Etiological factors in primary hepatic B-cell lymphoma

Sixty-four cases of malignant lymphoma involving the liver were examined. Of these, 20 cases were histologically confirmed to be primary hepatic B-cell lymphoma. Twelve of these 20 cases were diffuse large B-cell lymphoma (DLBCL) and eight cases were mucosa-associated lymphoid tissue (MALT) lymphoma. Of the 12 cases of DLBCL, six were immunohistologically positive for CD10 and/or Bcl6 (indicating a germinal center phenotype), six were positive for Bcl2, and five were positive for CD25. Eight of the 12 DLBCL cases (66.7%) and two of the eight MALT lymphoma cases (25%) had serum anti-hepatitis C virus (HCV) antibodies and HCV RNA. The incidence of HCV infection was significantly higher in the hepatic DLBCL cases than in systemic intravascular large B-cell cases with liver involvement (one of 11 cases, 9.1%) and T/NK-cell lymphoma cases (one of 19 cases, 5.3%) (p < 0.01 for both). Two hepatic DLBCL cases (16.7%) had rheumatoid arthritis treated with methotrexate, and four MALT lymphoma cases (50%) had Sjögren’s syndrome, primary biliary cirrhosis, or autoimmune hepatitis; one case in each of these two groups was complicated by chronic HCV-seropositive hepatitis. Although primary hepatic lymphoma is rare, persistent inflammatory processes associated with HCV infection or autoimmune disease may play independent roles in the lymphomagenesis of hepatic B cells

On the carlitz rank of permutation polynomials over finite fields:recent developments

The Carlitz rank of a permutation polynomial over a finite field Fq is a simple concept that was introduced in the last decade. In this survey article, we present various interesting results obtained by the use of this notion in the last few years. We emphasize the recent work of the authors on the permutation behavior of polynomials f + g, where f is a permutation over Fq of a given Carlitz rank, and g∈Fq[x] is of prescribed degree. The relation of this problem to the well-known Chowla–Zassenhaus conjecture is described. We also present some initial observations on the iterations of a permutation polynomial f∈Fq[x] and hence on the order of f as an element of the symmetric group S q

On the Scientific Work of Konstantin Ilyich Oskolkov

This chapter is a brief account of the life and the scientific work of K.I. Oskolkov