Assessing chronic disease management in European health systems. Concepts and approaches

This book comprises two volumes and builds on the findings of the DISMEVAL project (Developing and validating DISease Management EVALuation methods for European health care systems), funded under the European Union’s (EU) Seventh Framework Programme (FP7) (Agreement no. 223277). DISMEVAL was a three-year European collaborative project conducted between 2009 and 2011. It contributed to developing new research methods and generating the evidence base to inform decision-making in the field of chronic disease management evaluation (www.dismeval.eu). In this book, we report on the findings of the project’s first phase, capturing the diverse range of contexts in which new approaches to chronic care are being implemented and evaluating the outcomes of these initiatives using an explicit comparative approach and a unified assessment framework. In this first volume, we describe the range of approaches to chronic care adopted in 12 European countries. By reflecting on the facilitators and barriers to implementation, we aim to provide policy-makers and practitioners with a portfolio of options to advance chronic care approaches in a given policy context. In volume II (available online at http://www.euro.who.int/en/about-us/ partners/observatory/studies), we present detailed overviews of each of the 12 countries reviewed for this work and which informed the overview presented in the first volume of the book

Volume Stabilization via α′\alpha^\prime Corrections in Type IIB Theory with Fluxes

We consider the Type IIB string theory in the presence of various extra $7/\bar 7$-brane pairs compactified on a warped Calabi-Yau threefold that admits a conifold singularity. We demonstrate that the volume modulus can be stabilized perturbatively at a non-supersymmetric $AdS_4/dS_4$ vacuum by the effective potential that includes the stringy $(\alpha^\prime)^3$ correction obtained by Becker {\it et al.} together with a combination of positive tension and anomalous negative tension terms generated by the additional 7-brane-antibrane pairs.Comment: 20 pages, 4 figures, parts of introduction and conclusions are modifie

Open Problems on Central Simple Algebras

We provide a survey of past research and a list of open problems regarding central simple algebras and the Brauer group over a field, intended both for experts and for beginners.Comment: v2 has some small revisions to the text. Some items are re-numbered, compared to v

Tachyon Condensation and Black Strings

We show that under certain conditions, closed string tachyon condensation produces a topology changing transition from black strings to Kaluza-Klein "bubbles of nothing." This can occur when the curvature at the horizon is much smaller than the string scale, so the black string is far from the correspondence point when it would make a transition to an excited fundamental string. This provides a dramatic new endpoint to Hawking evaporation. A similar transition occurs for black p-branes, and can be viewed as a nonextremal version of a geometric transition. Applications to AdS black holes and the AdS soliton are also discussed.Comment: 23 pages, 1 figure, v2: references adde

Stable de Sitter vacua in N=2, D=5 supergravity

We find 5D gauged supergravity theories exhibiting stable de Sitter vacua. These are the first examples of stable de Sitter vacua in higher-dimensional (D>4) supergravity. Non-compact gaugings with tensor multiplets and R-symmetry gauging seem to be the essential ingredients in these models. They are however not sufficient to guarantee stable de Sitter vacua, as we show by investigating several other models. The qualitative behaviour of the potential also seems to depend crucially on the geometry of the scalar manifold.Comment: 26 pages, v2:typos corrected, published versio

A New Handle on de Sitter Compactifications

We construct a large new class of de Sitter (and anti de Sitter) vacua of critical string theory from flux compactifications on products of Riemann surfaces. In the construction, the leading effects stabilizing the moduli are perturbative. We show that these effects self-consistently dominate over standard estimates for further $\alpha^\prime$ and quantum corrections, via tuning available from large flux and brane quantum numbers.Comment: 26 pages, harvmac big. v2: Correction generalizing specific ingredients required for tunable negative term; conclusions and structure of potential unchange

The Scaling of the No Scale Potential and de Sitter Model Building

We propose a variant of the KKLT (A)dS flux vacuum construction which does not require an antibrane to source the volume modulus. The strategy is to find nonzero local minima of the no-scale potential in the complex structure and dilaton directions in moduli space. The corresponding no-scale potential expanded about this point sources the volume modulus in the same way as does the antibrane of the KKLT construction. We exhibit explicit examples of such nonzero local minima of the no-scale potential in a simple toroidal orientifold model.Comment: 11 pages, harvmac big. v2: trivial typos fixe

Symmetric Points in the Landscape as Cosmological Attractors

In the landscape, if there is to be any prospect of scientific prediction, it is crucial that there be states which are distinguished in some way. The obvious candidates are states which exhibit symmetries. Here we focus on states which exhibit discrete symmetries. Such states are rare, but one can speculate that they are cosmological attractors. We investigate the problem in model landscapes and cosmologies which capture some of the features of candidate flux landscapes. In non-supersymmetric theories we find no evidence that such states might be cosmologically favored. In supersymmetric theories, simple arguments suggest that states which exhibit $R$ symmetries might be. Our considerations lead us to raise questions about some popular models of eternal inflation.Comment: 27 pages, latex, minor typo correcte