15 research outputs found
Differences in the quality of interpersonal care in complementary and conventional medicine
<p>Abstract</p> <p>Background</p> <p>The study was part of a nationwide evaluation of complementary and alternative medicine (CAM) in Swiss primary care. The aim of the study was to compare patient-physician relationships and the respective patient-reported relief of symptoms between CAM and conventional primary care (COM).</p> <p>Methods</p> <p>A comparative observational study in Swiss primary care with written survey completed by patients who visited a GP one month earlier. 6133 patients older than 16 years of 170 certified CAM physicians, of 77 non-certified CAM physicians and of 71 conventional physicians were included. Patients completed a questionnaire aimed at symptom relief, patient satisfaction, fulfilment of expectations, and quality of patient-physician interaction (EUROPEP questionnaire).</p> <p>Results</p> <p>CAM physicians treated significantly more patients with chronic conditions than COM physicians. CAM Patients had significant higher healing expectations than COM patients. General patient satisfaction was significantly higher in CAM patients, although patient-reported symptom relief was significantly poorer. The quality of patient-physician communication was rated significantly better in CAM patients.</p> <p>Conclusions</p> <p>The study shows better patient-reported outcomes of CAM in comparison to COM in Swiss primary care, which is related to higher patient satisfaction due to better patient-physician communication of CAM physicians. More effective communication patterns of these physicians may play an important role in allowing patients to maintain more positive outcome expectations. The findings should promote formative efforts in conventional primary care to improve communication skills in order to reach the same levels of favourable patient outcomes.</p
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues
MicroRNAs (miRNAs) regulate target mRNAs through
a combination of translational repression and mRNA
destabilization, with mRNA destabilization dominating
at steady state in the few contexts examined
globally. Here, we extend the global steady-state
measurements to additional mammalian contexts
and find that regardless of the miRNA, cell type,
growth condition, or translational state, mRNA destabilization
explains most (66%.>90%) miRNAmediated
repression. We also determine the relative
dynamics of translational repression and mRNA
destabilization for endogenous mRNAs as a miRNA
is induced. Although translational repression occurs
rapidly, its effect is relatively weak, such that by the
time consequential repression ensues, the effect of
mRNA destabilization dominates. These results
imply that consequential miRNA-mediated repression
is largely irreversible and provide other insights
into the nature of miRNA-mediated regulation. They
also simplify future studies, dramatically extending
the known contexts and time points for which monitoring
mRNA changes captures most of the direct
miRNA effects.11461471sciescopu
OPRM1 and Diagnosis-Related Posttraumatic Stress Disorder in Binge-Drinking Patients Living with HIV
Micro-organic basis of functional gastrointestinal (GI) disorders: Role of microRNAs in GI pacemaking cells
Resilience Among Women with HIV: Impact of Silencing the Self and Socioeconomic Factors
In the U.S., women account for over a quarter of the approximately 50,000 annual new HIV diagnoses and face intersecting and ubiquitous adversities including gender inequities, sexism, poverty, violence, and limited access to quality education and employment. Women are also subjected to prescribed gender roles such as silencing their needs in interpersonal relationships, which may lessen their ability to be resilient and function adaptively following adversity. Previous studies have often highlighted the struggles encountered by women with HIV without focusing on their strengths. The present cross-sectional study investigated the relationships of silencing the self and socioeconomic factors (education, employment, and income) with resilience in a sample of women with HIV. The sample consisted of 85 women with HIV, diverse ethnic/racial groups, aged 24 – 65 enrolled at the Chicago site of the Women’s Interagency HIV Study in the midwestern region of the United States. Measures included the Connor-Davidson Resilience Scale -10 item and the Silencing the Self Scale (STSS). Participants showed high levels of resilience. Women with lower scores on the STSS (lower self-silencing) reported significantly higher resilience compared to women with higher STSS scores. Although employment significantly related to higher resilience, silencing the self tended to predict resilience over and above the contributions of employment, income, and education. Results suggest that intervention and prevention efforts aimed at decreasing silencing the self and increasing employment opportunities may improve resilience