146 research outputs found

    Investigation of Roll-to-Roll Gravure Printing for Printed Electronics with Fine Features

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    Gravure printing is known to be cost competitive in manufacturing of printed electronic devices due to its capability to mass produce at lower costs. Current standard of gravure printed feature sizes is in a range of around 50 μm down to sub-10 μm, predominantly through small scale setups and specialized engraving. However, reliance on gravure cell design limits the scalability of printing over a large area due to the setup cost. In this study, ink viscoelastic behavior was modified to improve replication of gravure printed features over a large printing area of 300 mm web-width without a reduction in gravure cell dimension. Fine lines were printed using a high viscosity ink with a good replication of the nominal line width. Control over the printed features was performed through the variation of printing speed and the alteration of ink viscosity. The effects of ink viscosity and printing speed on the printed ink particle distribution and size were also examined. New methodologies of characterizing ink transfer were also developed to help understand the ink transfer processes: mass transfer and particle transfer. A deeper understanding of the thixotropic effect and shear recovery behavior of inks was achieved through simulations of shearing conditions

    Stratigraphy and provenance of the Paleogene syn-rift sediments in central-southern Palawan: paleogeographic significance for the South China margin

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    The Palawan microcontinental block is thought to have separated from the South China margin due to seafloor spreading and opening of the South China Sea. However, it is uncertain when and from which section the Palawan microcontinental block rifted from the South China margin, and little is known about sediment routing across the rifted margin before continental breakup. To address these aspects we studied the biostratigraphy and provenance of syn-rift sedimentary rocks collected from the Panas-Pandian Formation in central-southern Palawan. Micropaleontological evidence indicates a Middle Eocene–earliest Oligocene (47.7–32.9 Ma) age for the Panas-Pandian Formation. Based on this and the oldest age of the post-rift Nido Limestone (~32 Ma), the breakup unconformity on the Palawan microcontinent block is dated around 33–32 Ma. This timing of breakup unconformity is close to that of the Pearl River Mouth Basin (~30 Ma) and IODP Site U1435 (~34Ma), suggesting the conjugate relationship between the Palawan microcontinental block and the Pearl River Mouth Basin. Trace fossils and benthic foraminifera from the Panas-Pandian Formation indicate a middle bathyal to abyssal environment on the continental slope of the South China margin. Multidisciplinary provenance analysis reveals that the Panas-Pandian Formation was derived from both local Mesozoic basement uplifts and the interior Cathaysia Block. It indicates that a paleo-Pearl River has been established at least since the Middle Eocene (47.7– 42.1 Ma) and could deliver sediments from the interior Cathaysia Block to the continental slope, across the wide rifted margin with a low topographic gradien

    Development and Characterization of Neutralizing Antibodies Against Zaire Ebolavirus Glycoprotein and Protein 40

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    Background/Aims: Monoclonal antibodies (mAbs) are presently the most promising treatment against Ebola virus disease (EVD), and cocktail of two or more antibodies likely confers protection through complementary mechanisms. Zaire Ebolavirus (EBOV) glycoprotein (GP) and viral protein 40 (VP40) are targets for designing neutralizing antibodies. Currently, the antiviral therapeutics of mAb-cocktails are still limited solely to anti-GP antibodies,there is no Abs cocktail against Zaire EBOV GP and VP40, which both have important interactions with host cellular membrane. Methods: We used hybridoma technology to produce anti-Zaire EBOV GP mAb against GP receptor binding domain, and anti-Zaire EBOV VP40 mAbs against the N-terminal domain, the C-terminal domain, respectively; synthesized Zaire EBOV transcription and replication competent virus like particles (trVLPs), which model even all aspects of the EBOV life cycles in order to evaluate the anti-viral effect of mAbs. Then, we characterized the anti- Zaire EBOV trVLPs effect of anti-GP and VP40 mAbs in vitro by real time-PCR, immunofluorescence assay and western blot analysis. Results: Our results demonstrate that anti-GP or anti-VP40 mAbs effectively inhibit trVLPs replication. The cocktails of anti-GP and anti-VP40 mAbs, or between anti-VP40 mAbs, had synergistic anti-trVLPs effect. Meanwhile, the detailed DNA and amino acid sequences of the mAbs were checked. Conclusion: The study verifies neutralizing efficacy of anti-GP or anti-VP40 mAb, report promising cocktail of anti-GP and anti-VP40 mAb, or cocktail of two anti-VP40 mAbs. To our knowledge, this is the first account to report the important anti-viral effect of cocktails of anti-GP and anti-VP40 mAbs in vitro

    Direct Measurements of the Branching Fractions for D0Ke+νeD^0 \to K^-e^+\nu_e and D0πe+νeD^0 \to \pi^-e^+\nu_e and Determinations of the Form Factors f+K(0)f_{+}^{K}(0) and f+π(0)f^{\pi}_{+}(0)

