43 research outputs found

    The three different phases in the dynamics of chemical reaction networks and their relationship to cancer

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    We investigate the catalytic reactions model used in cell modeling. The reaction kinetic is defined through the energies of different species of molecules following random independent distribution. The related statistical physics model has three phases and these three phases emerged in the dynamics: fast dynamics phase, slow dynamic phase and ultra-slow dynamic phase. The phenomenon we found is a rather general, does not depend on the details of the model. We assume as a hypothesis that the transition between these phases (glassiness degrees) is related to cancer. The imbalance in the rate of processes between key aspects of the cell (gene regulation, protein-protein interaction, metabolical networks) creates a change in the fine tuning between these key aspects, affects the logics of the cell and initiates cancer. It is probable that cancer is a change of phase resulting from increased and deregulated metabolic reactions.Comment: 5 pages, 2 figures, EPL, in pres

    Exact probability distribution functions for Parrondo's games

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    We consider discrete time Brownian ratchet models: Parrondo's games. Using the Fourier transform, we calculate the exact probability distribution functions for both the capital dependent and history dependent Parrondo's games. We find that in some cases there are oscillations near the maximum of the probability distribution, and after many rounds there are two limiting distributions, for the odd and even total number of rounds of gambling. We assume that the solution of the aforementioned models can be applied to portfolio optimization.Comment: 5 pages, 3 figure
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