6,845 research outputs found
Standing on Shaky Ground: Americans' Experiences With Economic Insecurity
Based on 2009 Surveys of Economic Risk Perceptions and Insecurity, examines Americans' experience of economic insecurity, such as frequency and duration, buffers against hardship, and concerns by income, family structure, race/ethnicity, and education
Regulation of Francisella Tularensis Virulence
Francisella tularensis is one of the most virulent bacteria known and a Centers for Disease Control and Prevention Category A select agent. It is able to infect a variety of animals and insects and can persist in the environment, thus Francisella spp. must be able to survive in diverse environmental niches. However, F. tularensis has a surprising dearth of sensory and regulatory factors. Recent advancements in the field have identified new functions of encoded transcription factors and greatly expanded our understanding of virulence gene regulation. Here we review the current knowledge of environmental adaptation by F. tularensis, its transcriptional regulators and their relationship to animal virulence
Soft Manifold Dynamics Behind Negative Thermal Expansion
Minimal models are developed to examine the origin of large negative thermal
expansion (NTE) in under-constrained systems. The dynamics of these models
reveals how underconstraint can organize a thermodynamically extensive manifold
of low-energy modes which not only drives NTE but extends across the Brillioun
zone. Mixing of twist and translation in the eigenvectors of these modes, for
which in ZrW2O8 there is evidence from infrared and neutron scattering
measurements, emerges naturally in our model as a signature of the dynamics of
underconstraint.Comment: 5 pages, 3 figure
RNAs from two independently isolated defective interfering particles of Sindbis virus contain a cellular tRNA sequence at their 5' ends.
Body mass index, abdominal fatness, fat mass and the risk of atrial fibrillation: a systematic review and dose–response meta-analysis of prospective studies
Different adiposity measures have been associ- ated with increased risk of atrial fibrillation, however, results have previously only been summarized for BMI. We therefore conducted a systematic review and meta- analysis of prospective studies to clarify the association between different adiposity measures and risk of atrial fibrillation. PubMed and Embase databases were searched up to October 24th 2016. Summary relative risks (RRs) were calculated using random effects models. Twenty-nine unique prospective studies (32 publications) were included. Twenty-five studies (83,006 cases, 2,405,381 participants) were included in the analysis of BMI and atrial fibrillation. The summary RR was 1.28 (95% confidence interval: 1.20–1.38, I 2 = 97%) per 5 unit increment in BMI, 1.18 (95% CI: 1.12–1.25, I 2 = 73%, n = 5) and 1.32 (95% CI: 1.16–1.51, I 2 = 91%, n = 3) per 10 cm increase in waist and hip circumference, respectively, 1.09 (95% CI: 1.02–1.16, I 2 = 44%, n = 4) per 0.1 unit increase in waist- to-hip ratio, 1.09 (95% CI: 1.02–1.16, I 2 = 94%, n = 4) per 5 kg increase in fat mass, 1.10 (95% CI: 0.92–1.33, I 2 = 90%, n = 3) per 10% increase in fat percentage, 1.10 (95% CI: 1.08–1.13, I 2 = 74%, n = 10) per 5 kg increase in weight, and 1.08 (95% CI: 0.97–1.19, I 2 = 86%, n = 2) per 5% increase in weight gain. The association between BMI and atrial fibrillation was non- linear, p nonlinearity \ 0.0001, with a stronger association at higher BMI levels, however, increased risk was observed even at a BMI of 22–24 compared to 20. In conclusion, general and abdominal adiposity and higher body fat mass increase the risk of atrial fibrillation
Professionalisation of sport federations - a multi-level framework for analysing forms, causes and consequences
Research question: International and national sport federations as well as their member organisations are key actors within the sport system and have a wide range of relationships outside the sport system (e.g. with the state, sponsors, and the media). They are currently facing major challenges such as growing competition in top-level sports, democratisation of sports with 'sports for all' and
sports as the answer to social problems. In this context, professionalising sport organisations seems to be an appropriate strategy to face these challenges and current problems. We define the professionalisation of sport organisations as an organisational process of transformation leading towards organisational rationalisation, efficiency and business-like management. This has led to a profound organisational change, particularly within sport federations, characterised by the strengthening of institutional management (managerialism) and the implementation of efficiency-based management instruments and paid staff. Research methods: The goal of this article is to review the current international literature and establish a global understanding of and theoretical framework for
analysing why and how sport organisations professionalise and what consequences this may have.
