Therapeutic evaluation of homeopathic treatment for canine oral papillomatosis

Aim: A study was conducted to evaluate the ameliorative potential of homeopathic drugs in combination (Sulfur 30C, Thuja 30C, Graphites 30C, and Psorinum 30C) in 16 dogs affected with oral papillomatosis which was not undergone any previous treatment. Materials and Methods: Dogs affected with oral papillomatosis, which have not undergone any initial treatment and fed with a regular diet. Dogs (total=16) were randomly divided into two groups, namely, homeopathic treatment group (n=8) and placebo control group (n=8). Random number table was used for allocation. Homeopathic combination of drugs and placebo drug (distilled water) was administered orally twice daily for 15 days. Clinical evaluation in both groups of dogs was performed by the same investigator throughout the period of study (12 months). Dogs were clinically scored for oral lesions on days 0, 5, 7, 10, 15, 20, 25, 30, 45, 60, 90, 120, and 150 after initiation of treatment. Results: The homeopathic treatment group showed early recovery with a significant reduction in oral lesions reflected by clinical score (p<0.001) in comparison to placebo-treated group. Oral papillomatous lesions regressed in the homeopathic group between 7 and 15 days, whereas regression of papilloma in the placebo group occurred between 90 and 150 days. The homeopathic treated group was observed for 12 months post-treatment period and no recurrence of oral papilloma was observed. Conclusion: The current study proves that the combination of homeopathy drugs aids in fastening the regression of canine oral papilloma and proved to be safe and cost-effective

Fuzzy Wavelet Neural Network with Social Spider Optimization Algorithm for Pattern Recognition in Medical Domain

Providing accurate and accessible diagnoses is an important challenge for global healthcare system. The recently developed artificial intelligence (AI) and machine learning (ML) have emerged as powerful tools for solving medical data classification problems. The current research article presents a new Fuzzy Wavelet Neural Network (FWNN) with Social Spider Optimization (SSO) algorithm to recognize the medical data. The aim of FWNN is to utilize both WNN and Adaptive Fuzzy Neuro Inference System (ANFIS) to increase the convergence rate and achieve better approximation abilities. But a number of parameters should be adjusted in due course. In addition, the fuzzy rules enable the technique to tackle uncertainty, whereas the wavelets contribute to enhancing the accuracy of the input output map. SSO algorithm is applied to optimize the architectural parameters of FWNN model such as learning parameters, weights, dilation, and translation. The application of SSO algorithm helps in determining the hyperparameters of FWNN model during medical diagnosis. This is the novelty of current work and it assists in improving the classification performance. The SSO-FWNN model was experimentally validated using three medical benchmark datasets namely, breast cancer, heart disease, and hepatitis. The outcome of simulations indicates that the SSO-FWNN model achieved maximum outcome on all the applied datasets over existing methods in a significant way

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Not AvailableAim: A study was conducted to evaluate the ameliorative potential of homeopathic drugs in combination (Sulfur 30C, Thuja 30C, Graphites 30C, and Psorinum 30C) in 16 dogs affected with oral papillomatosis which was not undergone any previous treatment. Materials and methods: Dogs affected with oral papillomatosis, which have not undergone any initial treatment and fed with a regular diet. Dogs (total=16) were randomly divided into two groups, namely, homeopathic treatment group (n=8) and placebo control group (n=8). Random number table was used for allocation. Homeopathic combination of drugs and placebo drug (distilled water) was administered orally twice daily for 15 days. Clinical evaluation in both groups of dogs was performed by the same investigator throughout the period of study (12 months). Dogs were clinically scored for oral lesions on days 0, 5, 7, 10, 15, 20, 25, 30, 45, 60, 90, 120, and 150 after initiation of treatment. Results: The homeopathic treatment group showed early recovery with a significant reduction in oral lesions reflected by clinical score (p<0.001) in comparison to placebo-treated group. Oral papillomatous lesions regressed in the homeopathic group between 7 and 15 days, whereas regression of papilloma in the placebo group occurred between 90 and 150 days. The homeopathic treated group was observed for 12 months post-treatment period and no recurrence of oral papilloma was observed. Conclusion: The current study proves that the combination of homeopathy drugs aids in fastening the regression of canine oral papilloma and proved to be safe and cost-effective.Not Availabl