The Use of Ultrasonography to Study Teratogenicity in Ruminants: Evaluation of Ipomoea carnea in Goats

Background: Ipomoea carnea (I. carnea) is a poisonous plant found in Brazil and other tropical countries that often poison livestock. The plant contains the alkaloids calystegines and mainly swainsonine, which inhibit cellular enzymes and cause systematic cell death. The objective of this study was to evaluate the perinatal effects of I. carnea in goats. Methods: Forty-seven pregnant goats were randomly allocated into 5 treatment groups and given the following doses (g/kg BW) of I. carnea: 0 (IC0), 1.0 (IC1), 3.0 (IC3), 5.0 (IC5) and 7.5 (IC7). The treatment animals were given fresh I. carnea from day 27 of gestation to parturition. Weight gains and serum biochemistry were evaluated. Fetuses were evaluated using ultrasonographic measurements. Results: Goats from the IC7 group showed clinical signs of poisoning. Ultrasound examination revealed that I. carnea feeding in all treatment groups reduced fetal movement compared to the controls. There was an increase in the total number of birth defects (retrognathia and arthrogyposis) in the IC7 and IC5 groups compared to the controls. Conclusion: The results show that I. carnea has teratogenic potential in goats. In addition, ultrasounds were useful in evaluating fetotoxicity and teratogenicity. Birth Defects Res (Part B) 00:17, 2012. (c) 2012 Wiley Periodicals, Inc.Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo-FAPESP [2006/58729-2

Maternalismo, políticas públicas e benemerência no Brasil (1930-1945) Maternalism, state policy, and women's philanthropic activities in Brazil (1930-1945)

Este artigo tem por objetivos: 1. revisitar as propostas das entidades filantrópicas organizadas e administradas por mulheres na primeira metade do século XX; 2. repensar o papel que tiveram na elaboração de programas e no estabelecimento de políticas públicas; 3. chamar a atenção para a necessidade de uma releitura do movimento feminista brasileiro. O encaminhamento destes tópicos será feito a partir da análise do discurso maternalista. A pesquisa baseou-se principalmente na documentação levantada nos arquivos da Cruzada Pró Infância, entidade fundada em 1930, na cidade de São Paulo, e focalizará as propostas referentes à proteção da maternidade feitas pela sua diretora-presidente Pérola Byington, entre 1930-1945.<br>The objectives of this study are: 1. To review the proposals of philanthropic entities, organized and managed by women in the first half of the 20th century; 2. To rethink the role they played elaborating programs and establishing public policies; 3. To call attention to the need of reviewing the Brazilian feminist movement. The guide for these topics will be based on the analysis of the maternalist discourse. The research was based on documents from the archives of the Cruzada Pró Infância (Crusade Pro-Childhood) an entity founded in the city of Sao Paulo in 1930. It will focus on the proposals for maternity protection elaborated by Pérola Byington, its managing director between 1930-1945

O papel das ONGs na construção de políticas de saúde: a Aids, a saúde da mulher e a saúde mental The role of NGOs in designing public health policies: the Aids epidemic, women's health and mental health

Este artigo analisa iniciativas da sociedade civil na elaboração de políticas de saúde no Brasil a partir do exame de três casos em que a atuação de organizações não-governamentais teve papel relevante nas três últimas décadas: a epidemia de Aids, a saúde da mulher e a reforma psiquiátrica. Situa o surgimento das ONGs no contexto dos movimentos de participação civil no Brasil, identifica suas características distintivas em relação a outras formas de associação e compara as trajetórias específicas nos casos da Aids, da saúde da mulher e do movimento psiquiátrico. O texto indica dilemas comuns ao campo das organizações não-governamentais no final dos anos 90 e aponta a necessidade de estudos sobre a participação de organizações da sociedade civil no desenvolvimento de políticas sociais, em especial das políticas contra a violência.<br>This article evaluates a series of civil society initiatives concerning the design of Brazilian public health policies stemming from the analysis of three cases in which non-governmental organizations played a significant role in the three last decades: the Aids epidemic, women's health and the psychiatric reform. It studies the birth of NGOs in the context of civil society participation in the country, it identifies its distinctive characteristics in relation to other forms of association and it compares their specific paths in the case of Aids, women's health and the psychiatric movement. It points to common dilemmas in the field of NGOs at the end of the 1990's and the need for studies about the participation of civil society organizations in the development of social public policies, specially in the area of public policies concerning violence