Results and findings: Our multi-level approach based on the social theory of action integrates the current concepts for analysing professionalisation in sport federations. We specify the framework for the following research perspectives: (1)
forms, (2) causes and (3) consequences, and discuss the reciprocal relations between sport federations and their member organisations in this context. Implications: Finally, we work out a research agenda and derive general methodological consequences for the investigation of professionalisation processes in sport organisations
Measuring the vertical age structure of the Galactic disc using asteroseismology and SAGA
The existence of a vertical age gradient in the Milky Way disc has been
indirectly known for long. Here, we measure it directly for the first time with
seismic ages, using red giants observed by Kepler. We use Stroemgren photometry
to gauge the selection function of asteroseismic targets, and derive colour and
magnitude limits where giants with measured oscillations are representative of
the underlying population in the field. Limits in the 2MASS system are also
derived. We lay out a method to assess and correct for target selection effects
independent of Galaxy models. We find that low mass, i.e. old red giants
dominate at increasing Galactic heights, whereas closer to the Galactic plane
they exhibit a wide range of ages and metallicities. Parametrizing this as a
vertical gradient returns approximately 4 Gyr/kpc for the disc we probe,
although with a large dispersion of ages at all heights. The ages of stars show
a smooth distribution over the last 10 Gyr, consistent with a mostly quiescent
evolution for the Milky Way disc since a redshift of about 2. We also find a
flat age-metallicity relation for disc stars. Finally, we show how to use
secondary clump stars to estimate the present-day intrinsic metallicity spread,
and suggest using their number count as a new proxy for tracing the ageing of
the disc. This work highlights the power of asteroseismology for Galactic
studies; however, we also emphasize the need for better constraints on stellar
mass-loss, which is a major source of systematic age uncertainties in red giant
stars.Comment: MNRAS, accepted. SAGA website and data at
http://www.mso.anu.edu.au/saga/data_access.htm
Long-term CO2 enrichment of a forest ecosystem : implications for forest regeneration and succession
Author Posting. © Ecological Society of America, 2007. This article is posted here by permission of Ecological Society of America for personal use, not for redistribution. The definitive version was published in Ecological Applications 17 (2007): 1198–1212, doi:10.1890/05-1690.The composition and successional status of a forest affect carbon storage and net ecosystem productivity, yet it remains unclear whether elevated atmospheric carbon dioxide (CO2) will impact rates and trajectories of forest succession. We examined how CO2 enrichment (+200 μL CO2/L air differential) affects forest succession through growth and survivorship of tree seedlings, as part of the Duke Forest free-air CO2 enrichment (FACE) experiment in North Carolina, USA. We planted 2352 seedlings of 14 species in the low light forest understory and determined effects of elevated CO2 on individual plant growth, survival, and total sample biomass accumulation, an integrator of plant growth and survivorship over time, for six years. We used a hierarchical Bayes framework to accommodate the uncertainty associated with the availability of light and the variability in growth among individual plants.
We found that most species did not exhibit strong responses to CO2. Ulmus alata (+21%), Quercus alba (+9.5%), and nitrogen-fixing Robinia pseudoacacia (+230%) exhibited greater mean annual relative growth rates under elevated CO2 than under ambient conditions. The effects of CO2 were small relative to variability within populations; however, some species grew better under low light conditions when exposed to elevated CO2 than they did under ambient conditions. These species include shade-intolerant Liriodendron tulipifera and Liquidambar styraciflua, intermediate-tolerant Quercus velutina, and shade-tolerant Acer barbatum, A. rubrum, Prunus serotina,Ulmus alata, and Cercis canadensis. Contrary to our expectation, shade-intolerant trees did not survive better with CO2 enrichment, and population-scale responses to CO2 were influenced by survival probabilities in low light. CO2 enrichment did not increase rates of sample biomass accumulation for most species, but it did stimulate biomass growth of shade-tolerant taxa, particularly Acer barbatum and Ulmus alata. Our data suggest a small CO2 fertilization effect on tree productivity, and the possibility of reduced carbon accumulation rates relative to today's forests due to changes in species composition.This research was supported by the
Office of Science (BER), U.S. Department of Energy, Grant
No. DE-FG02-95ER62083, and by Terrestrial Ecosystems and
Global Change (TECO) Grant No. DE-F602-97ER62463
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