Characterization of silver-kaolinite (AgK): an adsorbent for long-lived 129I species

Bentonite is a preferred buffer and backfill material for deep geological disposal of high-level nuclear waste (HLW). Bentonite does not retain anions by virtue of its negatively charged basal surface. Imparting anion retention ability to bentonite is important to enable the expansive clay to retain long-lived I-129 (iodine-129; half-life = 16 million years) species that may escape from the HLW geological repository. Silver-kaolinite (AgK) material is prepared as an additive to improve the iodide retention capacity of bentonite. The AgK is prepared by heating kaolinite-silver nitrate mix at 400 degrees C to study the kaolinite influence on the transition metal ion when reacting at its dehydroxylation temperature. Thermo gravimetric-Evolved Gas Detection analysis, X-ray diffraction analysis, X-ray photo electron spectroscopy and electron probe micro analysis indicated that silver occurs as AgO/Ag2O surface coating on thermally reacting kaolinite with silver nitrate at 400 degrees C

A Web-based interactive Student Advising system using Java frameworks

The use of open source frameworks and tools has become popular in Java development. These frameworks and tools have core strengths and weaknesses and are selected accordingly for development. Consequently, one of the key issues that developers face is to integrate and configure these tools together. This paper demonstrates the use of popular Java frameworks and tools to develop a Web-based interactive Student Registration and Advising system

A test-bed for the Correlation Center of Digital Services

For an e-business to be successful, companies need to formulate a business strategy, have informative strategic alliances, develop an international system, build a proactive infrastructure, internationalize their model, capture the residual value, exploit the international telecommunications liberalization, homogenize the data structure and globalize human resources. To achieve their objective, businesses need a more integrated automation system to speed up the process of establishing and conducting Internet-based services. In this paper, a component-based prototyping approach is used in developing a generic model and framework for a correlation center that provides entrepreneurs with a tool to quickly build and automate e-commerce linkages, thus enabling companies to establish their businesses over the Internet using a proven methodology

Process Personalization Framework for Service-Driven Enterprises

Service functions and service activities are integral part of enterprises. Although technologies have improved for developing service functions, errors persist in service activities. Noted computer scientist Ramamoorthy describes personalization, customization, and humanization of service functions as an effective approach for reducing error in service activities. This paper argues that current personalization approaches does not effectively address the entire spectrum of service functions. The proposed personalization framework can advance current state of personalization through enabling tools as services and services as tools. We discuss the framework utilizing biological research as a service-driven enterprise example. The proposed framework is based on our enterprise process personalization patent

Recommender Systems For Computer Tailored Health Communications

Presentation on the development of a recommender system for a computer-tailored health communications tool that assists with helping tobacco users to quit smoking. This presentation was part of the retreat mini-symposium entitled: Smartphones, Sensors, and Social Networks: The New Tools of Health Behavior Change

Iodide retention by modified kaolinite in the context of safe disposal of high level nuclear waste

Bentonite clay is identified as potential buffer in deep geological repositories (DGR) that store high level radioactive wastes (HLW) as the expansive clay satisfies the expected mechanical and physicochemical functions of the buffer material. In the deep geological disposal of HLW, iodine-129 is one of the significant nuclides, attributable to its long half-life (half life=1.7×107  years). However, the negative charge on the basal surface of bentonite particles precludes retention of iodide anions. To render the bentonite effective in retaining hazardous iodide species in DGR, improvement of the anion retention capacity of bentonite becomes imperative. The iodide retention capacity of bentonite is improved by admixing 10 and 20% Ag-kaolinite (Ag-K) with bentonite (B) on a dry mass basis. The present study produced Ag-kaolinite by heating silver nitrate-kaolinite mixes at 400°C. Marginal release of iodide retained by Ag-kaolinite occurred under extreme acidic (pH=2.5) and alkaline (pH=12.5) conditions. The swell pressure and iodide retention results of the B-Ag-K specimens bring out that mixing Ag-K with bentonite does not chemically modify the expansive clay; the mixing is physical in nature and Ag-K presence only contributes to iodide retention of the admixture

Genetic region characterization (Gene RECQuest) - software to assist in identification and selection of candidate genes from genomic regions

