Medical device on dental model.

<p>(A) Splints are almost invisible on the front teeth of the upper and lower jaws. (B) linear increase over the upper posterior molars reduces the chewing area to about one fifth.</p

Changes of eating and hunger at baseline without (w/o) or with (w) the medical device eating a standardised meal.

<p>Changes of eating and hunger at baseline without (w/o) or with (w) the medical device eating a standardised meal.</p

Changes of subjective eating behaviour and quality of life during long-term follow-up.

<p>Changes of subjective eating behaviour and quality of life during long-term follow-up.</p

Changes of body weight of participants during the trial.

<p>(A) Change of body weight of all participants prior (4 to 12 years) to testing the device and at inclusion (baseline). (B) Individual change of body weight for all participants during the trial prior to the study (pre-study), -> indicated first usage of the medical device, Phase I is the time period where patients used the device (4 to 10 weeks), Phase II is the follow-up period, during which the device was no longer used. (C) Average change of body weight for all participants during the trial. Boxplots’ bar are medians, grey area represent 25 to 75 IQR, and whiskers are 5^th to 95^th percentiles. * indicates p <0.05, ** indicates p < 0.005.</p

Flowchart.

<p>Flowchart.</p