970 research outputs found
Ethmoidal osteoid osteoma with orbital and intracranial extension – a case report
BACKGROUND: Osteoid osteoma is a benign bone neoplasm which is seen in the long bones of appendicular skeleton. It is rarely seen in the cranium. Skull base osteoid osteoma is extremely rare and has been anecdotally reported. CASE PRESENTATION: The authors report a case of a large osteoid osteoma of the ethmoid with intraorbital and intracranial extension in a 33 year old male patient. He presented with loss of vision in the left eye. The intra-cranial extension was excised through a single burr-hole fronto-orbitotomy. The ethmoid and orbital portions were approached and excised through a Weber-Ferguson incision and inferior orbitotomy. Radical excision of the tumor could thus be achieved through a craniofacial approach. CONCLUSION: Although benign and rare, skull base osteoid osteoma can present with neurological deficit due to its mass effect and involvement of vital structures. A multispeciality team approach is advisable in such cases if radical excision is to be achieved. A craniofacial approach made radical single stage excision of this multicompartmental osteoid osteoma possible with an uneventful postoperative period
Writing CFT correlation functions as AdS scattering amplitudes
We explore the Mellin representation of conformal correlation functions
recently proposed by Mack. Examples in the AdS/CFT context reinforce the
analogy between Mellin amplitudes and scattering amplitudes. We conjecture a
simple formula relating the bulk scattering amplitudes to the asymptotic
behavior of Mellin amplitudes and show that previous results on the flat space
limit of AdS follow from our new formula. We find that the Mellin amplitudes
are particularly useful in the case of conformal gauge theories in the planar
limit. In this case, the four point Mellin amplitudes are meromorphic functions
whose poles and their residues are entirely determined by two and three point
functions of single-trace operators. This makes the Mellin amplitudes the ideal
objects to attempt the conformal bootstrap program in higher dimensions.Comment: 23 pages + appendice
The a-theorem and conformal symmetry breaking in holographic RG flows
We study holographic models describing an RG flow between two fixed points
driven by a relevant scalar operator. We show how to introduce a spurion field
to restore Weyl invariance and compute the anomalous contribution to the
generating functional in even dimensional theories. We find that the
coefficient of the anomalous term is proportional to the difference of the
conformal anomalies of the UV and IR fixed points, as expected from anomaly
matching arguments in field theory. For any even dimensions the coefficient is
positive as implied by the holographic a-theorem. For flows corresponding to
spontaneous breaking of conformal invariance, we also compute the two-point
functions of the energy-momentum tensor and the scalar operator and identify
the dilaton mode. Surprisingly we find that in the simplest models with just
one scalar field there is no dilaton pole in the two-point function of the
scalar operator but a stronger singularity. We discuss the possible
implications.Comment: 50 pages. v2: minor changes, added references, extended discussion.
v3: we have clarified some of the calculations and assumptions, results
unchanged. v4: published version in JHE
Modifying the Sum Over Topological Sectors and Constraints on Supergravity
The standard lore about the sum over topological sectors in quantum field
theory is that locality and cluster decomposition uniquely determine the sum
over such sectors, thus leading to the usual theta-vacua. We show that without
changing the local degrees of freedom, a theory can be modified such that the
sum over instantons should be restricted; e.g. one should include only
instanton numbers which are divisible by some integer p. This conclusion about
the configuration space of quantum field theory allows us to carefully
reconsider the quantization of parameters in supergravity. In particular, we
show that FI-terms and nontrivial Kahler forms are quantized. This analysis
also leads to a new derivation of recent results about linearized supergravity.Comment: 17 pages, minor change
Metabolic syndrome in children and adolescents - criteria for diagnosis
In recent years, there has been a greater concern about the presence of obesity and metabolic syndrome in children and adolescents. However, there is no consensus regarding the diagnosis of metabolic syndrome in children and adolescents. It is evident that each component of the syndrome must be identified as early as possible in order to prevent definitive lesions. The question is how to do this and which cut-offs must be adopted for this diagnosis. For a matter of convenience, the definition chosen as the most appropriate is the one proposed by the IDF, with cut-offs fixed for pressure, lipids and glycemia, and abdominal circumference points assessed by percentile. Although on the one hand this definition could fail to include some children in the diagnosis of Metabolic Syndrome, on the other hand, it would be of easier acceptance as it does not use multiple tables to assess several anthropometric and metabolic criteria
Graviton Vertices and the Mapping of Anomalous Correlators to Momentum Space for a General Conformal Field Theory
We investigate the mapping of conformal correlators and of their anomalies
from configuration to momentum space for general dimensions, focusing on the
anomalous correlators , - involving the energy-momentum tensor
with a vector or a scalar operator () - and the 3-graviton vertex
. We compute the , and one-loop vertex functions in
dimensional regularization for free field theories involving conformal scalar,
fermion and vector fields. Since there are only one or two independent tensor
structures solving all the conformal Ward identities for the or
vertex functions respectively, and three independent tensor structures for the
vertex, and the coefficients of these tensors are known for free fields,
it is possible to identify the corresponding tensors in momentum space from the
computation of the correlators for free fields. This works in general
dimensions for and correlators, but only in 4 dimensions for ,
since vector fields are conformal only in . In this way the general
