Bioactivity And Chemical Composition Of The Essential Oil From The Leaves Of Guatteria Australis A.st.-hil

Essential oil from the leaves of Guatteria australis was obtained by hydrodistillation, analyzed by Gas Chromatography coupled to Mass Spectromery (GC–MS) and their antiproliferative, antileishmanial, antibacterial, antifungal and antioxidant activities were also evaluated. Twenty-three compounds were identified among which germacrene B (50.66%), germacrene D (22.22%) and (E)-caryophyllene (8.99%) were the main compounds. The highest antiproliferative activity was observed against NCI-ADR/RES (TGI = 31.08 μg/ml) and HT-29 (TGI = 32.81 μg/ml) cell lines. It also showed good antileishmanial activity against Leishmania infantum (IC50 = 30.71 μg/ml). On the other hand, the oil exhibited a small effect against Staphylococcus aureus ATCC 6538, S. aureus ATCC 14458 and Escherichia coli ATCC 10799 (MIC = 250 μg/ml), as well as small antioxidant activity (457 μmol TE/g) assessed through ORACFL assay. These results represent the first report regarding chemical composition and bioactivity of G. australis essential oil

Influência dos níveis de concentrado sobre os cortes comerciais, os constituintes não-carcaça e os componentes da perna de cordeiros confinados Effect of concentrate levels on retail cuts, non-carcass and leg components of crossbred feedlot lambs

Um experimento foi realizado com o objetivo de determinar a influência dos níveis de concentrado sobre o peso e o rendimento dos cortes e dos constituintes não-carcaça e a composição tecidual da perna de cordeiros mestiços de Dorper terminados em confinamento ou mestiços de Dorper x Santa Inês. Foram utilizados 32 cordeiros (não-castrados) ½ Dorper x ½ Santa Inês (peso médio inicial de 17,1 kg) alimentados com dietas contendo 30, 45, 60 e 75% de concentrado. Os cordeiros foram distribuídos em um delineamento inteiramente casualizado com quatro tratamentos e oito repetições. Os animais foram mantidos em confinamento durante 43 dias. Após o abate, as carcaças foram resfriadas por 24 horas. Foram registrados os pesos e as porcentagens dos cortes da meia-carcaça e as porcentagens de osso, músculos e tecido adiposo, avaliadas por meio de dissecação da perna. Houve efeito significativo linear crescente dos níveis de concentrado sobre os pesos de pescoço, paleta, costilhar, lombo e perna. Verificou-se também efeito significativo linear decrescente sobre os rendimentos dos cortes comerciais (pescoço, perna e paleta), excetuando-se o de costilhar, que cresceu linearmente. A espessura de gordura e a área de olho-de-lombo foram influenciadas pelos níveis de concentrado. Observou-se efeito significativo sobre os constituintes não-carcaça, exceto o trato digestório, que não foi afetado pelos níveis de concentrado. O aumento do nível de concentrado influenciou o peso e o rendimento dos cortes e órgãos internos e aumentou a proporção e a deposição de gordura na carcaça.<br>Thirty-two intact lambs averaging 17.1 kg of initial body weight were assigned to one of the following four treatments: 30, 45, 60 or 75% of dietary concentrate in a completely randomized design (eight lambs/treatment). Lambs were feedlot fed during the experimental period (43 days). After slaughter, carcasses were refrigerated for 24 h. It was measured the weights and percentages of five cuts from the half carcass as well as the proportion of muscle, bone and fat tissue from the leg. The weights of neck, shoulder, ribs, loin and leg all increased linearly by increasing the level of concentrate in the diet while the opposite was observed for the yields of neck, leg, and shoulder; yield of ribs followed the increment of concentrate in the diet and increased linearly. Fat thickness and loin eye area were both affected by the level of concentrate in the diet. The same was observed for the non-carcass components with the exception of digestive tract. Feeding increasing dietary levels of concentrate to lambs affected the weight and yield of retail cuts and internal organs and increased the proportion and deposition of fat in the carcass