Ausência de bacteriófagos líticos para Salmonella Enteritidis em amostras de ambientes avícolas no noroeste do Estado de São Paulo

This study evaluated the presence of lytic bacteriophagues of Salmonella Enteritidis (SE) in farms and slaughterhouses in São Paulo State northwest region. One hundred two samples from vaccinated breeder hens, salmonella-positive poultry, and slaughterhouses were assessed. No lytic bacteriophagues of SE were detected in the samples. We infer that the absence of bacteriophagues may be caused by vaccination against SE and good biosecurity practices in field.El presente estudio evaluó la presencia de bacteriófagos líticos que infectan Salmonella Enteritidis (SE) en granjas y rastros localizados en la región noroeste del Estado de São Paulo. Se analizaron 102 muestras obtenidas en granjas de matrices vacunadas, de pollo de carne con historia de positividad a salmonella y rastros. No fue posible identificar la presencia de bacteriófagos líticos de SE en ninguna de las muestras. Se infiere que la ausencia de bacteriófagos sea consecuencia de la vacunación contra SE y las buenas prácticas de bioseguridad en el campo.Avaliou-se a presença de bacteriófagos líticos para Salmonella Enteritis (SE) em granjas e abatedouros no noroeste do Estado de São Paulo. Analisou-se um total de 102 amostras obtidas de granjas de matrizes vacinadas contra SE, frango de corte com histórico de isolamento de Salmonella spp., e também de abatedouros. Detectou-se a ausência de bacteriófagos líticos para SE em 100% da amostras analisadas. Os achados podem estar relacionados a práticas de biosseguridade no controle de SE, inclusive o uso de vacinação contra SE em matrizes, reduzindo o agente a níveis não detectáveis por este sistema

Ketone bodies as a predictor of prognosis of hepatocellular carcinoma after transcatheter arterial chemoembolization

Objective: Arterial ketone bodies, which reflect liver function, have been investigated. However, the relationship between venous ketone bodies and hepatocellular carcinoma (HCC) is unclear. We investigated whether prognosis of patients with HCC after transcatheter arterial chemoembolization (TACE) was associated with venous blood ketone bodies. Methods: Sixty-eight patients with HCC who underwent TACE were recruited for this study. The venous blood ketone body levels were measured 1 d before (pretreatment) and 7 d after TACE (posttreatment). Skeletal muscle quality was evaluated using the intramuscular adipose tissue content (IMAC). Results: Of the 68 patients, 43 (63.2%) were male, with median age of 73.0 y, and the IMAC was ?0.274 (range ?0.82 to 0.24). The median ketone body levels pre- and posttreatment were 63.0 μmol/L (13?310) and 48.0 μmol/L (8?896), respectively. The cumulative survival rate of patients with total ketone body ratio ([TKBR]: posttreatment/pretreatment total ketone bodies) ?0.2745, odds ratio: 3.958, 95% CI: 1.137?13.779, P = 0.031) that predicted TKBR. TKBR and IMAC were positively correlated (rS = 0.358, P = 0.003). Conclusions: The changes in the venous ketone body were associated with the muscle status and predicted the prognosis of patients with HCC who underwent TACE. The venous ketone bodies could be a new predictor of the prognosis of HCC patients after TACE

ILC Reference Design Report Volume 1 - Executive Summary

The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2s^-1. This report is the Executive Summary (Volume I) of the four volume Reference Design Report. It gives an overview of the physics at the ILC, the accelerator design and value estimate, the detector concepts, and the next steps towards project realization.The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2s^-1. This report is the Executive Summary (Volume I) of the four volume Reference Design Report. It gives an overview of the physics at the ILC, the accelerator design and value estimate, the detector concepts, and the next steps towards project realization

ILC Reference Design Report Volume 4 - Detectors

This report, Volume IV of the International Linear Collider Reference Design Report, describes the detectors which will record and measure the charged and neutral particles produced in the ILC's high energy e+e- collisions. The physics of the ILC, and the environment of the machine-detector interface, pose new challenges for detector design. Several conceptual designs for the detector promise the needed performance, and ongoing detector R&D is addressing the outstanding technological issues. Two such detectors, operating in push-pull mode, perfectly instrument the ILC interaction region, and access the full potential of ILC physics.This report, Volume IV of the International Linear Collider Reference Design Report, describes the detectors which will record and measure the charged and neutral particles produced in the ILC's high energy e+e- collisions. The physics of the ILC, and the environment of the machine-detector interface, pose new challenges for detector design. Several conceptual designs for the detector promise the needed performance, and ongoing detector R&D is addressing the outstanding technological issues. Two such detectors, operating in push-pull mode, perfectly instrument the ILC interaction region, and access the full potential of ILC physics