BACKGROUND: The availability of research platforms like the web tools of the National Center for Biotechnology Information (NCBI) has transformed the time-consuming task of identifying candidate genes from genetic studies to an interactive process where data from a variety of sources are obtained to select likely genes for follow-up. This process presents its own set of challenges, as the genetic researcher has to interact with several tools in a time-intensive, manual, and cumbersome manner. We developed a method and implemented an effective software system to address these challenges by multidisciplinary efforts of professional software developers with domain experts. The method presented in this paper, Gene RECQuest, simplifies the interaction with existing research platforms through the use of advanced integration technologies. FINDINGS: Gene RECQuest is a web-based application that assists in the identification of candidate genes from linkage and association studies using information from Online Mendelian Inheritance in Man (OMIM) and PubMed. To illustrate the utility of Gene RECQuest we used it to identify genes physically located within a linkage region as potential candidate genes for a quantitative trait locus (QTL) for very low density lipoprotein (VLDL) response on chromosome 18. CONCLUSION: Gene RECQuest provides a tool which enables researchers to easily identify and organize literature supporting their own expertise and make informed decisions. It is important to note that Gene RECQuest is a data acquisition and organization software, and not a data analysis method

Share2Quit: Web-Based Peer-Driven Referrals for Smoking Cessation

BACKGROUND: Smoking is the number one preventable cause of death in the United States. Effective Web-assisted tobacco interventions are often underutilized and require new and innovative engagement approaches. Web-based peer-driven chain referrals successfully used outside health care have the potential for increasing the reach of Internet interventions. OBJECTIVE: The objective of our study was to describe the protocol for the development and testing of proactive Web-based chain-referral tools for increasing the access to Decide2Quit.org, a Web-assisted tobacco intervention system. METHODS: We will build and refine proactive chain-referral tools, including email and Facebook referrals. In addition, we will implement respondent-driven sampling (RDS), a controlled chain-referral sampling technique designed to remove inherent biases in chain referrals and obtain a representative sample. We will begin our chain referrals with an initial recruitment of former and current smokers as seeds (initial participants) who will be trained to refer current smokers from their social network using the developed tools. In turn, these newly referred smokers will also be provided the tools to refer other smokers from their social networks. We will model predictors of referral success using sample weights from the RDS to estimate the success of the system in the targeted population. RESULTS: This protocol describes the evaluation of proactive Web-based chain-referral tools, which can be used in tobacco interventions to increase the access to hard-to-reach populations, for promoting smoking cessation. CONCLUSIONS: Share2Quit represents an innovative advancement by capitalizing on naturally occurring technology trends to recruit smokers to Web-assisted tobacco interventions

Mitigation of cromium contamination by copper-ZVI bimetallic particles

Soil and water pollution by chromium is a major environmental concern. While existence of chromium in + 3 state is considered benign, it's presence in the + 6 state poses an environmental concern. Hence reduction of Cr(VI) to Cr(III) is considered as a satisfactory environmental solution to mitigate chromium contamination. The oxidation of a metal substrate can be enhanced by depositing small amount of nobler metal on its surface. The present study hence examines the efficiency of Cr (VI) reduction upon deposition of copper (oxidation potential: −0.34 V) on the surface of (zero valent iron) ZVI (oxidation potential: 0.04 V) particles. Batch experiments and pH and Eh measurements revealed that presence of copper loading on ZVI particles increases the efficiency of Cr(VI) reduction by 11 to 233 % in relation to the uncoated ZVI particles owing to enhanced electron activity and release of hydroxyl ions that converted Cr (VI) to mixed Fe-Cr oxide. The Cr (VI) reduction is accomplished in periods ranging from 60 to 240 min in the batch experiments and obeyed the pseudo first or second order kinetics

Nitric Oxide Manipulation: A Therapeutic Target for Peripheral Arterial Disease?

Peripheral Arterial Disease (PAD) is a cause of significant morbidity and mortality in the Western world. Risk factor modification and endovascular and surgical revascularisation are the main treatment options at present. However, a significant number of patients still require major amputation. There is evidence that nitric oxide (NO) and its endogenous inhibitor asymmetric dimethylarginine (ADMA) play significant roles in the pathophysiology of PAD. This paper reviews experimental work implicating the ADMA-DDAH-NO pathway in PAD, focussing on both the vascular dysfunction and effects within the ischaemic muscle, and examines the potential of manipulating this pathway as a novel adjunct therapy in PAD