14 research outputs found
A chemically powered unidirectional rotary molecular motor based on a palladium redox cycle
The conversion of chemical energy to drive directional motion at the molecular level allows biological systems, ranging from subcellular components to whole organisms, to perform a myriad of dynamic functions and respond to changes in the environment. Directional movement has been demonstrated in artificial molecular systems, but the fundamental motif of unidirectional rotary motion along a single-bond rotary axle induced by metal-catalysed transformation of chemical fuels has not been realized, and the challenge is to couple the metal-centred redox processes to stepwise changes in conformation to arrive at a full unidirectional rotary cycle. Here, we present the design of an organopalladium-based motor and the experimental demonstration of a 360° unidirectional rotary cycle using simple chemical fuels. Exploiting fundamental reactivity principles in organometallic chemistry enables control of directional rotation and offers the potential of harnessing the wealth of opportunities offered by transition-metal-based catalytic conversions to drive motion and dynamic functions
Desktop NMR spectroscopy for real-time monitoring of an acetalization reaction in comparison with gas chromatography and NMR at 9.4Â T
A chemically powered unidirectional rotary molecular motor based on a palladium redox cycle
Development of a Microfluidic NMR Device for Rapid and Quantitative Detection of Tumor Markers
Protein-directed synthesis of highly monodispersed, spherical gold nanoparticles and their applications in multidimensional sensing
Microfibres and macroscopic films from the coordination-driven hierarchical self-assembly of cylindrical micelles
Microfluidics in Biotechnology: Quo Vadis
Winkler S, Grünberger A, Bahnemann J. Microfluidics in Biotechnology: Quo Vadis. Advances in biochemical engineering/biotechnology. 2021:1-26.The emerging technique of microfluidics offers new approaches for precisely controlling fluidic conditions on a small scale, while simultaneously facilitating data collection in both high-throughput and quantitative manners. As such, the so-called lab-on-a-chip (LOC) systems have the potential to revolutionize the field of biotechnology. But what needs to happen in order to truly integrate them into routine biotechnological applications? In this chapter, some of the most promising applications of microfluidic technology within the field of biotechnology are surveyed, and a few strategies for overcoming current challenges posed by microfluidic LOC systems are examined. In addition, we also discuss the intensifying trend (across all biotechnology fields) of using point-of-use applications which is being facilitated by new technological achievements