Quark core impact on hybrid star cooling

In this paper we investigate the thermal evolution of hybrid stars, objects composed of a quark matter core, enveloped by ordinary hadronic matter. Our purpose is to investigate how important are the microscopic properties of the quark core to the thermal evolution of the star. In order to do that we use a simple MIT bag model for the quark core, and a relativistic mean field model for the hadronic envelope. By choosing different values for the microscopic parameters (bag constant, strange quark mass, strong coupling constant) we obtain hybrid stars with different quark core properties. We also consider the possibility of color superconductivity in the quark core. With this simple approach, we have found a set of microscopic parameters that lead to a good agreement with observed cooling neutron stars. Our results can be used to obtain clues regarding the properties of the quark core in hybrid stars, and can be used to refine more sophisticated models for the equation of state of quark matter.Comment: 8 pages, 10 figures. Accepted for publication in Physical Review

Rotating Neutron Stars in a Chiral SU(3) Model

We study the properties of rotating neutron stars within a generalized chiral SU(3)-flavor model. The influence of the rotation on the inner structure and the hyperon matter content of the star is discussed. We calculate the Kepler frequency and moments of inertia of the neutron star sequences. An estimate for the braking index of the associated pulsars is given.Comment: 14 pages, 9 figure

Fractal dimension of domain walls in the Edwards-Anderson spin glass model

We study directly the length of the domain walls (DW) obtained by comparing the ground states of the Edwards-Anderson spin glass model subject to periodic and antiperiodic boundary conditions. For the bimodal and Gaussian bond distributions, we have isolated the DW and have calculated directly its fractal dimension $d_f$. Our results show that, even though in three dimensions $d_f$ is the same for both distributions of bonds, this is clearly not the case for two-dimensional (2D) systems. In addition, contrary to what happens in the case of the 2D Edwards-Anderson spin glass with Gaussian distribution of bonds, we find no evidence that the DW for the bimodal distribution of bonds can be described as a Schramm-Loewner evolution processes.Comment: 6 pages, 5 figures. Accepted for publication in PR

Hybrid Stars in an SU(3) Parity Doublet Model

We apply an extended version of the SU(3) parity model, containing quark degrees of freedom, to study neutron stars. The model successfully reproduces the main thermodynamic features of QCD which allows us to describe the composition of dense matter. Chiral symmetry restoration is realized inside the star and the chiral partners of the baryons appear, their masses becoming degenerate. Furthermore, quark degrees of freedom appear in a transition to a deconfined state. Performing an investigation of the macroscopic properties of neutron stars, we show that observational constraints, like mass and thermal evolution, are satisfied and new predictions can be made

Estimating novel potential drug targets of Plasmodium falciparum by analysing the metabolic network of knock-out strains in silico

Malaria is one of the world’s most common and serious diseases causing death of about 3 million people each year. Its most severe occurrence is caused by the protozoan Plasmodium falciparum. Biomedical research could enable treating the disease by effectively and specifically targeting essential enzymes of this parasite. However, the parasite has developed resistance to existing drugsmaking it indispensable to discover new drugs. We have established a simple computational tool which analyses the topology of the metabolic network of P. falciparum to identify essential enzymes as possible drug targets.Weinvestigated the essentiality of a reaction in the metabolic network by deleting (knocking-out) such a reaction in silico. The algorithmselected neighbouring compounds of the investigated reaction that had to be produced by alternative biochemical pathways. Using breadth first searches, we tested qualitatively if these products could be generated by reactions that serve as potential deviations of the metabolic flux. With this we identified 70 essential reactions. Our results were compared with a comprehensive list of 38 targets of approved malaria drugs. When combining our approach with an in silico analysis performed recently [Yeh, I., Hanekamp, T., Tsoka, S., Karp, P.D., Altman, R.B., 2004. Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery. Genome Res. 14, 917–924] we could improve the precision of the prediction results. Finally we present a refined list of 22 new potential candidate targets for P. falciparum, half of which have reasonable evidence to be valid targets against micro-organisms and cancer

SLE local martingales in logarithmic representations

A space of local martingales of SLE type growth processes forms a representation of Virasoro algebra, but apart from a few simplest cases not much is known about this representation. The purpose of this article is to exhibit examples of representations where L_0 is not diagonalizable - a phenomenon characteristic of logarithmic conformal field theory. Furthermore, we observe that the local martingales bear a close relation with the fusion product of the boundary changing fields. Our examples reproduce first of all many familiar logarithmic representations at certain rational values of the central charge. In particular we discuss the case of SLE(kappa=6) describing the exploration path in critical percolation, and its relation with the question of operator content of the appropriate conformal field theory of zero central charge. In this case one encounters logarithms in a probabilistically transparent way, through conditioning on a crossing event. But we also observe that some quite natural SLE variants exhibit logarithmic behavior at all values of kappa, thus at all central charges and not only at specific rational values.Comment: 40 pages, 7 figures. v3: completely rewritten, new title, new result

Calogero-Sutherland eigenfunctions with mixed boundary conditions and conformal field theory correlators

We construct certain eigenfunctions of the Calogero-Sutherland hamiltonian for particles on a circle, with mixed boundary conditions. That is, the behavior of the eigenfunction, as neighbouring particles collide, depend on the pair of colliding particles. This behavior is generically a linear combination of two types of power laws, depending on the statistics of the particles involved. For fixed ratio of each type at each pair of neighboring particles, there is an eigenfunction, the ground state, with lowest energy, and there is a discrete set of eigenstates and eigenvalues, the excited states and the energies above this ground state. We find the ground state and special excited states along with their energies in a certain class of mixed boundary conditions, interpreted as having pairs of neighboring bosons and other particles being fermions. These particular eigenfunctions are characterised by the fact that they are in direct correspondence with correlation functions in boundary conformal field theory. We expect that they have applications to measures on certain configurations of curves in the statistical O(n) loop model. The derivation, although completely independent from results of conformal field theory, uses ideas from the "Coulomb gas" formulation.Comment: 35 pages, 9 figure

Ultra-Transparent Antarctic Ice as a Supernova Detector

We have simulated the response of a high energy neutrino telescope in deep Antarctic ice to the stream of low energy neutrinos produced by a supernova. The passage of a large flux of MeV-energy neutrinos during a period of seconds will be detected as an excess of single counting rates in all individual optical modules. We update here a previous estimate of the performance of such an instrument taking into account the recent discovery of absorption lengths of several hundred meters for near-UV photons in natural deep ice. The existing AMANDA detector can, even by the most conservative estimates, act as a galactic supernova watch.Comment: 9 pages, Revtex file, no figures. Postscript file also available from http://phenom.physics.wisc.edu/pub/preprints/1995/madph-95-888.ps.Z or from ftp://phenom.physics.wisc.edu/pub/preprints/1995/madph-95-888.ps.