32 research outputs found
The predictive value of sonographic images of follicular lesions – a comparison with nodules unequivocal in FNA – single centre prospective study
A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi
Can diffusion-weighted imaging add information in the evaluation of breast lesions considered suspicious on magnetic resonance imaging?
Follicular thyroid carcinoma with predominantly cystic formation presenting initially with multiple distant metastases
Magnetic resonance perfusion and diffusion characteristics of granulomatous diseases mimic those of malignant lesions: six case reports
Atypia of Undetermined Significance in Thyroid Fine-Needle Aspiration Cytology: Prediction of Malignancy by US and Comparison of Methods for Further Management
Incidental thyroid uptake on F-18 FDG PET/CT: correlation with ultrasonography and pathology
Apparent Diffusion Coefficient (ADC) Value: A Potential Imaging Biomarker That Reflects the Biological Features of Rectal Cancer
The near demise and subsequent revival of classical genetics for investigating Caenorhabditis elegans embryogenesis: RNAi meets next-generation DNA sequencing
Molecular genetic investigation of the early Caenorhabditis elegans embryo has contributed substantially to the discovery and general understanding of the genes, pathways, and mechanisms that regulate and execute developmental and cell biological processes. Initially, worm geneticists relied exclusively on a classical genetics approach, isolating mutants with interesting phenotypes after mutagenesis and then determining the identity of the affected genes. Subsequently, the discovery of RNA interference (RNAi) led to a much greater reliance on a reverse genetics approach: reducing the function of known genes with RNAi and then observing the phenotypic consequences. Now the advent of next-generation DNA sequencing technologies and the ensuing ease and affordability of whole-genome sequencing are reviving the use of classical genetics to investigate early C. elegans embryogenesis