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    The absolute branching fractions for the decays D0Ke+νeD^0 \to K^-e ^+\nu_e and D0πe+νeD^0 \to \pi^-e^+\nu_e are determined using 7584±198±3417584\pm 198 \pm 341 singly tagged Dˉ0\bar D^0 sample from the data collected around 3.773 GeV with the BES-II detector at the BEPC. In the system recoiling against the singly tagged Dˉ0\bar D^0 meson, 104.0±10.9104.0\pm 10.9 events for D0Ke+νeD^0 \to K^-e ^+\nu_e and 9.0±3.69.0 \pm 3.6 events for D0πe+νeD^0 \to \pi^-e^+\nu_e decays are observed. Those yield the absolute branching fractions to be BF(D0Ke+νe)=(3.82±0.40±0.27)BF(D^0 \to K^-e^+\nu_e)=(3.82 \pm 0.40\pm 0.27)% and BF(D0πe+νe)=(0.33±0.13±0.03)BF(D^0 \to \pi^-e^+\nu_e)=(0.33 \pm 0.13\pm 0.03)%. The vector form factors are determined to be f+K(0)=0.78±0.04±0.03|f^K_+(0)| = 0.78 \pm 0.04 \pm 0.03 and f+π(0)=0.73±0.14±0.06|f^{\pi}_+(0)| = 0.73 \pm 0.14 \pm 0.06. The ratio of the two form factors is measured to be f+π(0)/f+K(0)=0.93±0.19±0.07|f^{\pi}_+(0)/f^K_+(0)|= 0.93 \pm 0.19 \pm 0.07.Comment: 6 pages, 5 figure

    Measurements of J/psi Decays into 2(pi+pi-)eta and 3(pi+pi-)eta

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    Based on a sample of 5.8X 10^7 J/psi events taken with the BESII detector, the branching fractions of J/psi--> 2(pi+pi-)eta and J/psi-->3(pi+pi-)eta are measured for the first time to be (2.26+-0.08+-0.27)X10^{-3} and (7.24+-0.96+-1.11)X10^{-4}, respectively.Comment: 11 pages, 6 figure

    Study of J/ψωK+KJ/\psi \to \omega K^+K^-

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    New data are presented on J/ψωK+KJ/\psi \to \omega K^+K^- from a sample of 58M J/ψJ/\psi events in the upgraded BES II detector at the BEPC. There is a conspicuous signal for f0(1710)K+Kf_0(1710) \to K^+K^- and a peak at higher mass which may be fitted with f2(2150)KKˉf_2(2150) \to K\bar K. From a combined analysis with ωπ+π\omega \pi ^+ \pi ^- data, the branching ratio BR(f0(1710)ππ)/BR(f0(1710)KKˉ)BR(f_0(1710)\to\pi\pi)/BR(f_0(1710) \to K\bar K) is <0.11< 0.11 at the 95% confidence level.Comment: 11 pages, 5 figures. Submitted to Phys. Lett.

    BESII Detector Simulation

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    A Monte Carlo program based on Geant3 has been developed for BESII detector simulation. The organization of the program is outlined, and the digitization procedure for simulating the response of various sub-detectors is described. Comparisons with data show that the performance of the program is generally satisfactory.Comment: 17 pages, 14 figures, uses elsart.cls, to be submitted to NIM

    Measurement of branching fractions for the inclusive Cabibbo-favored ~K*0(892) and Cabibbo-suppressed K*0(892) decays of neutral and charged D mesons

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    The branching fractions for the inclusive Cabibbo-favored ~K*0 and Cabibbo-suppressed K*0 decays of D mesons are measured based on a data sample of 33 pb-1 collected at and around the center-of-mass energy of 3.773 GeV with the BES-II detector at the BEPC collider. The branching fractions for the decays D+(0) -> ~K*0(892)X and D0 -> K*0(892)X are determined to be BF(D0 -> \~K*0X) = (8.7 +/- 4.0 +/- 1.2)%, BF(D+ -> ~K*0X) = (23.2 +/- 4.5 +/- 3.0)% and BF(D0 -> K*0X) = (2.8 +/- 1.2 +/- 0.4)%. An upper limit on the branching fraction at 90% C.L. for the decay D+ -> K*0(892)X is set to be BF(D+ -> K*0X) < 6.6%

    The σ\sigma pole in J/ψωπ+πJ/\psi \to \omega \pi^+ \pi^-

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    Using a sample of 58 million J/ψJ/\psi events recorded in the BESII detector, the decay J/ψωπ+πJ/\psi \to \omega \pi^+ \pi^- is studied. There are conspicuous ωf2(1270)\omega f_2(1270) and b1(1235)πb_1(1235)\pi signals. At low ππ\pi \pi mass, a large broad peak due to the σ\sigma is observed, and its pole position is determined to be (541±39)(541 \pm 39) - ii (252±42)(252 \pm 42) MeV from the mean of six analyses. The errors are dominated by the systematic errors.Comment: 15 pages, 6 figures, submitted to PL
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