Determination of carbon monoxide in blood

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Generative Artificial Intelligence in Information Systems Education: Challenges, Consequences, and Responses

ChatGPT, an interactive, generative artificial intelligence (AI) system, was introduced in late 2022, quickly becoming one of the most rapidly adopted technologies in history. The rapid emergence of ChatGPT and similar AI tools, such as Google’s Bard, and GPT-enabled Bing from Microsoft have led to intense discussions about how they will affect various aspects of society, including higher education. Information systems (IS) education will not escape the impact of AI tools. Our goal for this paper is to develop a better understanding of the range of possible impacts of ChatGPT on IS education and to describe how IS educators might respond to these potential impacts. To that end, we discuss challenges for IS education brought on by generative AI tools, and discuss potential future scenarios based on the emergence of such tools, ranging from AI having little impact on IS education to AI serving as competition for IS educators. We examine the challenges and consequences of each scenario. We also discuss potential responses, ranging from doing nothing to embracing AI tools as legitimate learning aids. We then provide several specific recommendations that will allow IS educators to effectively respond to the rise of AI tools

Michaelis-Menten dynamics in protein subnetworks

To understand the behaviour of complex systems it is often necessary to use models that describe the dynamics of subnetworks. It has previously been established using projection methods that such subnetwork dynamics generically involves memory of the past, and that the memory functions can be calculated explicitly for biochemical reaction networks made up of unary and binary reactions. However, many established network models involve also Michaelis-Menten kinetics, to describe e.g. enzymatic reactions. We show that the projection approach to subnetwork dynamics can be extended to such networks, thus significantly broadening its range of applicability. To derive the extension we construct a larger network that represents enzymes and enzyme complexes explicitly, obtain the projected equations, and finally take the limit of fast enzyme reactions that gives back Michaelis-Menten kinetics. The crucial point is that this limit can be taken in closed form. The outcome is a simple procedure that allows one to obtain a description of subnetwork dynamics, including memory functions, starting directly from any given network of unary, binary and Michaelis-Menten reactions. Numerical tests show that this closed form enzyme elimination gives a much more accurate description of the subnetwork dynamics than the simpler method that represents enzymes explicitly, and is also more efficient computationally