Potential Health Benefits of Anthocyanins in Oxidative Stress Related Disorders

Anthocyanins are naturally occurring water-soluble plant pigments belonging to the flavonoids chemical class. The red, blue and purple colours of leaves, flowers and fruits of plants confirm that they are rich sources of anthocyanins. Many in vivo and in vitro studies reveal that anthocyanins have different health beneficial effects such as antioxidant, antidiabetic, anti-inflammatory, anti-obesity, antihypertensive and anticancer properties. Major benefits of anthocyanin administration are owing to their potent anti-inflammatory and antioxidant activities. Recent investigations have revealed that anti-inflammatory activities of anthocyanins follow the inhibitory pathways of NFкB-mediated decline of inflammatory cytokines production. Inhibition of the anti-inflammatory pathways also influences the modulation of arteriolar disorders and cardiovascular complications due to anthocyanin administration. Moreover, anthocyanins improve diabetes, obesity and cancer pathology by inhibiting NF-кB-mediated inflammatory pathways. However, considerable variations in activities do exist among structurally diverse anthocyanins. This review appraises the recent literature regarding the health benefits of anthocyanins and their molecular mechanisms in various oxidative stress related pathophysiological conditions

Search for Higgs Boson and Observation of Z Boson through their Decay into a Charm Quark-Antiquark Pair in Boosted Topologies in Proton-Proton Collisions at s\sqrt{s} =13 TeV

A search for the standard model (SM) Higgs boson (H) produced with transverse momentum greater than 450 GeV and decaying to a charm quark-antiquark ($\mathrm{c\bar{c}}$) pair is presented. The search is performed using proton-proton collision data collected at $\sqrt{s}$ = 13 TeV by the CMS experiment at the LHC, corresponding to an integrated luminosity of 138 fb$^{-1}$. Boosted H $\to$$\mathrm{c\bar{c}}$ decay products are reconstructed as a single large-radius jet and identified using a deep neural network charm tagging technique. The method is validated by measuring the Z $\to$$\mathrm{c\bar{c}}$ decay process, which is observed in association with jets at high $p_\mathrm{T}$ for the first time with a signal strength of 1.00 $_{-0.14}^{+0.17}$ (syst) $\pm$ 0.08 (theo) $\pm$ 0.06 (stat), defined as the ratio of the observed process rate to the standard model expectation. The observed (expected) upper limit on $\sigma$(H) $\mathcal{B}$(H $\to$$\mathrm{c\bar{c}}$) is set at 47 (39) times the SM prediction at 95% confidence level

Measurement of the electroweak production of Wγ\gamma in association with two jets in proton-proton collisions at s\sqrt{s} = 13 TeV

A measurement is presented for the electroweak production of a W boson, a photon ($\gamma$), and two jets (j) in proton-proton collisions. The leptonic decay of the W boson is selected by requiring one identified electron or muon and large missing transverse momentum. The two jets are required to have large invariant dijet mass and large separation in pseudorapidity. The measurement is performed with the data collected by the CMS detector at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 138 fb$^{-1}$. The cross section for the electroweak W$\gamma$jj production is 23.5 $^{+4.9}_{-4.7}$ fb, whereas the total cross section for W$\gamma$jj production is 113 $\pm$ 13 fb. Differential cross sections are also measured with the distributions unfolded to the particle level. All results are in agreement with the standard model expectations. Constraints are placed on anomalous quartic gauge couplings (aQGCs) in terms of dimension-8 effective field theory operators. These are the most stringent limits to date on the aQGCs parameters $f_{\mathrm{M},2{-}5}/\Lambda^4$ and $f_{\mathrm{T},6{-}7}/\Lambda^4$.A measurement is presented for the electroweak production of a W boson, a photon (γ), and two jets (j) in proton-proton collisions. The leptonic decay of the W boson is selected by requiring one identified electron or muon and large missing transverse momentum. The two jets are required to have large invariant dijet mass and large separation in pseudorapidity. The measurement is performed with the data collected by the CMS detector at a center-of-mass energy of 13  TeV, corresponding to an integrated luminosity of 138  fb-1. The cross section for the electroweak Wγjj production is 23.5-4.7+4.9  fb, whereas the total cross section for Wγjj production is 113±13  fb. Differential cross sections are also measured with the distributions unfolded to the particle level. All results are in agreement with the standard model expectations. Constraints are placed on anomalous quartic gauge couplings (aQGCs) in terms of dimension-8 effective field theory operators. These are the most stringent limits to date on the aQGCs parameters fM,2–5/Λ4 and fT,6–7/Λ4.A measurement is presented for the electroweak production of a W boson, a photon ($\gamma$), and two jets (j) in proton-proton collisions. The leptonic decay of the W boson is selected by requiring one identified electron or muon and large missing transverse momentum. The two jets are required to have large invariant dijet mass and large separation in pseudorapidity. The measurement is performed with the data collected by the CMS detector at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 138 fb$^{-1}$. The cross section for the electroweak W$\gamma$jj production is 23.5 $^{+4.9}_{-4.7}$ fb, whereas the total cross section for W$\gamma$jj production is 113 $\pm$ 13 fb. Differential cross sections are also measured with the distributions unfolded to the particle level. All results are in agreement with the standard model expectations. Constraints are placed on anomalous quartic gauge couplings (aQGCs) in terms of dimension-8 effective field theory operators. These are the most stringent limits to date on the aQGCs parameters $f_\mathrm{M,2-5}$$/$$\Lambda^4$ and $f_\mathrm{T,6-7}$$/$$\Lambda^4$

