76 research outputs found
The TESS Triple-9 Catalog II: a new set of 999 uniformly-vetted exoplanet candidates
The Transiting Exoplanet Survey Satellite (TESS) mission is providing the
scientific community with millions of light curves of stars spread across the
whole sky. Since 2018 the telescope has detected thousands of planet candidates
that need to be meticulously scrutinized before being considered amenable
targets for follow-up programs. We present the second catalog of the Plant
Patrol citizen science project containing 999 uniformly-vetted exoplanet
candidates within the TESS ExoFOP archive. The catalog was produced by fully
exploiting the power of the Citizen Science Planet Patrol project. We vetted
TESS Objects of Interest (TOIs) based on the results of Discovery And Vetting
of Exoplanets DAVE pipeline. We also implemented the Automatic Disposition
Generator, a custom procedure aimed at generating the final classification for
each TOI that was vetted by at least three vetters. The majority of the
candidates in our catalog, TOIs, passed the vetting process and were
labelled as planet candidates. We ruled out candidates as false positives
and flagged as potential false positives. Our final dispositions and
comments for all the planet candidates are provided as a publicly available
supplementary table.Comment: 17 pages, 11 figures, 5 tables. Accepted for publication on MNRA
Mass testing of the JUNO experiment 20-inch PMTs readout electronics
The Jiangmen Underground Neutrino Observatory (JUNO) is a multi-purpose,
large size, liquid scintillator experiment under construction in China. JUNO
will perform leading measurements detecting neutrinos from different sources
(reactor, terrestrial and astrophysical neutrinos) covering a wide energy range
(from 200 keV to several GeV). This paper focuses on the design and development
of a test protocol for the 20-inch PMT underwater readout electronics,
performed in parallel to the mass production line. In a time period of about
ten months, a total number of 6950 electronic boards were tested with an
acceptance yield of 99.1%
Implementation and performances of the IPbus protocol for the JUNO Large-PMT readout electronics
The Jiangmen Underground Neutrino Observatory (JUNO) is a large neutrino
detector currently under construction in China. Thanks to the tight
requirements on its optical and radio-purity properties, it will be able to
perform leading measurements detecting terrestrial and astrophysical neutrinos
in a wide energy range from tens of keV to hundreds of MeV. A key requirement
for the success of the experiment is an unprecedented 3% energy resolution,
guaranteed by its large active mass (20 kton) and the use of more than 20,000
20-inch photo-multiplier tubes (PMTs) acquired by high-speed, high-resolution
sampling electronics located very close to the PMTs. As the Front-End and
Read-Out electronics is expected to continuously run underwater for 30 years, a
reliable readout acquisition system capable of handling the timestamped data
stream coming from the Large-PMTs and permitting to simultaneously monitor and
operate remotely the inaccessible electronics had to be developed. In this
contribution, the firmware and hardware implementation of the IPbus based
readout protocol will be presented, together with the performances measured on
final modules during the mass production of the electronics
Validation and integration tests of the JUNO 20-inch PMTs readout electronics
The Jiangmen Underground Neutrino Observatory (JUNO) is a large neutrino
detector currently under construction in China. JUNO will be able to study the
neutrino mass ordering and to perform leading measurements detecting
terrestrial and astrophysical neutrinos in a wide energy range, spanning from
200 keV to several GeV. Given the ambitious physics goals of JUNO, the
electronic system has to meet specific tight requirements, and a thorough
characterization is required. The present paper describes the tests performed
on the readout modules to measure their performances.Comment: 20 pages, 13 figure
Potential of Core-Collapse Supernova Neutrino Detection at JUNO
JUNO is an underground neutrino observatory under construction in Jiangmen, China. It uses 20kton liquid scintillator as target, which enables it to detect supernova burst neutrinos of a large statistics for the next galactic core-collapse supernova (CCSN) and also pre-supernova neutrinos from the nearby CCSN progenitors. All flavors of supernova burst neutrinos can be detected by JUNO via several interaction channels, including inverse beta decay, elastic scattering on electron and proton, interactions on C12 nuclei, etc. This retains the possibility for JUNO to reconstruct the energy spectra of supernova burst neutrinos of all flavors. The real time monitoring systems based on FPGA and DAQ are under development in JUNO, which allow prompt alert and trigger-less data acquisition of CCSN events. The alert performances of both monitoring systems have been thoroughly studied using simulations. Moreover, once a CCSN is tagged, the system can give fast characterizations, such as directionality and light curve
Detection of the Diffuse Supernova Neutrino Background with JUNO
As an underground multi-purpose neutrino detector with 20 kton liquid scintillator, Jiangmen Underground Neutrino Observatory (JUNO) is competitive with and complementary to the water-Cherenkov detectors on the search for the diffuse supernova neutrino background (DSNB). Typical supernova models predict 2-4 events per year within the optimal observation window in the JUNO detector. The dominant background is from the neutral-current (NC) interaction of atmospheric neutrinos with 12C nuclei, which surpasses the DSNB by more than one order of magnitude. We evaluated the systematic uncertainty of NC background from the spread of a variety of data-driven models and further developed a method to determine NC background within 15\% with {\it{in}} {\it{situ}} measurements after ten years of running. Besides, the NC-like backgrounds can be effectively suppressed by the intrinsic pulse-shape discrimination (PSD) capabilities of liquid scintillators. In this talk, I will present in detail the improvements on NC background uncertainty evaluation, PSD discriminator development, and finally, the potential of DSNB sensitivity in JUNO
