Correlation of structure and stellar properties of galaxies in Stripe 82

Establishing a correlation (or lack thereof) between the bimodal colour distribution of galaxies and their structural parameters is crucial to understand the origin of bimodality. To achieve that, we have performed 2D mass-based structural decomposition (bulge+disc) of all disc galaxies (total$=$1263) in the Herschel imaging area of the Stripe 82 region using $K_s$ band images from the VICS82 survey. The scaling relations thus derived are found to reflect the internal kinematics and are employed in combination to select an indubitable set of classical and pseudo bulge hosting disc galaxies. The rest of the galaxies ($<20\%$) are marked as discs with "ambiguous" bulges. Pseudo and classical bulge disc galaxies exhibit clear bimodality in terms of all stellar parameters ($M_*$, sSFR, $r-K_s$). All pseudo bulge disc galaxies are blue and star-forming and all classical bulge disc galaxies are red and quiescent with less than $5\%$ digressions. Ambiguous bulge disc galaxies are intermittent to pseudo and classical bulge disc galaxies in the distribution of all structural and stellar parameters. $\Delta$$\langle\mu_{eb}\rangle$ - based on the placement of bulges on the Kormendy relation - is found to be the most efficient single structural indicator of both bulge type and stellar activity. The placement of ambiguous bulge disc galaxies on scaling relations and fundamental plane, in addition to their peculiar stellar properties suggest that they are dominantly a part of the green valley.Comment: Accepted for publication in ApJ, 16 pages, 10 figure

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation

Star-dust geometry main determinant of dust attenuation in galaxies

Analysing a large representative sample of local galaxies (8707), we find that the variation in the shape of their dust attenuation curves is driven primarily by their structure, i.e., distribution of stars (and dust) within them. The attenuation curve for spheroid dominated galaxies, as compared to the disc dominated ones, is nearly twice as steep. Both structural types cover distinct ranges of attenuation slope values. Similar findings are reflected in the case of star-forming and passive galaxies. Spheroids and passive galaxies witness minimal attenuation in the optical compared to UV wavelengths underlining the lack of dusty birth-clouds that define complex star-dust geometry. The distinction in the attenuation properties of spheroids and discs is maintained in each stellar mass range emphasising that structure is the primal cause of variation. However, within a structural group, the attenuation curve becomes shallower with both the increase in total stellar mass and optical depth of the galaxy. Overall, with the extinction curve fixed to be the same for all galaxies, the star-dust geometry emerges to be the prime determinant of the variation in their attenuation properties.Comment: Accepted for publication in MNRAS Letters, 5 pages, 3 figure

COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis

Objective: The objective of this study was to evaluate the pooled estimate of diabetes prevalence in young (50 years) COVID-19 cohorts. Methods: Studies published between December-2019 and March-2020 reporting demographic and clinical characteristics of COVID-19 cases were identified. A total of 11 studies included accounting for 2084 COVID-19 patients. Results: The overall prevalence of diabetes in COVID-19 patients with a mean age>50 years was 13.2%, whereas studies with relatively younger patients (mean age <50 years) had a pooled prevalence of 9.0% Conclusion: The overall prevalence of diabetes in COVID-19 patients was found to be 13.2% with studies including relatively elderly patients showing higher rates of diabetes. The intermingled effects of diabetes with other cardiovascular comorbidities warrant age-specific outcomes data including the impact of ongoing antidiabetic treatment

The evolution of disc galaxies with and without classical bulges since z \ensuremath\sim 1

Establishing the relative role of internally and externally driven mechanisms responsible for disc and bulge growth is essential to understand the evolution of disc galaxies. In this context, we have studied the physical properties of disc galaxies without classical bulges in comparison to those with classical bulges since z~0.9. Using images from the Hubble Space Telescope and Sloan Digital Sky Survey, we have computed both parametric and non-parametric measures, and examined the evolution in size, concentration, stellar mass, effective stellar mass density and asymmetry. We find that both disc galaxies with and without classical bulges have gained more than 50% of their present stellar mass over the last ~8 Gyrs. Also, the increase in disc size is found to be peripheral. While the average total (Petrosian) radius almost doubles from z~0.9 to z~0, the average effective radius undergoes a marginal increase in comparison. Additionally, increase in the density of the inner region is evident through the evolution of both concentration and effective stellar mass density. We find that the asymmetry index falls from higher to lower redshifts, but this is more pronounced for the bulgeless disc sample. Also, asymmetry correlates with the global effective radius, and concentration correlates with the global Sersic index, but better so for higher redshifts only. The substantial increase in mass and size indicates that accretion of external material has been a dominant mode of galaxy growth, where the circumgalactic environment plays a significant role.Comment: 18 pages, 10 figures and 5 tables. Accepted for publication in MNRA