396 research outputs found
Narcissistic Invalid or Heroic Genius?: Metaphors of Two Models of Change-of-Air Treatment for Consumption in the 18th- and 19th-Century England
Affectionless control by the same-sex parents increases dysfunctional attitudes about achievement
AbstractBackgroundThe affectionless control parenting has been associated with depression in recipients. The aim of this study was to examine the effect of this parenting style on dysfunctional attitudes predisposing to depression.MethodsThe subjects were 666 Japanese volunteers. Perceived parental rearing was evaluated by the Parental Bonding Instrument, which has the care and protection subscales. Parental rearing was classified into four types, i.e., optimal parenting (high care/low protection), affectionate constraint (high care/high protection), neglectful parenting (low care/low protection), and affectionless control (low care/high protection). Dysfunctional attitudes were evaluated by the 24-item Dysfunctional Attitude Scale, which has the achievement, dependency and self-control subscales.ResultsMales with paternal affectionless control had higher achievement scores than those with paternal optimal parenting (P=.016). Similarly, females with maternal affectionless control had higher achievement scores than those with maternal optimal parenting (P=.016).ConclusionThe present study suggests that affectionless control by the same-sex parents increases dysfunctional attitudes about achievement
Measuring effective orifice area of bileaflet mechanical valves in patients after aortic valve replacement using phase-contrast cine MR imaging
POSTER PRESENTATION2011 SCMR/Euro CMR Joint Scientific Sessions / Nice, France / 3-6 February 201
Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction
AbstractBackground and objectiveSenescence marker protein 30 (SMP30) is assumed to behave as an anti-aging factor. Recently, we have demonstrated that deficiency of SMP30 exacerbates angiotensin II-induced cardiac hypertrophy, dysfunction and remodeling, suggesting that SMP30 may have a protective role in the heart. Thus, this study aimed to test the hypothesis that up-regulation of SMP30 inhibits cardiac adverse remodeling in response to angiotensin II.MethodsWe generated transgenic mice with cardiac-specific overexpression of SMP30 gene using α-myosin heavy chain promoter. Transgenic mice and wild-type littermate mice were subjected to continuous angiotensin II infusion (800ng/kg/min).ResultsAfter 14days, heart weight and left ventricular weight were lower in transgenic mice than in wild-type mice, although blood pressure was similarly elevated during angiotensin II infusion. Cardiac hypertrophy and diastolic dysfunction in response to angiotensin II were prevented in transgenic mice compared with wild-type mice. The degree of cardiac fibrosis by angiotensin II was lower in transgenic mice than in wild-type mice. Angiotensin II-induced generation of superoxide and subsequent cellular senescence were attenuated in transgenic mouse hearts compared with wild-type mice.ConclusionsCardiac-specific overexpression of SMP30 inhibited angiotensin II-induced cardiac adverse remodeling. SMP30 has a cardio-protective role with anti-oxidative and anti-aging effects and could be a novel therapeutic target to prevent cardiac hypertrophy and remodeling due to hypertension
Arrhythmogenic Activity and Channel Remodeling in Ventricles of Dilated Cardiomyopathy (DCM) Model Mice
Conception of Life Skills Education Program for Children and Family Life Supported by Community: Through the practice of "SEMORI" embroidery experience course for parents and children
This report is a practical report of a “SEMORI” embroidery experience program for parents and children, which was conducted envisioning a community-based family and child life skills education program. Participants in the two programs included 36 children, 30 parents, 31 high school students, and 12 university teachers and students. Most of the children who participated had positive opinions about the program, such as “I had fun” and “I want to do more.” Parents also shared positive feedback, such as “It was good to be able to concentrate” and “It was nice to be able to make it with the children.” As for the changes parents and children felt after participating in the first and the second program, the following answers were obtained: “I became to think strongly about my children,” “I had become more active in housework,” and “The number of conversations between parents and children had increased.” Therefore, the life skills education program could be expected not only to help acquire skills, but also to promote communication between parents and children, and make the former feel positive about childrearing and housework.本研究は,JSPS科研費JP20K02811(代表者 梶山曜子)の助成を受けたものである
Very Low-pressure Hydrocephalus: A New Clinical Entity and Issues of Treatment
Secondary normal pressure hydrocephalus (NPH) frequently occurs after severe head injury and cerebrovascular disease. This condition is usually treated by surgically implanting a cerebrospinal fluid (CSF) shunt with a pressure-setting valve or programmable valve. However, some patients do not respond to the shunt operation. Among these non-responders, we found 7 patients whose pressure-setting shunts were mechanically patent, but were not functioning due to very low intracranial pressure (ICP). In these 7 cases, continuous ICP monitoring indicated low pressure with occasional negative pressure, and the patients\u27 consciousness improved during negative-pressure CSF drainage. We performed shunt revisions with zero setting on-off valves, which raised the mean functional independence measure (FIM) scores from 26 to 62. Four patients in a persistent vegetative state (PVS) regained their ability to communicate and recovered to the level of severely disabled (SD). We propose very low-pressure hydrocephalus (VLPH) as a new clinical entity, and describe the process of diagnosis and treatment
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