<span style="font-size:12.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-IN;mso-fareast-language:EN-IN;mso-bidi-language:AR-SA" lang="EN-IN">Synthesis and antimicrobial activity of 1,3,5- triaryl-10-benzyl-1,2,3,4,6,7,8,9-octahydro-8,8-dimethyl-4,6-dioxo-2-thioxo-5<i style="mso-bidi-font-style:normal">H</i>,10<i>H-</i>pyrimido[<span style="mso-bidi-font-style:italic">4,5-<i>b</i>]quinolines</span></span>

1136-1138A convenient one pot synthesis of some pyrimido[4,5-b]quinoline derivatives 2a-g and 3a-g has been reported by the condensation of 5,5-dimethyl-3-benzylamino-2-cyclohexen-1-one with appropriate arylaldehydes and 1,3-diaryl-2-thiobarbituric acids in methanol and screened for their antimicrobial activity. Some of the compounds show significant activity