13 research outputs found
The safety and efficacy of AphtoFix® mouth ulcer cream in the management of recurrent aphthous stomatitis
Full text linkCloud Resource Demand Prediction using Machine Learning in the Context of QoS Parameters
No full textRural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample
No full textIdentification of Risks Related to Integrated Product Service Offerings of Rail Infrastructure: A Swedish Case
No full textOsteonecrosis of the Jaw—a Bone Site-Specific Effect of Bisphosphonates
No full textA known complication that can occur in patients using bisphosphonates (BPs) is osteonecrosis of the jaw (ONJ). ONJ features bone exposure that may be associated with severe pain, swelling, local infection, and pathological fracture of the jaw. Current literature indicates that a complex combination of factors is necessary to induce ONJ. Several hypotheses about the pathophysiology of ONJ were previously reported. Here, we review these hypotheses and introduce new ideas and suggestions on this topic, focusing on bone site-specific cells, and the effect that BPs and other anti-resorptive drugs have on those cells. Gaining more insight into bone site-specific effects may help to better understand the pathogenesis ONJ, and contribute to the development of new bone site-specific anti-resorptive drugs
Differential diagnosis and clinical management of periapical radiopaque/hyperdense jaw lesions
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Esophageal motility disorders: new perspectives from high-resolution manometry and histopathology
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