85 research outputs found
Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release
Get PDFAcute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA). Interleukin-1\u3b2 (IL-1\u3b2), a master regulator of neuroinflammation produced by activated inflammatory cells of the myeloid lineage, in particular microglia, plays a key role in the pathogenesis of acute and chronic diseases of the peripheral nervous system and CNS. IL-1\u3b2 release is promoted by ATP acting at the purinergic P2X7 receptor (P2X7R) in cells primed with toll-like receptor (TLR) ligands
Intimate partner violence among undergraduate students of two universities of the state of SĂŁo Paulo, Brazil
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DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample
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Typologies of Childhood Exposure to Violence: Associations With College Student Mental Health
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Assessing programs designed to improve outcomes for children exposed to violence: Results from nine randomized controlled trials
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