Local Magnetic Properties of a Monolayer of Mn12 Single Molecule Magnets

The magnetic properties of a monolayer of Mn12 single molecule magnets grafted onto a Si substrate have been investigated using depth-controlled $\beta$-detected nuclear magnetic resonance. A low energy beam of spin polarized radioactive 8Li was used to probe the local static magnetic field distribution near the Mn12 monolayer in the Si substrate. The resonance linewidth varies strongly as a function of implantation depth as a result of the magnetic dipolar fields generated by the Mn12 electronic magnetic moments. The temperature dependence of the linewidth indicates that the magnetic properties of the Mn12 moments in this low dimensional configuration differ from bulk Mn12.Comment: 6 pages, 4 figure

Observation of slow order parameter fluctuations in superconducting films using beta-detected NMR

We report beta-NMR investigations of polarized 8Li implanted in thin Pb and Ag/Nb films. At the critical superconducting temperature, we observe a singular peak in the spin relaxation rate in small longitudinal magnetic fields, which is attributed to fluctuations in the superconducting order parameter. However, the peak is more than an order of magnitude larger than the prediction based on the enhancement of the dynamic electron spin susceptibility by superconducting fluctuations and reflects the presence of unexpected slow fluctuations. Furthermore the fluctuations are rapidly suppressed in a small magnetic field, which may explain why they have not been observed previously with conventional NMR or NQR.Comment: 5 pages, 2 figure

Giant Vortices Below the Surface of NbSe2_2 Detected Using Low Energy β\beta-NMR

A low energy radioactive beam of polarized $^8$Li has been used to observe the vortex lattice near the surface of superconducting NbSe$_2$. The inhomogeneous magnetic field distribution associated with the vortex lattice was measured using depth-resolved $\beta$-detected NMR. Below $T_c$ one observes the characteristic lineshape for a triangular vortex lattice which depends on the magnetic penetration depth and vortex core radius. The size of the vortex core varies strongly with magnetic field. In particular in a low field of 10.8 mT the core radius is much larger than the coherence length. The possible origin of these giant vortices is discussed.Comment: 5 pages, 3 figures. Submitted to Phys. Rev. Let

Vortex lattice disorder in YBCO probed using Beta-NMR

Beta-NMR has been used to study vortex lattice disorder near the surface of the high-Tc superconductor YBCO. The magnetic field distribution from the vortex lattice was detected by implanting a low energy beam of highly polarized 8Li into a thin overlayer of silver on optimally doped, twinned and detwinned YBCO samples. The resonance in Ag broadens significantly below the transition temperature Tc as expected from the emerging field lines of the vortex lattice in YBCO. However, the lineshape is more symmetric and the dependence on the applied magnetic field is much weaker than expected from an ideal vortex lattice, indicating that the vortex density varies across the face of the sample, likely due to pinning at twin boundaries. At low temperatures the broadening from such disorder does not scale with the superfluid density.Comment: 10 pages, 6 figure

Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data

According to publicly available transcriptome datasets, the abundance of Annexin A3 (ANXA3) is robustly increased during the course of sepsis; however, no studies have examined the biological significance or clinical relevance of ANXA3 in this pathology. Here we explored this interpretation gap and identified possible directions for future research. Based on reference transcriptome datasets, we found that ANXA3 expression is restricted to neutrophils, is upregulatedin vitroafter exposure to plasma obtained from septic patients, and is associated with adverse clinical outcomes. Secondly, an increase in ANXA3 transcript abundance was also observedin vivo, in the blood of septic patients in multiple independent studies. ANXA3 is known to mediate calcium-dependent granules-phagosome fusion in support of microbicidal activity in neutrophils. More recent work has also shown that ANXA3 enhances proliferation and survival of tumour cells via a Caspase-3-dependent mechanism. And this same molecule is also known to play a critical role in regulation of apoptotic events in neutrophils. Thus, we posit that during sepsis ANXA3 might either play a beneficial role, by facilitating microbial clearance and resolution of the infection; or a detrimental role, by prolonging neutrophil survival, which is known to contribute to sepsis-mediated organ damage