solution of the Ward identities including anomalous ones for these correlators
in (Euclidean) position space, found by Osborn and Petkou is mapped to the
ordinary diagrammatic one in momentum space. We give simplified expressions of
all these correlators in configuration space which are explicitly Fourier
integrable and provide a diagrammatic interpretation of all the contact terms
arising when two or more of the points coincide. We discuss how the anomalies
arise in each approach [...]Comment: 57 pages, 7 figures. Refs adde
Q methodology and a Delphi poll: a useful approach to researching a narrative approach to therapy
Q methodology and a Delphi poll combined qualitative and quantitative methods to explore definitions of White and Epston's (1990) narrative approach to therapy among a group of UK practitioners. A Delphi poll was used to generate statements about narrative therapy. The piloting of statements by the Delphi panel identified agreement about theoretical ideas underpinning narrative therapy and certain key practices. A wider group of practitioners ranked the statements in a Q sort and made qualitative comments about their sorting. Quantitative methods (principal components analysis) were used to extract eight accounts of narrative therapy, five of which are qualitatively analysed in this paper. Agreement and differences were identified across a range of issues, including the social construction of narratives, privileging a political stance or narrative techniques and the relationship with other therapies, specifically systemic psychotherapy. Q methodology, combined with the Delphi poll, was a unique and innovative feature of this study
Scalar Three-point Functions in a CDL Background
Motivated by the FRW-CFT proposal by Freivogel, Sekino, Susskind and Yeh, we
compute the three-point function of a scalar field in a Coleman-De Luccia
instanton background. We first compute the three-point function of the scalar
field making only very mild assumptions about the scalar potential and the
instanton background. We obtain the three-point function for points in the FRW
patch of the CDL instanton and take two interesting limits; the limit where the
three points are near the boundary of the hyperbolic slices of the FRW patch,
and the limit where the three points lie on the past lightcone of the FRW
patch. We expand the past lightcone three-point function in spherical
harmonics. We show that the near boundary limit expansion of the three-point
function of a massless scalar field exhibits conformal structure compatible
with FRW-CFT when the FRW patch is flat. We also compute the three-point
function when the scalar is massive, and explain the obstacles to generalizing
the conjectured field-operator correspondence of massless fields to massive
fields.Comment: 42 pages + appendices, 10 figures; v2, v3: minor correction
The sub-energetic GRB 031203 as a cosmic analogue to GRB 980425
Over the six years since the discovery of the gamma-ray burst GRB 980425,
associated with the nearby (distance, ~40 Mpc) supernova 1998bw, astronomers
have fiercely debated the nature of this event. Relative to bursts located at
cosmological distances, (redshift, z~1), GRB 980425 was under-luminous in
gamma-rays by three orders of magnitude. Radio calorimetry showed the explosion
was sub-energetic by a factor of 10. Here, we report observations of the radio
and X-ray afterglow of the recent z=0.105 GRB 031203 and demonstrate that it
too is sub-energetic. Our result, when taken together with the low gamma-ray
luminosity, suggest that GRB 031203 is the first cosmic analogue to GRB 980425.
We find no evidence that this event was a highly collimated explosion viewed
off-axis. Like GRB 980425, GRB 031203 appears to be an intrinsically
sub-energetic gamma-ray burst. Such sub-energetic events have faint afterglows.
Intensive follow-up of faint bursts with smooth gamma-ray light curves (common
to both GRBs 031203 and 980425) may enable us to reveal their expected large
population.Comment: To Appear in Nature, August 5, 200
Childhood obesity and risk of the adult metabolic syndrome: a systematic review.
This is an Open Access articleBackground: While many studies have demonstrated positive associations between childhood obesity and adult metabolic risk, important questions remain as to the nature of the relationship. In particular, it is unclear whether the associations reflect the tracking of body mass index (BMI) from childhood to adulthood or an independent level of risk. This systematic review aimed to investigate the relationship between childhood obesity and a range of metabolic risk factors during adult life.
Objective: To perform an unbiased systematic review to investigate the association between childhood BMI and risk of developing components of metabolic disease in adulthood, and whether the associations observed are independent of adult BMI.
Design: Electronic databases were searched from inception until July 2010 for studies investigating the association between childhood BMI and adult metabolic risk. Two investigators independently reviewed studies for eligibility according to the inclusion/exclusion criteria, extracted the data and assessed study quality using the Newcastle–Ottawa Scale.
Results: The search process identified 11 articles that fulfilled the inclusion and exclusion criteria. Although several identified weak positive associations between childhood BMI and adult total cholesterol, low-density lipo protein-cholesterol, triglyceride and insulin concentrations, these associations were ameliorated or inversed when adjusted for adult BMI or body fatness. Of the four papers that considered metabolic syndrome as an end point, none showed evidence of an independent association with childhood obesity.
Conclusions: Little evidence was found to support the view that childhood obesity is an independent risk factor for adult blood lipid status, insulin levels, metabolic syndrome or type 2 diabetes. The majority of studies failed to adjust for adult BMI and therefore the associations observed may reflect the tracking of BMI across the lifespan. Interestingly, where adult BMI was adjusted for, the data showed a weak negative association between childhood BMI and metabolic variables, with those at the lower end of the BMI range in childhood, but obese during adulthood at particular risk
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