and uncomplicated lysis. Low dose and long infusion time should be chosen to avoid fragmentation of the thrombus and related complications. © 2004 Ercan et al; licensee BioMed Central Ltd

Farklı yapıdaki kompozit rezin materyallerinin su emilimi ve suda çözünürlük değerlerinin karşılaştırılması

Purpose: The aim of the study is to investigate the physical speciality of composite resins with the water sorption and solubility test. Material and Method: With this aim, 6 kinds of composites were used like microhybrid (Venus), microfill hybrid (Gradia Direct Anterior), nanofill (Filtek Supreme) and nanohybrid composite resins (Clearfil Majesty Esthetic, Premise, Artemis). 15 samples were prepeared from each group at the standart dimensions. In the water sorption test, samples’ dried weight determined as M1. Samples were waited in pure water at 37 °C for 168 days and weight of samples were estimate with sensitive balance for 7 days period and determined as M2. M2 –M1/V formula were used to get results. In water solubility test samples’ dried weight determined as M1. Samples were waited in pure water at 37 °C for 168 days and weight of samples were estimate with sensitive balance for 7 days period and determined as M3. M3 –M1/V formula were used to get results. Data were analysed with statistically. Results: In this in vitro study; in all tests, nanofill and nanohybrid composites according to micro hybrid and microfill hybrid composites was seen statistical meaningful. Conclusion: At the result, composite resins including metacrylat group or groups, inorganic filling content, filler weight, resin matrix junctional surface affect the physical form. ÖZET Amaç: Kompozit rezinlerin fiziksel özelliklerinin; su absorbsiyonu ve çözünürlük testleri ile araştırılması amaçlanmıştır. Gereç ve yöntem: Bu amaçla klinikte kullanılmakta olan universal(Venus), mikrofil hibrit (Gradia Direct Anterior), nanofil (Filtek Supreme) ve nanohibrit kompozit rezinler (Clearfil Majesty Esthetic, Premise, Artemis) olmak üzere 6 çeşit kompozit kullanılmıştır. Her bir gruptan standart boyutlarda 15 adet örnek hazırlanmıştır. Su absorbsiyon testinde örneklerin kuru ağırlıkları M1 olarak belirlendi. Örnekler 168 gün boyunca 37°C’ de distile suda bekletildi ve 7’şer günlük periyotlarla ağırlıkları hassas terazide ölçüldü ve M2 olarak belirlendikten sonra M2–M1/V formülüne göre sonuçlar mg/mm3 olarak tespit edildi. Çözünürlük testinde örneklerin kuru ağırlıkları M1 olarak belirlendi. Örnekler 168 gün boyunca 37°C’ de distile suda bekletildi ve 7’şer günlük periyotlarla ağırlıkları hassas terazide ölçüldü ve M3 olarak belirlendikten sonra M3–M1/V formülüne göre sonuçlar mg/mm3 olarak tespit edildi. Elde edilen verilerin istatistiksel de4erlendirilmesi yapıldı. Bulgular: Yaptığımız in vitro çalışmadan elde ettiğimiz sonuçlara göre nanofil ve nano hibrit kompozitlerin tüm testlerde universal ve mikrofil hibrit kompozitlere göre istatistiksel olarak anlamlı fark oluşturduğu görülmüştür. Sonuç: Sonuç olarak; kompozit rezinlerin içerdiği metakrilat grup veya grupların, inorganik doldurucu içeriğinin, doldurucu ağırlığının, rezin matriks bağlantı yüzeyinin fiziksel yapıyı etkilediği söylenebilir. Anahtar kelimeler: Kompozit, su emilimi, suda çözünürlü

3D Printed Polycaprolactone/Gelatin/Bacterial Cellulose/Hydroxyapatite Composite Scaffold for Bone Tissue Engineering

Three-dimensional (3D) printing application is a promising method for bone tissue engineering. For enhanced bone tissue regeneration, it is essential to have printable composite materials with appealing properties such as construct porous, mechanical strength, thermal properties, controlled degradation rates, and the presence of bioactive materials. In this study, polycaprolactone (PCL), gelatin (GEL), bacterial cellulose (BC), and different hydroxyapatite (HA) concentrations were used to fabricate a novel PCL/GEL/BC/HA composite scaffold using 3D printing method for bone tissue engineering applications. Pore structure, mechanical, thermal, and chemical analyses were evaluated. 3D scaffolds with an ideal pore size (~300 µm) for use in bone tissue engineering were generated. The addition of both bacterial cellulose (BC) and hydroxyapatite (HA) into PCL/GEL scaffold increased cell proliferation and attachment. PCL/GEL/BC/HA composite scaffolds provide a potential for bone tissue engineering applications

Full-endoscopic removal of third ventricular colloid cysts: technique, results, and limitations

IntroductionColloid cysts (CCs) are rare benign lesions that usually arise from the roof of the third ventricle. They may present with obstructive hydrocephalus and cause sudden death. Treatment options include ventriculoperitoneal shunting, cyst aspiration, and cyst resection microscopically or endoscopically. This study aims to report and discuss the full-endoscopic technique for removing colloid cysts.Materials and methodsA 25°-angled neuroendoscope with an internal working channel diameter of 3.1 mm and a length of 122 mm is used. The authors described the technique of resecting a colloid cyst by a full-endoscopic procedure and evaluated the surgical, clinical, and radiological results.ResultsTwenty-one consecutive patients underwent an operation with a transfrontal full-endoscopic approach. The swiveling technique (grasping the cyst wall and rotational movements) was used for CC resection. Of these patients, 11 were female, and ten were male (mean age, 41 years). The most frequent initial symptom was a headache. The mean cyst diameter was 13.9 mm. Thirteen patients had hydrocephalus at admission, and one needed shunting after cyst resection. Seventeen patients (81%) underwent total resection; 3 (14%), subtotal resection; and 1 (5%), partial resection. There was no mortality; one patient had permanent hemiplegia, and one had meningitis. The mean follow-up period was 14 months.ConclusionEven though microscopic resection of cysts has been widely used as a gold standard, successful endoscopic removal has been described recently with lower complication rates. Applying angled endoscopy with different techniques is essential for total resection. Our study is the first case series to show the outcomes of the swiveling technique with low recurrence and complication rates