Strategic entrepreneurship in the future: Theoretical views

The paper describes the role and importance of strategy in contemporary entrepreneurship, which operates under conditions of rapid change. Strategic Enterprise includes a set of entrepreneurial actions undertaken for the purpose of strategic perspective. It describes the key characteristics of modern entrepreneurs with strategic emphasis on the needs of the strategic analysis of business opportunities and possibilities of business enterprises in the specific conditions, at the beginning of the third millennium

THE ANALYSIS FOR POSSIBILITIES OF COMMODITY FUTURES INTRODUCTION IN NATIONAL FINANCIAL SYSTEM

The main goal of this Article is to, based on short analysis of basic futures characteristics as commodity and financial instruments, as well as contemporary situation of national commodity and financial market development, study the possibilities for commodity futures introduction in national financial system. The current year proved that unexpected natural circumstances, such as draught, could provoke the weaker harvest in agricultural production, having, on the other hand, many negative consequences, from poor market supply, through higher prices and potential inflation impact, to other market disturbances with many negative effects on general economic stability. The final part of the paper indicates the real possibilities for commodity futures introduction in Serbia, particularly in domain of their application in agribusiness and necessary steps which should be taken in order to realize its development and application

Synthesis of 5-azaandrostane-3b,17b-diol protected at the 17b-hydroxyl group

In the present paper, the preparation of 3b-hydroxy-17b-dimethyl-tert-butylsilyloxy-5-azaandrostane (15) in fourteen steps is described. B-nor-17-oxoandrost-5-en-3b-yl acetate (1) was used as the starting material, which was transformed to the key intermediate of the synthesis, B-nor-17b-dimethyl-tert-butylsilyloxyandrost-4-en-3b-yl acetate (7)

Efficiency of chewable toothbrush in reduction of dental plaque in students

Abstract Background Besides classical and electrical toothbrushes market offers tooth brushes that can be chewed, like chewing gums. The aim of this study was to show the effectiveness of chewable toothbrush versus a conventional brush in the students’ population. Methods The prospective study included 346 students. For this research, we used a e-questionnaire for “smart” phones, that students completed outside the dental office. Respondents are divided into two groups: control group used conventional toothbrushes, respondents from the tested group used chewable toothbrush. For assessment of accumulation of the plaque we used TQHI index. For testing statistical hypotheses, the following were used: t-test for two independent samples and analysis of the variance of repeated measurements. Results Before brushing teeth, the average TQHI value for chewable brushes is 2.8 ± 0.3, while conventional is 2.7 ± 0.3, which is not a statistically significant difference (p = 0.448). After brushing teeth, the average TQHI value for chewable brushes is 2.0 ± 0.1, while conventional 2.0 ± 0.3, which is also not statistically significant (p = 0.729). Observing the index of the plaque values on the tooth surfaces in the upper jaw, in both groups, there was a statistically significant change in the amount of plaque in time (p < 0.001). There is a statistically significant interaction between groups and changes in the amount of plaque in the observed period (p = 0.013). Conclusions The fact that there is no significant difference in the effectiveness of the tested brushes indicates the benefits of using chewable toothbrushes in order to reduce plaque, primarily in the inability to use conventional brushes

Pedicled Radial Forearm &ldquo;Free&rdquo; Flap for Intraoral Reconstruction Based on an Unexpectedly High Origin of the Radial Artery&mdash;Case Report

Background: Radial forearm free flap (RFFF) is considered one of the workhorses in modern head and neck reconstruction surgery due to its technical simplicity, versatility and less time-consuming harvest. Methods: In this report, we present the case of a 56-year-old woman with sublingual squamous cell carcinoma (SCC) who underwent surgical resection and reconstruction of the defect with a RFFF. Results: The preoperative Allen test showed normal blood flow, and the ultrasound did not recognize any blood vessel abnormalities in the left arm. However, during the RFFF harvest, when the dissection of the pedicle came to the cubital fossa, there was no brachial artery bifurcation. While trying to find the bifurcation, the dissection almost came to the axillary region. Hence, the RFFF was converted to a pedicle flap and was pulled through to the intraoral defect where it was used for reconstruction. Conclusions: Hence, during the preoperative radiological ultrasound, besides the usual characteristics such as the radial artery diameter, flow and possible obstructions, it is also important to explore if there are any other anatomical abnormalities that could influence the operation

The Association between the Level of Advanced Glycation End Products and Objective Skin Quality Parameters

Advanced glycation end products (AGEs) represent an endogenously produced or exogenously derived group of compounds derived from nonenzymatic glycation. Recent experimental studies are suggesting that AGEs could play an important role in the skin’s quality and its aging process. Hence, the aim of this study was to clinically evaluate the AGEs and skin quality parameters across different age groups in the general population. The study included 237 participants. Melanin, erythema, hydration, friction and transepidermal water loss (TEWL) were evaluated using noninvasive probes, while AGEs were evaluated using a skin autofluorescence reader. There was a significant positive correlation between AGEs and the amount of melanin (p &lt; 0.001), erythema (p &lt; 0.001) and TEWL (p &lt; 0.001), while there was a significant negative correlation between AGEs and hydration (p &lt; 0.001) and friction (p &lt; 0.001). After dividing the sample into three groups depending on their age, in all three groups, there was a significant positive correlation between AGEs and the melanin count (p &lt; 0.001) and TEWL (p &lt; 0.001), while there was a significant negative correlation between AGEs and skin hydration (p &lt; 0.001). Multiple linear regression analysis showed that the level of AGEs as a dependent variable retained a significant association with age (p &lt; 0.001), melanin (p &lt; 0.001), erythema (p = 0.005) and TEWL (p &lt; 0.001) as positive predictors. Moreover, AGEs retained a significant association with skin hydration (p &lt; 0.001) and friction (p = 0.017) as negative predictors. These outcomes imply that AGEs could be linked with the complex physiology of the skin and its aging process.</jats:p