Measurement of the differential tt‾\hbox {t}\overline{\hbox {t}} production cross section as a function of the jet mass and extraction of the top quark mass in hadronic decays of boosted top quarks

A measurement of the jet mass distribution in hadronic decays of Lorentz-boosted top quarks is presented. The measurement is performed in the lepton + jets channel of top quark pair production ($\hbox {t}\overline{\hbox {t}}$) events, where the lepton is an electron or muon. The products of the hadronic top quark decay are reconstructed using a single large-radius jet with transverse momentum greater than 400$\,\text {Ge}\hspace{-.08em}\text {V}$. The data were collected with the CMS detector at the LHC in proton-proton collisions and correspond to an integrated luminosity of 138$\,\text {fb}^{-1}$. The differential $\hbox {t}\overline{\hbox {t}}$ production cross section as a function of the jet mass is unfolded to the particle level and is used to extract the top quark mass. The jet mass scale is calibrated using the hadronic W boson decay within the large-radius jet. The uncertainties in the modelling of the final state radiation are reduced by studying angular correlations in the jet substructure. These developments lead to a significant increase in precision, and a top quark mass of $173.06 \pm 0.84\,\text {Ge}\hspace{-.08em}\text {V}$

Measurement of the differential tt‾\hbox {t}\overline{\hbox {t}} production cross section as a function of the jet mass and extraction of the top quark mass in hadronic decays of boosted top quarks

A measurement of the jet mass distribution in hadronic decays of Lorentz-boosted top quarks is presented. The measurement is performed in the lepton+jets channel of top quark pair production ($\mathrm{t} \overline{\mathrm{t}}$) events, where the lepton is an electron or muon. The products of the hadronic top quark decay are reconstructed using a single large-radius jet with transverse momentum greater than 400 GeV. The data were collected with the CMS detector at the LHC in proton-proton collisions and correspond to an integrated luminosity of 138 fb$^{-1}$. The differential $\mathrm{t} \overline{\mathrm{t}}$ production cross section as a function of the jet mass is unfolded to the particle level and is used to extract the top quark mass. The jet mass scale is calibrated using the hadronic W boson decay within the large-radius jet. The uncertainties in the modelling of the final state radiation are reduced by studying angular correlations in the jet substructure. These developments lead to a significant increase in precision, and a top quark mass of 172.76 $\pm$ 0.81 GeV.A measurement of the jet mass distribution in hadronic decays of Lorentz-boosted top quarks is presented. The measurement is performed in the lepton + jets channel of top quark pair production ($\hbox {t}\overline{\hbox {t}}$) events, where the lepton is an electron or muon. The products of the hadronic top quark decay are reconstructed using a single large-radius jet with transverse momentum greater than 400$\,\text {Ge}\hspace{-.08em}\text {V}$. The data were collected with the CMS detector at the LHC in proton-proton collisions and correspond to an integrated luminosity of 138$\,\text {fb}^{-1}$. The differential $\hbox {t}\overline{\hbox {t}}$ production cross section as a function of the jet mass is unfolded to the particle level and is used to extract the top quark mass. The jet mass scale is calibrated using the hadronic W boson decay within the large-radius jet. The uncertainties in the modelling of the final state radiation are reduced by studying angular correlations in the jet substructure. These developments lead to a significant increase in precision, and a top quark mass of $173.06 \pm 0.84\,\text {Ge}\hspace{-.08em}\text {V}$.A measurement of the jet mass distribution in hadronic decays of Lorentz-boosted top quarks is presented. The measurement is performed in the lepton+jets channel of top quark pair production ($\mathrm{t\bar{t}}$) events, where the lepton is an electron or muon. The products of the hadronic top quark decay are reconstructed using a single large-radius jet with transverse momentum greater than 400 GeV. The data were collected with the CMS detector at the LHC in proton-proton collisions and correspond to an integrated luminosity of 138 fb$^{-1}$. The differential $\mathrm{t\bar{t}}$ production cross section as a function of the jet mass is unfolded to the particle level and is used to extract the top quark mass. The jet mass scale is calibrated using the hadronic W boson decay within the large-radius jet. The uncertainties in the modelling of the final state radiation are reduced by studying angular correlations in the jet substructure. These developments lead to a significant increase in precision, and a top quark mass of 173.06 $\pm$ 0.84 GeV