Hypo‐collagenesis in photoaged skin predicts response to anti‐aging cosmeceuticals

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98115/1/jocd12037.pd

Photodynamic therapy for acne vulgaris: a randomized, controlled, split-face clinical trial of topical aminolevulinic acid and pulsed dye laser therapy

There remains the need for more effective therapeutic options to treat acne vulgaris. Interest in light-based acne treatments has increased, but few randomized, controlled clinical trials assessing the value of photodynamic therapy (PDT) for acne have been reported.We sought to examine the efficacy of PDT using 5-aminolevulinic acid (ALA) and pulsed dye laser therapy in the treatment of acne.We conducted a randomized, controlled, split-face, single-blind clinical trial of 44 patients with facial acne. Patients were randomized to receive three pulsed dye laser treatments to one side of the face after a 60–90 min ALA application time, while the contralateral side remained untreated and served as a control. Serial blinded lesion counts and global acne severity ratings were performed.Global acne severity ratings improved bilaterally with the improvement noted to be statistically significantly greater in treated skin than in untreated skin. Erythematous macules (remnants of previously active inflammatory lesions) decreased in number in treated skin when compared with control skin and there was a transient but significant decrease in inflammatory papules in treated skin when compared with untreated skin. There were no other statistically significant differences between treated and untreated sides of the face in terms of counts of any subtype of acne lesion. Thirty percent of patients were deemed responders to this treatment with respect to improvement in their inflammatory lesion counts, while only 7% of patients responded in terms of noninflammatory lesion counts.PDT with the treatment regimen employed here may be beneficial for a subgroup of patients with inflammatory acne.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79403/1/j.1473-2165.2010.00483.x.pd

Patient interest in and familiarity with anti‐aging therapies: A survey of the general dermatology clinic population

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/144284/1/jocd12386.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144284/2/jocd12386_am.pd

Mentoring in Literacy Education: A Commentary from Graduate Students, Untenured Professors, and Tenured Professors

This commentary continues a dialogue which began among literacy teacher educators attending an alternative format session about mentoring in the academy at a national conference. Literacy teacher educators participated in an informal discussion centered on the nature of mentoring in the academy for doctoral students, untenured professors, and tenured professors. Doctoral students focused on their changing identities and roles in the academy, their concerns about navigating the political infrastructure of academia, and the importance of assuming a proactive stance towards obtaining mentoring, especially for part-time doctoral students. Untenured professors focused on the ways they were inventing and reinventing themselves within the power and politics of academia and their need for more holistic mentoring during these turbulent times. Tenured professors were able to embed mentoring experiences into their scholarly work and find ways to benefit or learn from mentoring experiences. These mentors also found comfort in more informal mentoring that included self-initiated endeavors centered on mutual interests. Our commentary draws on these discussions as well as the professional literature on mentoring to describe the importance of mutual trust and reciprocity in mentoring throughout all stages of academia with attention to cultural and linguistic diversity

Tension properties of aluminum alloys in the presence of stress-raisers.

The effects of circumferential notches on the fracturing characteristics of 24S-T aluminum-alloy tensile test bars were investigated. Two variations in notch contour, namely, notch radius and notch depth, were studied. In addtion, two different surface conditions. were investigated.NACA TN No. 1830."March 1949."Includes bibliographical references.The effects of circumferential notches on the fracturing characteristics of 24S-T aluminum-alloy tensile test bars were investigated. Two variations in notch contour, namely, notch radius and notch depth, were studied. In addtion, two different surface conditions. were investigated.Mode of access: Internet

Direct Quantitative Comparison of Molecular Responses in Photodamaged Human Skin to Fractionated and Fully Ablative Carbon Dioxide Laser Resurfacing

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94282/1/dsu2518.pd