81 research outputs found

    Migration, Racism and the Hostile Environment: Making the Case for the Social Sciences

    Get PDF
    Cite as: Social Scientists Against the Hostile Environment (SSAHE)(2020). Migration, racism and the hostile environment : Making the case for the social sciences. London. https://acssmigration.wordpress.com/report/

    A Root in Synapsis and the Other One in the Gut Microbiome-Brain Axis: Are the Two Poles of Ketogenic Diet Enough to Challenge Glioblastoma?

    Get PDF
    Glioblastoma is the most frequent and aggressive brain cancer in adults. While precision medicine in oncology has produced remarkable progress in several malignancies, treatment of glioblastoma has still limited available options and a dismal prognosis. After first-line treatment with surgery followed by radiochemotherapy based on the 2005 STUPP trial, no significant therapeutic advancements have been registered. While waiting that genomic characterization moves from a prognostic/predictive value into therapeutic applications, practical and easy-to-use approaches are eagerly awaited. Medical reports on the role of the ketogenic diet in adult neurological disorders and in glioblastoma suggest that nutritional interventions may condition outcomes and be associated with standard therapies. The acceptable macronutrient distribution of daily calories in a regular diet are 45–65% of daily calories from carbohydrates, 20–35% from fats, and 10–35% from protein. Basically, the ketogenic diet follows an approach based on low carbohydrates/high fat intake. In carbohydrates starvation, body energy derives from fat storage which is used to produce ketones and act as glucose surrogates. The ketogenic diet has several effects: metabolic interference with glucose and insulin and IGF-1 pathways, influence on neurotransmission, reduction of oxidative stress and inflammation, direct effect on gene expression through epigenetic mechanisms. Apart from these central effects working at the synapsis level, recent evidence also suggests a role for microbiome and gut-brain axis induced by a ketogenic diet. This review focuses on rationales supporting the ketogenic diet and clinical studies will be reported, looking at future possible perspectives

    Effectiveness of service screening: a case–control study to assess breast cancer mortality reduction

    Get PDF
    The aim of this study was the evaluation of the impact of service screening programmes on breast cancer mortality in five regions of Italy. We conducted a matched case–control study with four controls for each case. Cases were defined as breast cancer deaths occurred not later than 31 December 2002. Controls were sampled from the local municipality list and matched by date of birth. Screening histories were assessed by the local, computerised, screening database and subjects were classified as either invited or not-yet-invited and as either screened or unscreened. There were a total of 1750 breast cancer deaths within the 50 to 74-year-old breast cancer cases and a total of 7000 controls. The logistic conditional estimate of the cumulative odds ratios comparing invited with not-yet-invited women was 0.75 (95% CI: 0.62–0.92). Restricting the analyses to invited women, the odds ratio of screened to never-respondent women corrected for self-selection bias was 0.55 (95% CI: 0.36–0.85). The introduction of breast cancer screening programmes in Italy is associated with a reduction in breast cancer mortality attributable to the additional impact of service screening over and above the background access to mammography

    Refugee artists and memories of displacement: a visual semiotics analysis

    Get PDF
    This paper considers the ways in which refugee artists represent the experience of displacement, their cultural traditions and the longing for home through paintings and how, by doing so, they become the visual interpreters of the current refugee crisis. The starting point of this article is that little attention has been paid towards the visual narratives of artworks produced by refugee artists and shared on social media. Through the visual semiotics analysis of 150 images of paintings (exhibited on the Facebook page Syria.Art) and through a number of individual interviews with the artists themselves, the article identifies three emerging visual narratives. These are concerned primarily with reminiscences about people, places and cultural practices lost (or in danger of being lost) because of the forced journey and because of the displacement. Within this context, these visual discourses become part of an open repository, which mediates, re-organises and preserves memories, both personal and collective as a form of emotional survival and resilience. It is argued that these visual narratives and representations nurture empathy for the human condition of the refugees and universalise the migrant experience

    Citizenship, rights, and deservingness:Introduction to the special issue

    No full text
    Over the past few decades, immigration has become a central issue in scholarly and policy debates. While scholarship has worked to uncover underlying mechanisms, the public debate has been too often informed by questions of assimilability and the rule of law drawing distinctions that hold up certain subgroups within a community as deserving and others as undeserving. This introduction to the special issue briefly outlines the theoretical and public debates while describing the articles in the special issue. </jats:p

    An adaptive FEC scheme to reduce bursty losses in a 802.11 network

    No full text
    One of the challenges that video transmission over wireless networks (such as IEEE 802.11) must face is the packet loss that can heavily decrease the received video quality. What makes the challenge more difficult is the bursty nature of wireless losses. Many video decoders can mask the effects of small amounts of random packet loss, however, most are unable to successfully hide the effects of burst losses (periods with high loss data rate). Forward error correction (FEC) is a technique extensively adopted to increase error resilience. In unicast transmission, the FEC redundancy is usually added adaptively on the basis of a loss pattern feedback. In many cases the loss pattern is represented through a very simple statistics: the average packer error rate (PER). This paper proposes a technique to adaptively introduce FEC redundancy that exploits a feedback scheme based on a 4-state Markov model to describe the loss pattern. The model allows us to obtain a description of the loss pattern in terms of burst and gap length and density. The feedback is based on the RTCP extended Report - IP Video Metrics Report Blocks that includes statistics on error patterns, such as the average PER, burst length and density. Our simulation results show that the proposed method smoothes out the burst losses and outperforms solutions based on the average PER. © 2006 IEEE
    • …
    corecore