10 research outputs found

    Outbreak of turkey pox disease in fowl pox vaccinated poults in Vom Plateau State of Nigeria

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    An outbreak of poxvirus infecting 45 turkeys of 8 weeks of age is reported. Poults were previously vaccinated against pox using fowl poX vaccine. The outbreak persisted for 5 weeks with 100% morbidity hut no mortality. The cutaneous form only existed. Turkey pox virus was isolated by propagation in chorioallantoid membrane and confirmed by reproducing the disease in susceptible turkeys. African Journal of Clinical and Experimental Microbiology Vol. 7(2) 2006: 136-13

    Immunoprotectivity of attenuated turkey poxvirus in turkey poults and broiler chicks

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    In Nigeria, fowl pox vaccine is used in all categories of poultry. However there has been reports of outbreak of turkey pox virus in poults previously vaccinated with fowl pox vaccine. Pox Lesion from poults was excised for isolation of virus and viral propagation in chorioallantoid membrane. Turkey pox virus were isolated from the infected turkeys and confirmed by infecting susceptible turkeys with the isolate to reproduce the disease. Persistence of both turkey poults and broiler chickens to challenge after vaccination with attenuated turkey poxvirus was confirmed. African Journal of Clinical and Experimental Microbiology Vol. 7(2) 2006: 98-10

    Introducing a model of cardiovascular prevention in Nairobi's slums by integrating a public health and private-sector approach: the SCALE-UP study

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    Introduction: Cardiovascular disease (CVD) is a leading cause of death in sub-Saharan Africa (SSA), with annual deaths expected to increase to 2 million by 2030. Currently, most national health systems in SSA are not adequately prepared for this epidemic. This is especially so in slum settlements where access to formal healthcare and resources is limited. Objective: To develop and introduce a model of cardiovascular prevention in the slums of Nairobi by integrating public health and private sector approaches. Study design: Two non-profit organizations that conduct public health research, Amsterdam Institute for Global Health and Development (AIGHD) and African Population and Health Research Center (APHRC), collaborated with private-sector Boston Consulting Group (BCG) to develop a service delivery package for CVD prevention in slum settings. A theoretic model was designed based on the integration of public and private sector approaches with the focus on costs and feasibility. Results: The final model includes components that aim to improve community awareness, a home-based screening service, patient and provider incentives to seek and deliver treatment specifically for hypertension, and adherence support. The expected outcomes projected by this model could prove potentially cost effective and affordable (1 USD/person/year). The model is currently being implemented in a Nairobi slum and is closely followed by key stakeholders in Kenya including the Ministry of Health, the World Health Organization (WHO), and leading non-governmental organizations (NGOs). Conclusion: Through the collaboration of public health and private sectors, a theoretically cost-effective model was developed for the prevention of CVD and is currently being implemented in the slums of Nairobi. If results are in line with the theoretical projections and first impressions on the ground, scale-up of the service delivery package could be planned in other poor urban areas in Kenya by relevant policymakers and NGOs

    A feedback loop: Interactions between Inflammatory Signals and Clonal Hematopoiesis in Cardiovascular Disease

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    Fate of Hematopoiesis During Aging. What Do We Really Know, and What are its Implications?

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