Real-time Monitoring for the Next Core-Collapse Supernova in JUNO
Core-collapse supernova (CCSN) is one of the most energetic astrophysical
events in the Universe. The early and prompt detection of neutrinos before
(pre-SN) and during the SN burst is a unique opportunity to realize the
multi-messenger observation of the CCSN events. In this work, we describe the
monitoring concept and present the sensitivity of the system to the pre-SN and
SN neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO), which is
a 20 kton liquid scintillator detector under construction in South China. The
real-time monitoring system is designed with both the prompt monitors on the
electronic board and online monitors at the data acquisition stage, in order to
ensure both the alert speed and alert coverage of progenitor stars. By assuming
a false alert rate of 1 per year, this monitoring system can be sensitive to
the pre-SN neutrinos up to the distance of about 1.6 (0.9) kpc and SN neutrinos
up to about 370 (360) kpc for a progenitor mass of 30 for the case
of normal (inverted) mass ordering. The pointing ability of the CCSN is
evaluated by using the accumulated event anisotropy of the inverse beta decay
interactions from pre-SN or SN neutrinos, which, along with the early alert,
can play important roles for the followup multi-messenger observations of the
next Galactic or nearby extragalactic CCSN.Comment: 24 pages, 9 figure
Case control study to assess the possibility of decrease the risk of osteoradionecrosis in relation to the dose of radiation absorbed by the jaw
Aims: the assessment of the limit dose for the organs at risk in external radiotherapy is a fundamental step to guarantee an optimal risk-benefit ratio. The aim of this study was to assess, through contouring the single dental cavities, the absorbed radiation dose on irradiated alveolar bones during the treatment of cervico-facial tumours, so as to test the correlation between the absorbed dose of radiation at alveolar level and the level of individual surgical risk for osteonecrosis.
Materials andmethods: we selected 45 out of 89 patients on the basis of different exclusion criteria. Nine of these patients showed evidence of osteoradionecrosis. The patients were treated either with 3D conformational radiation therapy (3D-CRT) or with intensity-modulated radiation therapy (IMRT), there after alveolar bones were contoured using
computed axial tomography (CAT scans) carried out following oncological and dental treatment. The dose-volume histograms (DVH) were obtained on the basis of such data, which included those relating to the dental cavities in addition to those inherent to the tumours and the organs at risk. Results: all patients, irrespective of type of treatment, received an average of 60 to 70 grays in 30/35 sittings. The patients treated with IMRT showed higher variation in absorbed radiation dose than those treated with 3D-CRT. The alveolar encirclement allowed the assessment of the absorbed radiation dose, and consequently it also allowed to assess the individual surgical risk for osteonecrosis in patients with head and neck tumours who underwent radiography treatment.
Conclusions: the study of DVH allows the assessment of limit dose and the detection of the areas at greater risk for osteoradionecrosis before dental surgery
Surgical protocol in patients at risk for bisphosphonate osteonecrosis of the jaws: clinical use of serum telopetide CTX in preventive monitoring of surgical risk
Aim: This study investigates the association between cross linked C-terminal telopetide test (CTX) and individual surgical risk of osteonecrosis in patients taking oral bisphosphonates.
Materials and Methods: 32 patients receiving bisphosphonate were treated surgically. Patients were divided into three groups according to type of drug administrated and were subjected to a treatment of oral surgery, such as simple tooth extractions and extraction of all residual teeth of the oral cavity, upon evaluation of CTX values and antibiotic prophylaxis.
Results: Within the sample of 32 patients, 12 patients had been treated with bisphosphonates for several years and none developed osteonecrosis of the jaw upon surgery. As for CTX, patients treated with oral bisphosphonates showed a mean value of serum Ctelopetides of 0.2869 ng/ml. The mean value of CTX did not differ significantly between patients taking oral bisphosphonates and healthy patients not treated with bisphosphonates.
Conclusion: None of the patients subjected to preoperative antibiotic prophylaxis developed osteonecrosis of the jaw after surgery. The pharmacological and surgical protocol tested appeared valid in the prevention of osteonecrosis associated to bisphosphonates
Multiple systemic diseases complicated by bisphosphonate osteonecrosis: a case report
Aims: this work aims at demonstrating that multiple systemic conditions, in association with the development of bisphosphonate associated osteonecrosis of the jaw (ONJ), increase the risk of complications and may lead to hospitalization. For this reason the dental approach to patients with multisystem disease should be carefully managed by a team of specialists.
Case report: a case of mandibular necrosis associated with intake of oral bisphosphonates in a complex systemic context is described. Results and discussion: many different diseases and systemic conditions may draw the line at oral surgery. Multiple treatments (e.g. antithrombotic, calcium channel blockers, diuretics, antibiotics and bisphosphonates) can alter the normal physiological response to tissue healing.
Conclusions: patients taking bisphosphonates for more than three years (i.e. the term over which the risk of ONJ increases according to the literature, in presence of complex systemic situations, need to be carefully managed during the pre-operative, peri-operative and postoperative phases through a synergistic collaboration among different kind of specialists
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