Complexity Theory for a New Managerial Paradigm: A Research Framework

In this work, we supply a theoretical framework of how organizations can embed complexity management and sustainable development into their policies and actions. The proposed framework may lead to a new management paradigm, attempting to link the main concepts of complexity theory, change management, knowledge management, sustainable development, and cybernetics. We highlight how the processes of organizational change have occurred as a result of the move to adapt to the changes in the various global and international business environments and how this transformation has led to the shift toward the present innovation economy. We also point how organizational change needs to deal with sustainability, so that the change may be consistent with present needs, without compromising the future

A apropriação e uso de conhecimentos de gestão para a mudança de cultura na enfermagem como disciplina

Reflexão acerca da possibilidade do uso de conhecimentos de gestão no processo do trabalho em saúde, apresentando aspectos gerais do processo gerencial e considerações sobre o trabalho da enfermagem no contexto geral do trabalho em saúde e elementos da cultura organizacional e suas implicações no contexto do trabalho da Enfermagem. A manutenção do modelo de gerência tradicional como o principal norteador da organização do trabalho na área da saúde vem inibindo a produção da Disciplina Enfermagem. Urge, na Enfermagem, que se propiciem aos trabalhadores possibilidades para criar, desenvolver, usar novas ferramentas e tecnologias para gerenciar o processo de trabalho, encontrar formas criativas e inovadoras de produzir e viver, ter qualidade de vida pessoal e profissional, ser ético/estético, dentre outros. Apropriar–se e utilizar conhecimentos acerca das diferentes formas de gerenciar o processo de produção no trabalho apresenta–se como uma importante estratégia capaz de propiciar o desenvolvimento da Enfermagem como disciplina.This project is a reflection concerning the possibility of using management knowledge in the process of health care work, presenting general aspects of the management process and considerations about nursing work in the general context of health care work, and elements of the organizational culture and their implications in the context of Nursing work. The maintenance of the traditional management model as the main orientation of work organization in health care has been inhibiting production within the academic area of Nursing. It urges, in Nursing, that workers are given possibilities to create, develop, and use new tools and technologies to manage the work process; to find creative and innovative forms to produce and to live, attaining satisfactory quality of life in personal and professional ways, and being ethical/aesthetic, amongst others. Taking possession and using knowledge concerning the different forms of managing the productive process in work is presented as an important strategy capable of making possible the development of Nursing as a subject.Este trabajo es una reflexión acerca de la posibilidad del uso de conocimientos de gestión en el proceso del trabajo en el área de la salud, presentando aspectos generales del proceso administrativo y las consideraciones sobre el trabajo de la enfermería en el contexto general del trabajo en la salud y los elementos de la cultura organizativa y sus implicaciones en el contexto del trabajo de la Enfermería. El mantenimiento del modelo de la gerencia tradicional como el principal orientador de la organización del trabajo en el área de la salud viene cohibiendo la producción de la Asignatura de Enfermería. Es urgente, en la Enfermería, que se propicien en los trabajadores las debidas posibilidades para crear, desarrollar, usar nuevas herramientas y tecnologías para administrar el proceso de trabajo, encontrar formas creativas e innovadoras de producir y vivir, tener calidad de vida personal y profesional, ser ético/estético, entre otros. Apropiarse y utilizar conocimientos acerca de las diferentes formas de administrar el proceso de producción en el trabajo se presenta como una importante estrategia capaz de deparar y proporcionar el desarrollo de la Enfermería como una asignatura

Modelagem e análise de serviços de saúde baseados em Redes de Petri interpretadas

Este trabalho introduz as Redes de Petri para modelagem e análise de sistemas de saúde que além da complexidade de suas atividades, envolve na sua concepção, implementação, operação e tomada de decisões, vários e diferentes profissionais. Os modelos são desenvolvidos em PFS (Production Flow Schema) e MFG (Mark Flow Graph) que são interpretações de redes de Petri, explicitando os recursos envolvidos e o fluxo de itens (pessoas, equipamentos, informações). Os serviços do Ambulatório do Hospital das Clínicas da Universidade de São Paulo são utilizados como estudo de caso para comprovar as vantagens da presente proposta.<br>This paper introduces the Petri net for modelling and analysis of health systems where beyond the complexity of they activities, involves in its conception, implementation, operation and decision making several and differents professionals. The models are developed in PFS (Production Flow Schema) and MFC (Mark Flow Graph) that are interpretations of Peri nets aiming the explicit identification of resources and flow of itens (material and information). The services of the ambulatory of Clinic Hospital of University of São Paulo is considered in a case study to confirm the advantages of the proposal

Can Current Conceptions of Strategy Support the Formulation, Analysis and Execution of Service Strategies?

2019, Springer Nature Switzerland AG. A vast literature dating back many decades addresses the question of business strategies and their definition, formulation and execution. Relatively little has been done on the question of service strategies. Service strategies represent a sub-class of the general class of business strategies which require special attention for any organization engaged in the provision of services. This paper explores the extent to which current conceptions of strategy support the definition of service strategies

c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis

Oncogenic c-Myc renders cells sensitive to TRAIL-induced apoptosis, and existing data suggest that c-Myc sensitizes cells to apoptosis by promoting activation of the mitochondrial apoptosis pathway. However, the molecular mechanisms linking the mitochondrial effects of c-Myc to the c-Myc-dependent sensitization to TRAIL have remained unresolved. Here, we show that TRAIL induces a weak activation of procaspase-8 but fails to activate mitochondrial proapoptotic effectors Bax and Bak, cytochrome c release or downstream effector caspase-3 in non-transformed human fibroblasts or mammary epithelial cells. Our data is consistent with the model that activation of oncogenic c-Myc primes mitochondria through a mechanism involving activation of Bak and this priming enables weak TRAIL-induced caspase-8 signals to activate Bax. This results in cytochrome c release, activation of downstream caspases and postmitochondrial death-inducing signaling complex -independent augmentation of caspase-8-Bid activity. In conclusion, c-Myc-dependent priming of the mitochondrial pathway is critical for the capacity of TRAIL-induced caspase-8 signals to activate effector caspases and for the establishment of lethal caspase feedback amplification loop in human cells